1. Life Sciences
Bioluminescence is the natural chemical process of light creation in some living creatures that makes fireflies flicker and some jellyfish glow. Scientists have long been interested in borrowing the secrets of these animals’ light-producing genes to create similar effects in vertebrates, for a variety of biomedical applications. UC Santa Cruz Assistant Professor of Biomolecular Engineering […]
  1. Biology
VPS13 proteins mediate lipid transfer across membranes. Among them, VPS13B is associated with Golgi membranes, and VPS13B mutations cause Cohen syndrome. In this issue, Ugur et al. (https://doi.org/10.1083/jcb.202311189) and Du et al. (https://doi.org/10.1083/jcb.202402083) reveal new VPS13B interactors and their functions in Golgi organization and trafficking.
  1. Environmental Science
In the face of the climate crisis, we often overlook one of its critical consequences: malnutrition. The connection between climate change and nutrition extends beyond health and food concerns; it is integral to overall sustainable development, and these connections must be more effectively integrated. A place to start that integration is the Conference of Parties […]
  1. Life Sciences
A recent study highlights that over one-third of Vietnam’s 329 mammal species are threatened with extinction. Conducted by German scientist Hanna Höffner of the University of Cologne and Cologne Zoo, alongside an international team, the research underscores Vietnam’s vital but fragile position as a biodiversity hub within the Indo-Burma Biodiversity Hotspot. Published in the open-access […]
  1. Life Sciences
Researchers have named two newly discovered freshwater snail species from Brazil after characters from The Lord of the Rings. Described in the open-access journal Zoosystematics and Evolution, Idiopyrgus eowynae and Idiopyrgus meriadoci were named in honour of Éowyn and Meriadoc Brandybuck from J.R.R. Tolkien’s iconic series. In their research paper, the authors explain the name […]
  1. Biology
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is a low-abundance signaling lipid that plays crucial roles in various cellular processes, including endolysosomal system structure/function, stress response, and cell cycle regulation. PI(3,5)P2 synthesis increases in response to environmental stimuli, yet its behavior in cycling cells under basal conditions remains elusive. Here, we analyzed spatiotemporal changes in PI(3,5)P2 levels during the […]
  1. Life Sciences
University of Maryland entomologists uncovered a unique relationship between two species of fungi known for their ability to invade, parasitize and kill insects efficiently. Instead of violently competing for the spoils of war, the two fungi peacefully cooperate and share their victims. The findings, published in the journal Public Library of Science (PLOS) Pathogens on […]
  1. Life Sciences
Tool use isn’t unique to humans. Chimpanzees use sticks as tools. Dolphins, crows, and elephants are known for their tool-use abilities, too. Now a report in the Cell Press journal Current Biology on November 8, 2024, highlights elephants’ remarkable skill in using a hose as a flexible shower head. As an unexpected bonus, researchers say […]
  1. Biology
We identify BEACH domain–containing proteins (BDCPs) as novel membrane coat proteins involved in the sorting of transmembrane proteins (TMPs) on the trans-Golgi network and tubular sorting endosomes. The seven typical mammalian BDCPs share a predicted alpha-solenoid-beta propeller structure, suggesting they have a protocoatomer origin and function. We map the subcellular localization of seven BDCPs based […]

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