Life Sciences Bioluminescent proteins made from scratch enable non-invasive, multi-functional biological imaging Bioluminescence is the natural chemical process of light creation in some living creatures that makes fireflies flicker and some jellyfish glow. Scientists have long been interested in borrowing the secrets of these animals’ light-producing genes to create similar effects in vertebrates, for a variety of biomedical applications. UC Santa Cruz Assistant Professor of Biomolecular Engineering […] Written by Admin November 14, 2024November 14, 2024 Saving Bookmark this article Bookmarked
Biology Stairway to the Golgi: Two paths VPS13B can go by VPS13 proteins mediate lipid transfer across membranes. Among them, VPS13B is associated with Golgi membranes, and VPS13B mutations cause Cohen syndrome. In this issue, Ugur et al. (https://doi.org/10.1083/jcb.202311189) and Du et al. (https://doi.org/10.1083/jcb.202402083) reveal new VPS13B interactors and their functions in Golgi organization and trafficking. Written by Admin November 13, 2024November 13, 2024 Saving Bookmark this article Bookmarked
Environmental Science The Critical Need to Align Climate and Nutrition Global Agendas at COP29 – State of the Planet In the face of the climate crisis, we often overlook one of its critical consequences: malnutrition. The connection between climate change and nutrition extends beyond health and food concerns; it is integral to overall sustainable development, and these connections must be more effectively integrated. A place to start that integration is the Conference of Parties […] Written by Guest November 13, 2024November 13, 2024 Saving Bookmark this article Bookmarked
Life Sciences More than one third of Vietnam’s mammal species are at risk of extinction, study finds A recent study highlights that over one-third of Vietnam’s 329 mammal species are threatened with extinction. Conducted by German scientist Hanna Höffner of the University of Cologne and Cologne Zoo, alongside an international team, the research underscores Vietnam’s vital but fragile position as a biodiversity hub within the Indo-Burma Biodiversity Hotspot. Published in the open-access […] Written by Admin November 13, 2024November 13, 2024 Saving Bookmark this article Bookmarked
Biotechnology GSK partners with Flagship startup to hunt for Parkinson’s drugs Under deal terms, GSK will give Vesalius Therapeutics $80 million in upfront and equity payments to identify treatments for Parkinson’s and another neurodegenerative condition. Written by Gwendolyn Wu November 13, 2024November 13, 2024 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1731483667.14a5860 Written by Admin November 13, 2024November 13, 2024 Saving Bookmark this article Bookmarked
Life Sciences The Shellowship of the Ring: Two new snail species named after Tolkien characters Researchers have named two newly discovered freshwater snail species from Brazil after characters from The Lord of the Rings. Described in the open-access journal Zoosystematics and Evolution, Idiopyrgus eowynae and Idiopyrgus meriadoci were named in honour of Éowyn and Meriadoc Brandybuck from J.R.R. Tolkien’s iconic series. In their research paper, the authors explain the name […] Written by Admin November 12, 2024November 12, 2024 Saving Bookmark this article Bookmarked
Biology PI(3,5)P 2 asymmetry during mitosis is essential for asymmetric vacuolar inheritance Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is a low-abundance signaling lipid that plays crucial roles in various cellular processes, including endolysosomal system structure/function, stress response, and cell cycle regulation. PI(3,5)P2 synthesis increases in response to environmental stimuli, yet its behavior in cycling cells under basal conditions remains elusive. Here, we analyzed spatiotemporal changes in PI(3,5)P2 levels during the […] Written by Admin November 12, 2024November 12, 2024 Saving Bookmark this article Bookmarked
Environmental Science Not much COP Not much COP Channel News brendan 11th November 2024 Teaser Media Written by brendan November 12, 2024November 12, 2024 Saving Bookmark this article Bookmarked
Life Sciences Insect-killing fungi find unexpected harmony in war University of Maryland entomologists uncovered a unique relationship between two species of fungi known for their ability to invade, parasitize and kill insects efficiently. Instead of violently competing for the spoils of war, the two fungi peacefully cooperate and share their victims. The findings, published in the journal Public Library of Science (PLOS) Pathogens on […] Written by Admin November 11, 2024November 11, 2024 Saving Bookmark this article Bookmarked
Life Sciences Elephant turns a hose into a sophisticated showering tool Tool use isn’t unique to humans. Chimpanzees use sticks as tools. Dolphins, crows, and elephants are known for their tool-use abilities, too. Now a report in the Cell Press journal Current Biology on November 8, 2024, highlights elephants’ remarkable skill in using a hose as a flexible shower head. As an unexpected bonus, researchers say […] Written by Admin November 10, 2024November 10, 2024 Saving Bookmark this article Bookmarked
Biology BEACH domain proteins function as cargo-sorting adaptors in secretory and endocytic pathways We identify BEACH domain–containing proteins (BDCPs) as novel membrane coat proteins involved in the sorting of transmembrane proteins (TMPs) on the trans-Golgi network and tubular sorting endosomes. The seven typical mammalian BDCPs share a predicted alpha-solenoid-beta propeller structure, suggesting they have a protocoatomer origin and function. We map the subcellular localization of seven BDCPs based […] Written by Admin November 10, 2024November 10, 2024 Saving Bookmark this article Bookmarked