ADC

Cystein as specific target for payloads in Tubulis ADC plattform
  1. Biotechnology

Tubulis secures €308m in record-breaking Series C financing  

Munich-based biotech Tubulis has closed a €308m (US$361m) Series C financing round – the largest of its kind for a European biotechnology company at the Series C stage and also the world’s largest financing for a private ADC (antibody–drug conjugate) developer. The round was led by Venrock Healthcare Capital Partners, joined by new investors Wellington […]
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Elevation Oncology Inc licences Synaffix BV's ADC platform
  1. Biotechnology

Elevation Oncology Inc licences Synaffix BV’s ADC platform

With the US$368m licence deal, Elevation Oncology, Inc is recognising Synaffix’s expertise in ADC development for the development of EO-1022. In contrast to Synaffix’s November deal with the Chinese BigHat Bioscience Co. Ltd, the US company does not book Lonza’s ADC manufacturing services that offers the same quality assurance process for all (clinicla) development phases, […]
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Anti-payload Antibodies: Facilitating ADC PK studies
  1. Biotechnology

Anti-payload Antibodies: Facilitating ADC PK studies

Sino Biological has successfully developed anti-payload antibodies which are used for analyzing the plasma/serum PK profiles, DAR values, and drug load distribution of ADC drugs. Anti-payload antibodies are used to evaluate the safety and efficacy of ADC drugs in the preclinical and clinical stages, empowering the ADC drug development process. As a great partner for […]
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Decoding the perfect steak: The hidden DNA behind Wagyu’s legendary marbling

Decoding the perfect steak: The hidden DNA behind Wagyu’s legendary marbling

Scientists at the University of Adelaide’s Davies Livestock Research Centre (DLRC) have unveiled the most comprehensive cattle genome ever assembled, a breakthrough expected to improve Wagyu breeding and enhance beef marbling. The research delivers a clearer picture of cattle genetics than any previous reference. “We have presented a near complete cattle genome that is 16 […]
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Worlwide

Decoding the perfect steak: The hidden DNA behind Wagyu’s legendary marbling

Decoding the perfect steak: The hidden DNA behind Wagyu’s legendary marbling

Scientists at the University of Adelaide’s Davies Livestock Research Centre (DLRC) have unveiled the most comprehensive cattle genome ever assembled, a breakthrough expected to improve Wagyu breeding and enhance beef marbling. The research delivers a clearer picture of cattle genetics than any previous reference. “We have presented a near complete cattle genome that is 16 […]
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Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

Despite the well-established role of condensin II in mitotic chromosome assembly, its function in interphase chromosome organization remains poorly understood. Here, we applied multiscale FISH techniques to human cell lines engineered for single or double depletion of condensin II and cohesin and examined their functional collaboration at two distinct stages of the cell cycle. Our […]
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