Biotechnology

Six bispecific antibody companies you should know about
  1. Biotechnology

Six bispecific antibody companies you should know about

Bispecific antibodies seem to be all the rage at the minute. Their ability to deliver targeted therapeutics to patients with a two-in-one approach by simultaneously binding to two different antigens or epitopes makes them an extremely attractive proposition to drug developers. This can be seen in the fact that there have been multiple big buyouts […]
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Tetraspecific B/NK cell better than T cell engagers
  1. Biotechnology

Tetraspecific B/NK cell better than T cell engagers

The therapeutic landscape for relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) is evolving toward targeted T-cell based immunotherapies, including CD19-targeted CAR-T and CD3xCD20 T-cell engaging (TCE) bispecificantibodies. Yet, there remains an unmet medical need for patients who are refractory to, or ineligible for these treatments. Leveraging natural killer NK cells emerges as a promising […]
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New tentative approval for Alembic drug dabigatran etexilate mesylate
  1. Biotechnology

New tentative approval for Alembic drug dabigatran etexilate mesylate

Copyright © DrugPatentWatch. Originally published at https://www.drugpatentwatch.com/blog/ Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs. There are three patents protecting this compound. Drug patent litigation for DABIGATRAN ETEXILATE MESYLATE. Nine suppliers are […]
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Tuberculosis research in 2024: the latest advancements
  1. Biotechnology

Tuberculosis research in 2024: the latest advancements

According to a new World Health Organization (WHO) report released on October 29, 2024, tuberculosis (TB) replaced COVID-19 to become the top cause of infectious disease-related deaths in 2023, as a total of 1.25 million people died from it last year. Additionally, 8.2 million people were newly diagnosed, up from 7.5 million in 2022. TB […]
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CEO and Chairman of the Executive Board
  1. Biotechnology

CEO and Chairman of the Executive Board

Jonathan Dickinson brings extensive biotech and pharma experience to Marseille-based Innate Pharma. He comes from Incyte, where he served as Executive Vice President and General Manager Europe since 2016. Prior to that, he gained significant leadership experience through several senior positions at oncology focused ARIAD Pharmaceuticals and Bristol-Myers Squibb. This followed a distinguished 13-year tenure […]
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New tentative approval for Alembic drug dabigatran etexilate mesylate
  1. Biotechnology

Which pharmaceutical companies have the most SPCs in Ireland?

Copyright © DrugPatentWatch. Originally published at https://www.drugpatentwatch.com/blog/ This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Ireland. SPCs are used in European Union and select others to encourage pharmaceutical innovation bycompensating for the long time needed to obtain regulatory approval for drugs. SPCscome into force only after the corresponding general […]
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SciVario® twin Bioprocess Controller: Addressing Current and Future Needs
  1. Biotechnology

SciVario® twin Bioprocess Controller: Addressing Current and Future Needs

Regardless of your research area, the SciVario twin was designed as a flexible and future proof system able to control one or two of the same or different bioreactors individually or in parallel. The innovative bay-drawer concept enables modular adaption of the system, eliminating the need to purchase a whole new system in case of […]
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Good Reads

VU Researchers Publish Study on the Mechanism of CRISPR-Cas “Protein Scissors” in Molecular Cell

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, also known as DNA or gene ‘scissors’, which have revolutionized the field of genome editing, enabling scientists to […]
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Visualizing ER-phagy and ER architecture in vivo

ER-phagy is an evolutionarily conserved mechanism crucial for maintaining cellular homeostasis. However, significant gaps persist in our understanding of how ER-phagy and the ER network vary across cell subtypes, tissues, and organs. Furthermore, the pathophysiological relevance of ER-phagy remains poorly elucidated. Addressing these questions requires developing quantifiable methods to visualize ER-phagy and ER architecture in […]
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Worlwide

VU Researchers Publish Study on the Mechanism of CRISPR-Cas “Protein Scissors” in Molecular Cell

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, also known as DNA or gene ‘scissors’, which have revolutionized the field of genome editing, enabling scientists to […]
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Visualizing ER-phagy and ER architecture in vivo

ER-phagy is an evolutionarily conserved mechanism crucial for maintaining cellular homeostasis. However, significant gaps persist in our understanding of how ER-phagy and the ER network vary across cell subtypes, tissues, and organs. Furthermore, the pathophysiological relevance of ER-phagy remains poorly elucidated. Addressing these questions requires developing quantifiable methods to visualize ER-phagy and ER architecture in […]
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Workers and the just transition

Some takes the form of an anti-environmental backlash, instigated or colonised by conservative and far-right forces. While posing as allies of “working families”, they denigrate the most fundamental of workers’ needs: for a habitable planet.  Some takes a progressive form, the classic case being the gilets jaunes in France. When Emmanuel Macron’s government hiked “green […]
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