Admin's articles Biotechnology FDA slaps hold on Denali's plans for phase 1 rare disease trial The FDA has placed a hold on Denali Therapeutics’ plans to launch a phase 1 rare disease trial, citing concerns about immune reactions to the investigational treatment recorded in preclinical mouse studies. Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked Life Sciences Hornet-eating frog shows remarkable venom resistance A frog with an unexpectedly strong resistance to venom has been identified, and it routinely eats hornets despite the insects’ dangerous stingers. Researchers believe this species may become a useful model organism for exploring how animals develop tolerance to venom. For many people, even glimpsing a hornet’s stinger is enough to cause alarm. Yet certain […] Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked Biology High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked Life Sciences Doomed ants send a final scent to save their colony Ant societies behave like tightly integrated “superorganisms,” where thousands of individuals work together in a way that resembles the coordinated activity of cells in a body. Researchers at the Institute of Science and Technology Austria (ISTA) have found that terminally ill ant brood release a distinctive odor, similar to the way infected body cells send […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked Life Sciences A tiny ocean worm just revealed a big secret about how eyes evolve A research team from the University of Vienna and the Alfred Wegener Institute in Bremerhaven has uncovered how the eyes of adult marine bristleworms continue to increase in size throughout their entire lifespan. The work shows that this constant growth is powered by a ring of neural stem cells that resembles similar structures found in […] Written by Admin December 3, 2025December 3, 2025 Saving Bookmark this article Bookmarked Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.b0ed217.1764670323.277f7c81 Written by Admin December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked Life Sciences 242-million-year-old mini predator changes lizard evolution A recently analyzed fossil from Devon is giving scientists a rare look at what the earliest members of the lizard lineage may have looked like, and the findings come with several unexpected twists, according to researchers at the University of Bristol. The work was published in Nature. Today, lizards and their close relatives, including snakes […] Written by Admin December 1, 2025December 1, 2025 Saving Bookmark this article Bookmarked Life Sciences Scientists reveal a hidden alarm system inside your cells Ludwig Maximilian University of Munich (LMU) researchers have uncovered how ribosomes are able to alert the cell when something is wrong. Ribosomes are best known as the cell’s protein builders. They attach to mRNA and travel along it, interpreting the genetic code and linking amino acids to form new proteins. Their role, however, extends beyond […] Written by Admin November 30, 2025November 30, 2025 Saving Bookmark this article Bookmarked Life Sciences A strange ancient foot reveals a hidden human cousin Thanks to newly discovered fossil bones, scientists have now been able to match an enigmatic 3.4-million-year-old hominin foot, first found in 2009, to a species that is different from the famous fossil Lucy. This link strengthens the case that two separate species of early human ancestors were living in the same region at the same […] Written by Admin November 29, 2025November 29, 2025 Saving Bookmark this article Bookmarked Biology Is the Parkinson’s-associated protein TMEM175 a proton channel: Yay or nay? The abnormal protein degradation implicated in the pathogenesis of Parkinson’s disease was previously attributed to defective H+ leakage from lysosomes via TMEM175 (https://doi.org/10.1016/j.cell.2022.05.021). In this issue, Riederer et al. (https://doi.org/10.1083/jcb.202501145) demonstrate that TMEM175 is instead a K+ channel, minimally permeable to H+. Written by Admin November 29, 2025November 29, 2025 Saving Bookmark this article Bookmarked Life Sciences Scientists discover a hidden deep sea hotspot bursting with life Off the coast of Papua New Guinea, scientists have identified a previously unknown type of hydrothermal field where two different processes occur at the same time: hot hydrothermal fluids rise from below the seafloor while unusually large quantities of methane and other hydrocarbons escape from the sediments. This combination has not been documented anywhere else. […] Written by Admin November 28, 2025November 28, 2025 Saving Bookmark this article Bookmarked Life Sciences Archaeologists uncover a 2,000-year-old crop in the Canary Islands Lentils currently cultivated in the Canary Islands have an unbroken local history that reaches back nearly 2,000 years. This remarkable continuity has been revealed by the first genetic analysis of archaeological lentils, conducted by researchers at Linköping University and the University of Las Palmas de Gran Canaria in Spain. Because these lentils have been shaped […] Written by Admin November 27, 2025November 27, 2025 Saving Bookmark this article Bookmarked Loading Load more
Biotechnology FDA slaps hold on Denali's plans for phase 1 rare disease trial The FDA has placed a hold on Denali Therapeutics’ plans to launch a phase 1 rare disease trial, citing concerns about immune reactions to the investigational treatment recorded in preclinical mouse studies. Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked
Life Sciences Hornet-eating frog shows remarkable venom resistance A frog with an unexpectedly strong resistance to venom has been identified, and it routinely eats hornets despite the insects’ dangerous stingers. Researchers believe this species may become a useful model organism for exploring how animals develop tolerance to venom. For many people, even glimpsing a hornet’s stinger is enough to cause alarm. Yet certain […] Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked
Biology High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Life Sciences Doomed ants send a final scent to save their colony Ant societies behave like tightly integrated “superorganisms,” where thousands of individuals work together in a way that resembles the coordinated activity of cells in a body. Researchers at the Institute of Science and Technology Austria (ISTA) have found that terminally ill ant brood release a distinctive odor, similar to the way infected body cells send […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Life Sciences A tiny ocean worm just revealed a big secret about how eyes evolve A research team from the University of Vienna and the Alfred Wegener Institute in Bremerhaven has uncovered how the eyes of adult marine bristleworms continue to increase in size throughout their entire lifespan. The work shows that this constant growth is powered by a ring of neural stem cells that resembles similar structures found in […] Written by Admin December 3, 2025December 3, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.b0ed217.1764670323.277f7c81 Written by Admin December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked
Life Sciences 242-million-year-old mini predator changes lizard evolution A recently analyzed fossil from Devon is giving scientists a rare look at what the earliest members of the lizard lineage may have looked like, and the findings come with several unexpected twists, according to researchers at the University of Bristol. The work was published in Nature. Today, lizards and their close relatives, including snakes […] Written by Admin December 1, 2025December 1, 2025 Saving Bookmark this article Bookmarked
Life Sciences Scientists reveal a hidden alarm system inside your cells Ludwig Maximilian University of Munich (LMU) researchers have uncovered how ribosomes are able to alert the cell when something is wrong. Ribosomes are best known as the cell’s protein builders. They attach to mRNA and travel along it, interpreting the genetic code and linking amino acids to form new proteins. Their role, however, extends beyond […] Written by Admin November 30, 2025November 30, 2025 Saving Bookmark this article Bookmarked
Life Sciences A strange ancient foot reveals a hidden human cousin Thanks to newly discovered fossil bones, scientists have now been able to match an enigmatic 3.4-million-year-old hominin foot, first found in 2009, to a species that is different from the famous fossil Lucy. This link strengthens the case that two separate species of early human ancestors were living in the same region at the same […] Written by Admin November 29, 2025November 29, 2025 Saving Bookmark this article Bookmarked
Biology Is the Parkinson’s-associated protein TMEM175 a proton channel: Yay or nay? The abnormal protein degradation implicated in the pathogenesis of Parkinson’s disease was previously attributed to defective H+ leakage from lysosomes via TMEM175 (https://doi.org/10.1016/j.cell.2022.05.021). In this issue, Riederer et al. (https://doi.org/10.1083/jcb.202501145) demonstrate that TMEM175 is instead a K+ channel, minimally permeable to H+. Written by Admin November 29, 2025November 29, 2025 Saving Bookmark this article Bookmarked
Life Sciences Scientists discover a hidden deep sea hotspot bursting with life Off the coast of Papua New Guinea, scientists have identified a previously unknown type of hydrothermal field where two different processes occur at the same time: hot hydrothermal fluids rise from below the seafloor while unusually large quantities of methane and other hydrocarbons escape from the sediments. This combination has not been documented anywhere else. […] Written by Admin November 28, 2025November 28, 2025 Saving Bookmark this article Bookmarked
Life Sciences Archaeologists uncover a 2,000-year-old crop in the Canary Islands Lentils currently cultivated in the Canary Islands have an unbroken local history that reaches back nearly 2,000 years. This remarkable continuity has been revealed by the first genetic analysis of archaeological lentils, conducted by researchers at Linköping University and the University of Las Palmas de Gran Canaria in Spain. Because these lentils have been shaped […] Written by Admin November 27, 2025November 27, 2025 Saving Bookmark this article Bookmarked
