Activation of lysosomal Ca 2+ channels mitigates mitochondrial damage and oxidative stress Elevated levels of plasma-free fatty acids and oxidative stress have been identified as putative primary pathogenic factors in endothelial dysfunction etiology, though their roles are unclear. In human endothelial cells, we found that saturated fatty acids (SFAs)—including the plasma-predominant palmitic acid (PA)—cause mitochondrial fragmentation and elevation of intracellular reactive oxygen species (ROS) levels. TRPML1 is […] Written by Admin November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Tuberculosis research in 2024: the latest advancements According to a new World Health Organization (WHO) report released on October 29, 2024, tuberculosis (TB) replaced COVID-19 to become the top cause of infectious disease-related deaths in 2023, as a total of 1.25 million people died from it last year. Additionally, 8.2 million people were newly diagnosed, up from 7.5 million in 2022. TB […] Written by Willow Shah-Neville November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Explore the Future of Healthcare: 8 Transformative Trends The healthcare landscape is undergoing a significant transformation driven by technological advancements and evolving medical knowledge. Over the past few years, we’ve identified eight key trends that will profoundly reshape healthcare delivery. While we’ve discussed these trends individually in previous posts, this article aims to provide a comprehensive overview, benefiting both healthcare professionals and users. […] Written by Admin October 12, 2023October 12, 2023 Saving Bookmark this article Bookmarked
Blog Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Blog The Importance of Introducing Science to Children from an Early Age lifesciencenews.info – Science is systematic knowledge about nature and the physical world which discusses physics, chemistry, botany, zoology, geology, and so on. In everyday life, science has a direct and indirect influence. Apart from that, science also provides many benefits in life. Therefore, it is not surprising that science is one of the mandatory subjects […] Written by teteh66335 May 24, 2024May 24, 2024 Saving Bookmark this article Bookmarked
Blog Harinarayan Gopichandran Welcomed as Vice President, Technical Solutions at PointCross Life Sciences PointCross Life Sciences is pleased to announce the appointment of Harinarayan Gopichandran as Vice President, Technical Solutions, marking a significant addition to its leadership team. Hari’s extensive background in statistical programming, gained through roles at Icon Clinical Research, Novartis, Allergan, Cognizant, and Saama, positions him as a notable figure in the industry. In his new […] Written by Admin January 16, 2024January 16, 2024 Saving Bookmark this article Bookmarked
Life Sciences Microbes in mouth reflect lifestyle choices Lifestyle can shape the composition of beneficial bacteria and other microorganisms within the mouth, according to a new study led by Penn State biologists. The international team revealed how the “oral microbiome” differs over a range of subsistence strategies — from nomadic hunter gatherers to farmers to industrialized groups — and found that lifestyle, as […] Written by Admin November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Life Sciences Fossil of huge terror bird offers new information about wildlife in South America 12 million years ago Researchers including a Johns Hopkins University evolutionary biologist report they have analyzed a fossil of an extinct giant meat-eating bird — which they say could be the largest known member of its kind — providing new information about animal life in northern South America millions of years ago. The evidence lies in the leg bone […] Written by Admin November 5, 2024November 5, 2024 Saving Bookmark this article Bookmarked
Biology Detailing organelle division and segregation in Plasmodium falciparum The malaria-causing parasite, P. falciparum, replicates through schizogony, a tightly orchestrated process where numerous daughter parasites are formed simultaneously. Proper division and segregation of one-per-cell organelles, like the mitochondrion and apicoplast, are essential, yet remain poorly understood. We developed a new reporter parasite line that allows visualization of the mitochondrion in blood and mosquito stages. […] Written by Admin November 4, 2024November 4, 2024 Saving Bookmark this article Bookmarked
Life Sciences Microbes in mouth reflect lifestyle choices Lifestyle can shape the composition of beneficial bacteria and other microorganisms within the mouth, according to a new study led by Penn State biologists. The international team revealed how the “oral microbiome” differs over a range of subsistence strategies — from nomadic hunter gatherers to farmers to industrialized groups — and found that lifestyle, as […] Written by Admin November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Life Sciences Fossil of huge terror bird offers new information about wildlife in South America 12 million years ago Researchers including a Johns Hopkins University evolutionary biologist report they have analyzed a fossil of an extinct giant meat-eating bird — which they say could be the largest known member of its kind — providing new information about animal life in northern South America millions of years ago. The evidence lies in the leg bone […] Written by Admin November 5, 2024November 5, 2024 Saving Bookmark this article Bookmarked
Biology Activation of lysosomal Ca 2+ channels mitigates mitochondrial damage and oxidative stress Elevated levels of plasma-free fatty acids and oxidative stress have been identified as putative primary pathogenic factors in endothelial dysfunction etiology, though their roles are unclear. In human endothelial cells, we found that saturated fatty acids (SFAs)—including the plasma-predominant palmitic acid (PA)—cause mitochondrial fragmentation and elevation of intracellular reactive oxygen species (ROS) levels. TRPML1 is […] Written by Admin November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Biotechnology Tuberculosis research in 2024: the latest advancements According to a new World Health Organization (WHO) report released on October 29, 2024, tuberculosis (TB) replaced COVID-19 to become the top cause of infectious disease-related deaths in 2023, as a total of 1.25 million people died from it last year. Additionally, 8.2 million people were newly diagnosed, up from 7.5 million in 2022. TB […] Written by Willow Shah-Neville November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Biology Activation of lysosomal Ca 2+ channels mitigates mitochondrial damage and oxidative stress Elevated levels of plasma-free fatty acids and oxidative stress have been identified as putative primary pathogenic factors in endothelial dysfunction etiology, though their roles are unclear. In human endothelial cells, we found that saturated fatty acids (SFAs)—including the plasma-predominant palmitic acid (PA)—cause mitochondrial fragmentation and elevation of intracellular reactive oxygen species (ROS) levels. TRPML1 is […] Written by Admin November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Biotechnology Tuberculosis research in 2024: the latest advancements According to a new World Health Organization (WHO) report released on October 29, 2024, tuberculosis (TB) replaced COVID-19 to become the top cause of infectious disease-related deaths in 2023, as a total of 1.25 million people died from it last year. Additionally, 8.2 million people were newly diagnosed, up from 7.5 million in 2022. TB […] Written by Willow Shah-Neville November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked