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SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity

The gene encoding superoxide dismutase 1 (SOD1) is often mutated in familial amyotrophic lateral sclerosis (ALS), affecting motor neurons. Compared with ALS-associated mutant SOD1, the function of WT SOD1 is less explored. We demonstrate that during starvation, WT and mutant SOD1 are transported into lysosomes. Genome-wide CRISPR interference (CRISPRi) screening identified autophagy-related proteins and the […]
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Military diverting critical materials from renewables

A huge amount of critical mineral mining is ‘not essential’ for the green transition, new analysis from the UK-based campaigning organisation Global Justice Now has found.  The analysis has today been published in a new report, titled ‘Material realities: who needs critical minerals and at whose expense?’. Global Justice Now is demanding the UK government […]
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Explore the Future of Healthcare: 8 Transformative Trends

The healthcare landscape is undergoing a significant transformation driven by technological advancements and evolving medical knowledge. Over the past few years, we’ve identified eight key trends that will profoundly reshape healthcare delivery. While we’ve discussed these trends individually in previous posts, this article aims to provide a comprehensive overview, benefiting both healthcare professionals and users. […]
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Create Your Tailored Rubber Stamps Online Using Our Simple Tool for Any Size and Logo – Contact Us Today!

Design Your Rubber Stamps Online with Our Easy-to-Use Tool for Any Size and Logo – Connect with Us Today! Making Your Unique Rubber Stamp on the Web Creating a personalized rubber stamp has never been simpler in the digital era. With the availability of online rubber stamp makers, you can create your own unique designs […]
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Make Your Unique Custom Rubber Stamps via Our User-Friendly Online Tool for Any Size and Logo – Reach Out to Us Today!

Build Your Own Tailored Rubber Stamps on the Web with Our Easy Tool for Any Size and Logo – Contact Us Right Away! Making Your Unique Rubber Stamp on the Web In today’s digital age, making a custom rubber stamp is easier than ever. The rise of online rubber stamp tools allows you to make […]
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Start Making Your Digital Stamp Now: How to Decide on the Size, Layout, and Shape for Any PNG and Save It

Kick Off Your Online Stamp Creation Now: How to Pick the Right Size, Layout, and Shape for Any Digital PNG and Save It Create Your Own Unique Design with an Online Stamp Maker An online stamp maker makes it simple to create a personalized stamp. With just a few clicks, you can start designing your […]
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Scientists just cracked the code to editing entire chromosomes flawlessly
  1. Life Sciences

Scientists just cracked the code to editing entire chromosomes flawlessly

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems. The study, published online in Cell on August 4, achieves multiple types of precise DNA manipulations […]
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  1. Biology

Disordered Interfacial Water Boosts Electrochemical C–C Coupling

In the relentless pursuit to combat climate change, the electrochemical conversion of carbon dioxide (CO₂) and carbon monoxide (CO) into value-added, energy-rich multi-carbon products has emerged as a beacon of hope. These processes promise not only to mitigate greenhouse gas emissions but also to create sustainable fuel alternatives that could revolutionize the energy landscape. However, […]
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DNA from the deep reveals a hidden ocean “superhighway”
  1. Life Sciences

DNA from the deep reveals a hidden ocean “superhighway”

A world-first study led by Museums Victoria Research Institute has revealed that beneath the cold, dark, pressurized world of the deep sea, marine life is far more globally connected than previously imagined. Published on July 23 in Nature, this landmark study maps the global distribution and evolutionary relationships of brittle stars (Ophiuroidea), the ancient, spiny animals […]
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Scientists just cracked the code to editing entire chromosomes flawlessly
  1. Life Sciences

Scientists just cracked the code to editing entire chromosomes flawlessly

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems. The study, published online in Cell on August 4, achieves multiple types of precise DNA manipulations […]
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  1. Biology

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity

The gene encoding superoxide dismutase 1 (SOD1) is often mutated in familial amyotrophic lateral sclerosis (ALS), affecting motor neurons. Compared with ALS-associated mutant SOD1, the function of WT SOD1 is less explored. We demonstrate that during starvation, WT and mutant SOD1 are transported into lysosomes. Genome-wide CRISPR interference (CRISPRi) screening identified autophagy-related proteins and the […]
Written by
  1. Environmental Science

Military diverting critical materials from renewables

A huge amount of critical mineral mining is ‘not essential’ for the green transition, new analysis from the UK-based campaigning organisation Global Justice Now has found.  The analysis has today been published in a new report, titled ‘Material realities: who needs critical minerals and at whose expense?’. Global Justice Now is demanding the UK government […]
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  1. Biology

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity

The gene encoding superoxide dismutase 1 (SOD1) is often mutated in familial amyotrophic lateral sclerosis (ALS), affecting motor neurons. Compared with ALS-associated mutant SOD1, the function of WT SOD1 is less explored. We demonstrate that during starvation, WT and mutant SOD1 are transported into lysosomes. Genome-wide CRISPR interference (CRISPRi) screening identified autophagy-related proteins and the […]
Written by
  1. Environmental Science

Military diverting critical materials from renewables

A huge amount of critical mineral mining is ‘not essential’ for the green transition, new analysis from the UK-based campaigning organisation Global Justice Now has found.  The analysis has today been published in a new report, titled ‘Material realities: who needs critical minerals and at whose expense?’. Global Justice Now is demanding the UK government […]
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