Biotechnology

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  1. Biotechnology

Excipient Use in Biopharmaceuticals: Key Insights – ChemIntel360

Originally published at Get our excipient business reports at and our drug patent reports at https://chemintel360.com/product-category/drug-patent-reports/ The biopharmaceutical industry has witnessed significant advancements over the past few decades, with excipients playing a crucial role in the formulation and stability of therapeutic drugs. Excipients, often considered the unsung heroes of drug development, are essential components that […]
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A new era in immunotherapy
  1. Biotechnology

A new era in immunotherapy

Cancer vaccines represent an increasingly important area of biotech in oncology, using the body’s immune system to combat cancer cells. They are broadly categorized into two types: preventive and therapeutic vaccines. Preventive vaccines are designed to avert cancer development by targeting infections that can lead to cancer. Some examples of these are human papillomavirus (HPV) […]
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Cradle Secures $73m Series B to Accelerate AI-Driven Protein Engineering
  1. Biotechnology

Cradle Secures $73m Series B to Accelerate AI-Driven Protein Engineering

Cradle, the pioneering platform for AI-powered protein engineering in Amsterdam, Netherlands, has successfully raised US$73m in Series B funding. The round, led by IVP with participation from existing investors Index Ventures and Kindred Capital, brings the company’s total funding to over US$100m. Cradle’s generative AI platform is already used across multiple industries, including pharmaceuticals, agriculture, […]
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New tentative approval for Alembic drug dabigatran etexilate mesylate
  1. Biotechnology

Which pharmaceutical drugs have the most drug patents in United Kingdom?

Copyright © DrugPatentWatch. Originally published at https://www.drugpatentwatch.com/blog/ This chart shows the drugs with the most patents in United Kingdom. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired. The companies with the greatest patent coverage in United Kingdom are: Onzetra Xsail Xhance Evzio Evzio (autoinjector) […]
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Six bispecific antibody companies you should know about
  1. Biotechnology

Six bispecific antibody companies you should know about

Bispecific antibodies seem to be all the rage at the minute. Their ability to deliver targeted therapeutics to patients with a two-in-one approach by simultaneously binding to two different antigens or epitopes makes them an extremely attractive proposition to drug developers. This can be seen in the fact that there have been multiple big buyouts […]
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Tetraspecific B/NK cell better than T cell engagers
  1. Biotechnology

Tetraspecific B/NK cell better than T cell engagers

The therapeutic landscape for relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) is evolving toward targeted T-cell based immunotherapies, including CD19-targeted CAR-T and CD3xCD20 T-cell engaging (TCE) bispecificantibodies. Yet, there remains an unmet medical need for patients who are refractory to, or ineligible for these treatments. Leveraging natural killer NK cells emerges as a promising […]
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New tentative approval for Alembic drug dabigatran etexilate mesylate
  1. Biotechnology

New tentative approval for Alembic drug dabigatran etexilate mesylate

Copyright © DrugPatentWatch. Originally published at https://www.drugpatentwatch.com/blog/ Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs. There are three patents protecting this compound. Drug patent litigation for DABIGATRAN ETEXILATE MESYLATE. Nine suppliers are […]
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Good Reads

Mitochondrial presequences harbor variable strengths to maintain organellar function

Hundreds of mitochondrial proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphiphilic helices, presequences lack a consensus motif and thus likely promote protein import into mitochondria with variable efficiencies. Indeed, the concept of presequence strength underlies biological models such as stress sensing, yet a quantitative analysis of […]
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Worlwide

Mitochondrial presequences harbor variable strengths to maintain organellar function

Hundreds of mitochondrial proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphiphilic helices, presequences lack a consensus motif and thus likely promote protein import into mitochondria with variable efficiencies. Indeed, the concept of presequence strength underlies biological models such as stress sensing, yet a quantitative analysis of […]
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Labour’s ‘deeply alarming’ attack on protest rights

British authorities have severely restricted the right to protest in contravention of their international human rights obligations, creating an environment in which peaceful dissent is increasingly treated as a criminal act, Human Rights Watch said in its latest report. ‘Silencing the Streets’: The Right to Protest Under Attack in the UK documents that the UK’s […]
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