Biotechnology

Ancient Root Development Gene Predates Roots Themselves
  1. Biotechnology

Ancient Root Development Gene Predates Roots Themselves

In a groundbreaking study published in the journal New Phytologist, researchers at Kobe University have unveiled a remarkable discovery that deepens our understanding of plant evolution and organ development. The team, led by esteemed plant biologist FUKAKI Hidehiro, revealed that a gene previously known to regulate root development in vascular plants is also critically involved […]
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Countdown to SLAS Europe: NestEgg Labs BV
  1. Biotechnology

Countdown to SLAS Europe: NestEgg Labs BV

Founded in 2022 by Tanner Carden (CEO) and Hans Keijdener, Maastricht-based start-up NestEgg Labs BV focuses on developing interoperable automation systems for cell culture that reduce manual intervention, improve workflow reproducibility, and limit plastics waste. At the core of NestEgg’s offering is Ovation, a smart incubator platform designed to automate key stages of the cell […]
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Detecting Radiation Esophagitis Using 18F-FAPI-04 PET
  1. Biotechnology

Detecting Radiation Esophagitis Using 18F-FAPI-04 PET

In a groundbreaking development in oncology imaging, researchers have unveiled the potential of a novel positron emission tomography/computed tomography (PET/CT) tracer, ^18F-FAPI-04, to sensitively detect radiation esophagitis (RE) in patients suffering from locally advanced esophageal squamous cell carcinoma (LA-ESCC). This investigation, recently published in BMC Cancer, represents a significant leap forward in non-invasive monitoring of […]
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Countdown to SLAS Europe: Minos Biosciences SAS
  1. Biotechnology

Countdown to SLAS Europe: Minos Biosciences SAS

Paris-based Minos Biosciences SAS’ (www.minos.bio) mission is to improve the understanding and treatment of complex diseases such as cancer, infectious and autoimmune diseases. As AI-powered drug discovery and therapeutic innovation holds great promise, the company’s MinoSuiteTM integrated cell analysis platform creates unprecedented multimodal datasets that will offer direct, ground-truth labels for AI training, opening  up […]
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Harnessing Neddylation-Targeted Therapies to Usher in a New Era of Liver
  1. Biotechnology

Harnessing Neddylation-Targeted Therapies to Usher in a New Era of Liver

Hepatocellular carcinoma (HCC), the predominant form of primary liver cancer, continues to challenge the global healthcare landscape. Despite significant advances in oncology, the prognosis for HCC remains dismal, largely due to late diagnoses, aggressive tumor behavior, and limited effective treatment modalities. Emerging research, however, has identified a critical cellular mechanism that may redefine therapeutic strategies: […]
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Good Reads

Mammals didn't walk upright until late—here's what fossils reveal

Mammals didn’t walk upright until late—here’s what fossils reveal

For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […]
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A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores

Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […]
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Worlwide

Mammals didn't walk upright until late—here's what fossils reveal

Mammals didn’t walk upright until late—here’s what fossils reveal

For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […]
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A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores

Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […]
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