Biotechnology The genomics layoff wave in the US Newsletter Signup – Under Article / In Page “*” indicates required fields Just five months into 2025, and a string of layoffs has already come down on the genomics space. More than 25 genomics companies have shed several workers since the year began, many of them facing the brunt of a financial downturn. Prime Medicine […] Written by Roohi Mariam Peter May 22, 2025May 22, 2025 Saving Bookmark this article Bookmarked
Biotechnology Countdown to SLAS Europe: NestEgg Labs BV Founded in 2022 by Tanner Carden (CEO) and Hans Keijdener, Maastricht-based start-up NestEgg Labs BV focuses on developing interoperable automation systems for cell culture that reduce manual intervention, improve workflow reproducibility, and limit plastics waste. At the core of NestEgg’s offering is Ovation, a smart incubator platform designed to automate key stages of the cell […] Written by Thomas Gabrielczyk May 19, 2025May 19, 2025 Saving Bookmark this article Bookmarked
Biotechnology A bespoke CRISPR therapy suggests a blueprint for treating ‘N-of-1’ diseases A gene editing drug custom-made for a critically ill baby showed that, for some ultra-rare diseases, it’s possible to design and test a new CRISPR medicine in just a few months. Written by Ben Fidler May 15, 2025May 15, 2025 Saving Bookmark this article Bookmarked
Biotechnology Detecting Radiation Esophagitis Using 18F-FAPI-04 PET In a groundbreaking development in oncology imaging, researchers have unveiled the potential of a novel positron emission tomography/computed tomography (PET/CT) tracer, ^18F-FAPI-04, to sensitively detect radiation esophagitis (RE) in patients suffering from locally advanced esophageal squamous cell carcinoma (LA-ESCC). This investigation, recently published in BMC Cancer, represents a significant leap forward in non-invasive monitoring of […] Written by Bioengineer May 12, 2025May 12, 2025 Saving Bookmark this article Bookmarked
Biotechnology the power of TLR agonists Newsletter Signup – Under Article / In Page “*” indicates required fields In the vast field of immunotherapy, toll-like receptor agonists (TLR) emerged as powerful catalysts to boost the immune system. This class of drugs is designed to mimic the body’s natural defense mechanisms and target a spectrum of diseases – from cancer and infectious […] Written by Roohi Mariam Peter May 9, 2025May 9, 2025 Saving Bookmark this article Bookmarked
Biotechnology Countdown to SLAS Europe: Minos Biosciences SAS Paris-based Minos Biosciences SAS’ (www.minos.bio) mission is to improve the understanding and treatment of complex diseases such as cancer, infectious and autoimmune diseases. As AI-powered drug discovery and therapeutic innovation holds great promise, the company’s MinoSuiteTM integrated cell analysis platform creates unprecedented multimodal datasets that will offer direct, ground-truth labels for AI training, opening up […] Written by Thomas Gabrielczyk May 5, 2025May 5, 2025 Saving Bookmark this article Bookmarked
Biotechnology Moderna combination flu, COVID shot delayed amid FDA scrutiny Additional data required by the FDA are the latest evidence of what one analyst described as a “higher bar” for vaccines. Written by Delilah Alvarado May 2, 2025May 2, 2025 Saving Bookmark this article Bookmarked
Biotechnology Harnessing Neddylation-Targeted Therapies to Usher in a New Era of Liver Hepatocellular carcinoma (HCC), the predominant form of primary liver cancer, continues to challenge the global healthcare landscape. Despite significant advances in oncology, the prognosis for HCC remains dismal, largely due to late diagnoses, aggressive tumor behavior, and limited effective treatment modalities. Emerging research, however, has identified a critical cellular mechanism that may redefine therapeutic strategies: […] Written by Bioengineer April 29, 2025April 29, 2025 Saving Bookmark this article Bookmarked
Biotechnology The past, present, and future of genome sequencing Newsletter Signup – Under Article / In Page “*” indicates required fields Genome sequencing is the process of determining the complete DNA sequence of an organism’s genome, a step-by-step decoding of all the genetic instructions. In humans, that means reading around 3 billion base pairs to reveal everything from disease risk and drug response to […] Written by Jules Adam April 25, 2025April 25, 2025 Saving Bookmark this article Bookmarked
Biotechnology Whey Waste Finds New Life as Protein Paris-based start-up Standing Ovation’s patented process converts the serums supplied by Bel into functional casein proteins. The approach offers a sustainable alternative to conventional dairy supply chains. Bel hopes that, in addition to reducing waste and creating an additional valorisation stream, it will also promote a circular economy within the industry. “Thanks to this process, […] Written by Uta Mommert April 22, 2025April 22, 2025 Saving Bookmark this article Bookmarked
Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis Faithful chromosome segregation requires proper function of the mitotic spindle, which is built from, and depends on, the coordinated regulation of many microtubules and the activities of molecular motors and MAPs. In addition, microtubules themselves are assembled from multiple variants, or isotypes of α- and β-tubulin, yet whether they mediate the activities of motors and […] Written by Admin July 28, 2025July 28, 2025 Saving Bookmark this article Bookmarked
DO NOT PUBLISH /// Seeding ecofeminism in Rojava In 2012, a year after the civil war began in the rest of the country, Kurdish forces took advantage of the withdrawal of Bashar al-Assad’s troops from some northeastern areas to establish a form of political autonomy. Struggles People locally say that the move towards autonomy has been influenced by the ideas of Abdullah Öcalan, […] Written by brendan July 28, 2025July 28, 2025 Saving Bookmark this article Bookmarked
Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis Faithful chromosome segregation requires proper function of the mitotic spindle, which is built from, and depends on, the coordinated regulation of many microtubules and the activities of molecular motors and MAPs. In addition, microtubules themselves are assembled from multiple variants, or isotypes of α- and β-tubulin, yet whether they mediate the activities of motors and […] Written by Admin July 28, 2025July 28, 2025 Saving Bookmark this article Bookmarked
DO NOT PUBLISH /// Seeding ecofeminism in Rojava In 2012, a year after the civil war began in the rest of the country, Kurdish forces took advantage of the withdrawal of Bashar al-Assad’s troops from some northeastern areas to establish a form of political autonomy. Struggles People locally say that the move towards autonomy has been influenced by the ideas of Abdullah Öcalan, […] Written by brendan July 28, 2025July 28, 2025 Saving Bookmark this article Bookmarked
Leads Biolabs hits Hong Kong stock exchange in $189M IPO Chinese biotech company Leads Biolabs has hit the Hong Kong stock exchange, snagging $189 million through an initial public offering on the HKEX. The Nanjing-based antibody aficionado plans to use the windfall first and foremost on clinical trials, the company said in a July 24 release. About $123 million will go to clinical research, with […] Written by Darren Incorvaia July 28, 2025July 28, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked