Biotechnology

Calluna Pharma starts efficacy test with unique IPF antibody
  1. Biotechnology

Calluna Pharma starts efficacy test with unique IPF antibody

Among the 110 drug development programmes currently underway worldwide targeting the US$4.5bn IPF market,  Calluna Pharma‘s IgG1 antibody directed against the damage-associated molecular pattern (DAMP) protein S100A4 stands out for its unique mechanism of action. Preclinical studies demonstrated selective inhibition of both fibroblast activation and pro-fibrotic inflammation, alongside a favourable safety and immunogenicity profile, which […]
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Oxygen Dilemma: Balancing Life’s Vital Element
  1. Biotechnology

Oxygen Dilemma: Balancing Life’s Vital Element

Oxygen: The Dual-Edged Sword that Sustains and Challenges Life Oxygen, the most abundant element on Earth’s surface, is undeniably the cornerstone of life as we understand it. It powers the metabolic engines of almost all complex organisms, enabling the biochemical reactions that sustain life’s intricate processes. Yet, despite its vital role, oxygen’s influence is paradoxical […]
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Dewpoint Tx' current pipeline
  1. Biotechnology

Dewpoint Therapeutics cuts workforce, refocuses pipeline

Despite securing US$287m from 16 investors across three funding rounds—US$60m (Series A, 2019), US$77m (Series B, 2020), and US$150m (Series C, 2022)—the firm cited a high burn rate as the reason for scaling back. Dewpoint will now prioritise clinical development of its lead candidate, DPTx3186, a beta-catenin inhibitor targeting the WNT signalling pathway, in gastric […]
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Advancing Microplastic Quantification with NMR Spectroscopy
  1. Biotechnology

Advancing Microplastic Quantification with NMR Spectroscopy

In the ever-evolving battle against plastic pollution, researchers are turning to increasingly sophisticated analytical techniques to quantify and characterize microplastics. A groundbreaking study published in Microplastics & Nanoplastics offers compelling evidence that nuclear magnetic resonance (NMR) spectroscopy could transform the way scientists detect and measure these pervasive contaminants. By leveraging the nuanced molecular insights provided […]
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FDA Launches the TEMPO Pilot for Digital Health Devices to Improve Patient Access to Technologies – Duane Morris Life Sciences Law

By Vicki G. Norton, Ph.d., Frederick R. Ball and Victoria (Tori) Hawekotte The U.S. Food and Drug Administration has announced the Technology-Enabled Meaningful Patient Outcomes (TEMPO) for Digital Health Devices Pilot, through which FDA would exercise enforcement discretion over participant manufacturers’ digital health devices to improve patient access to digital health […]
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FDA Launches the TEMPO Pilot for Digital Health Devices to Improve Patient Access to Technologies – Duane Morris Life Sciences Law

By Vicki G. Norton, Ph.d., Frederick R. Ball and Victoria (Tori) Hawekotte The U.S. Food and Drug Administration has announced the Technology-Enabled Meaningful Patient Outcomes (TEMPO) for Digital Health Devices Pilot, through which FDA would exercise enforcement discretion over participant manufacturers’ digital health devices to improve patient access to digital health […]
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New Arabidopsis BIK1 Alleles Confirm Immunity Role

In a groundbreaking study poised to redefine our understanding of plant immunity, researchers have unveiled novel insights into the pivotal roles of the receptor-like cytoplasmic kinases BIK1 and PBL1 in Arabidopsis. These kinases, previously studied primarily through single transfer DNA (T-DNA) insertional mutant alleles, are reaffirmed as central players in the plant’s pattern-triggered immunity (PTI) […]
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