Clinical

  1. Clinical

New Research Reveals Novel Neuroprotective Drug Candidate Meets Main Endpoint in Sufferers with Gentle to Average Alzheimer’s Illness

NEW YORK, Could 17, 2024. A examine revealed in the present day in Nature Drugs discovered {that a} novel neuroprotective drug candidate, LM11A-31, was secure and well-tolerated following dosing for 26 weeks in sufferers with gentle to reasonable Alzheimer’s illness. LM11A-31 additionally slowed the development of a number of spinal fluid and imaging biomarkers. These […]
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Geisinger enrolls first affected person in amyloid cardiomyopathy trial

DANVILLE, Pa., Could 10, 2024. Heart specialist Brendan Carry, MD, and a workforce of Geisinger physicians have enrolled the primary affected person within the U.S. right into a cardiac amyloidosis trial. The workforce can also be the primary to within the U.S. to display screen for the trial. “If a affected person qualifies for the […]
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Constructive topline outcomes of Section 2 head and neck most cancers trial with lead NOX inhibitor candidate, setanaxib

STOCKHOLM, Could 6, 2024. Calliditas Therapeutics AB (“Calliditas”) at present introduced knowledge from the proof-of-concept Section 2 trial evaluating setanaxib, its lead NOX enzyme inhibitor, together with pembrolizumab, in sufferers with squamous cell carcinoma of the top and neck (SCCHN). The evaluation confirmed statistically important enhancements in progression-free survival (PFS), in addition to in total […]
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Decrease Dose of Mpox Vaccine is Secure and Generates Six-Week Antibody Response Equal to Commonplace Routine

April 27, 2024 — A dose-sparing intradermal mpox vaccination routine was protected and generated an antibody response equal to that induced by the usual routine at six weeks (two weeks after the second dose), based on findings offered immediately on the European Society of Scientific Microbiology and Infectious Ailments World Congress in Barcelona. The outcomes […]
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FDA Approves Scientific Trial for GFH925 Monotherapy in Section III Registrational Research Treating Metastatic Colorectal Most cancers

SHANGHAI, April 19, 2024. GenFleet Therapeutics, a clinical-stage biotechnology firm specializing in cutting-edge therapies in oncology and immunology, introduced US Meals and Drug Administration (FDA) has granted the medical trial approval for GFH925 (KRAS G12C inhibitor) in a multi-center, open-label, randomized and managed section III examine treating refractory metastatic colorectal most cancers (CRC) sufferers. It’s […]
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TLX101-CDx (Pixclara) Granted FDA Quick Monitor Designation

Melbourne (Australia) | 16 April 2024 — Telix right this moment proclaims that america (U.S.) Meals and Drug Administration (FDA) has granted Quick Monitor designation1 for the Firm’s investigational glioma imaging product, TLX101-CDx (Pixclara™2, 18F-floretyrosine or 18F-FET). The granted Quick Monitor designation is for the characterisation of progressive or recurrent glioma utilizing positron emission […]
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NRx Prescribed drugs Pronounces Information-Lock of Part 2b/3 Trial of NRX-101 in Suicidal Therapy Resistant Bipolar Despair

RADNOR, Pa., April 8, 2024. NRx Prescribed drugs, Inc. (“NRx Prescribed drugs”, the “Firm”), a clinical-stage biopharmaceutical firm, at this time introduced that the Firm has achieved data-lock in its Part 2b/3 Suicidal Therapy Resistant Bipolar Despair Research with NRX-101. With data-lock, as forecast in final week’s earnings name, the whole information set handed on […]
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Amylyx Prescribed drugs Publicizes Interim Information From Ongoing Part 2 HELIOS Scientific Trial Demonstrating Enhancements in Pancreatic Operate and Glycemic Management with AMX0035 in Individuals with Wolfram Syndrome

CAMBRIDGE, Mass.–(BUSINESS WIRE) April 10, 2024 — Amylyx Prescribed drugs, Inc. (NASDAQ: AMLX) (“Amylyx” or the “Firm”) immediately introduced interim information from the continued Part 2 HELIOS scientific trial of AMX0035 (sodium phenylbutyrate [PB] and taurursodiol [TURSO, also known as ursodoxicoltaurine]) in adults dwelling with Wolfram syndrome, a uncommon, progressive genetic illness impacting roughly 3,000 […]
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Cadrenal Therapeutics Receives FDA Orphan Drug Designation for Tecarfarin for Prevention of Thromboembolism and Thrombosis in Sufferers with LVADs, RVADs, Biventricular Help Gadgets, and Whole Synthetic Hearts

PONTE VEDRA, Fla., April 9, 2024 — Cadrenal Therapeutics, Inc. (Nasdaq: CVKD), a biopharmaceutical firm growing tecarfarin, a late-stage novel oral and reversible anticoagulant (blood thinner) designed to forestall coronary heart assaults, strokes, and deaths as a consequence of blood clots in sufferers with uncommon cardiovascular circumstances, introduced immediately that the USA Meals and Drug […]
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First-Affected person Dosed in Part 2 Scientific Examine Evaluating NBI-1070770 in Adults with Main Depressive Dysfunction

SAN DIEGO, April 3, 2024. Neurocrine Biosciences, Inc. right this moment introduced that the primary affected person has been randomized for its Part 2 scientific research to judge the efficacy, security, and tolerability of investigational compound NBI-1070770 in adults with main depressive dysfunction. NBI-1070770 is a novel, selective, and orally energetic, unfavorable allosteric modulator (NAM) […]
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