Life Sciences Once-endangered Kirtland’s warblers show extensive signs of inbreeding in genome The genome of a once-endangered songbird shows extensive signs of inbreeding, according to a new study by Penn State researchers. Because inbreeding can negatively impact survival and reproduction, the results could guide continuing conservation efforts for Kirtland’s warblers, whose populations still rely on extensive management. The new study, published Dec. 9 in the journalEvolutionary Applications, […] Written by Admin December 11, 2024December 11, 2024 Saving Bookmark this article Bookmarked
Life Sciences Insect genome offers insights into rare biological conditions, agricultural biosecurity Lice live their entire lives with a set of genes that in humans would indicate a late-stage degenerative disorder such as Parkinson’s or Alzheimer’s disease. How do lice tolerate this genome structure that in humans and many other animals would result in major neurodegenerative problems? “We’re a long way from connecting those dots,” said Stephen […] Written by Admin December 10, 2024December 10, 2024 Saving Bookmark this article Bookmarked
Life Sciences Close encounters between distant DNA regions cause bursts of gene activity Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, the researchers showed that the folding and movement of DNA, as well as the accumulation of certain proteins, changes depending on whether a gene is active […] Written by Admin December 9, 2024December 9, 2024 Saving Bookmark this article Bookmarked
Life Sciences Single mutation in H5N1 influenza surface protein could enable easier human infection A single modification in the protein found on the surface of the highly pathogenic avian influenza (HPAI) H5N1 influenza virus currently circulating in U.S. dairy cows could allow for easier transmission among humans, according to new research funded by the National Institutes of Health (NIH) and published today in the journal Science. The study results […] Written by Admin December 8, 2024December 8, 2024 Saving Bookmark this article Bookmarked
Life Sciences Conservation paradox: Invasive species are often threatened in their native range Non-native species introduced by humans are among the main causes of global species decline – they were partly responsible for 60 percent of the species that have become extinct worldwide in recent decades. In Central Europe, non-native mammals include species such as the Norway rat, the mouflon and the mink. Now a study led by […] Written by Admin December 7, 2024December 7, 2024 Saving Bookmark this article Bookmarked
Life Sciences From one gene switch, many possible outcomes The University of Pennsylvania’s Aman Husbands, of the School of Arts & Sciences, uncovered surprising ways transcription factors, the genetic switches for genes, regulate plant development. Their findings reveal how subtle changes in a lipid-binding region called the START domain can dramatically alter gene regulation, paving the way for advancements in crop engineering, synthetic biology, […] Written by Admin December 6, 2024December 6, 2024 Saving Bookmark this article Bookmarked
Life Sciences Mammoth as key food source for ancient Americans Scientists have uncovered the first direct evidence that ancient Americans relied primarily on mammoth and other large animals for food. Their research sheds new light on both the rapid expansion of humans throughout the Americas and the extinction of large ice age mammals. The study, featured on the Dec. 4 cover of the journal Science […] Written by Admin December 5, 2024December 5, 2024 Saving Bookmark this article Bookmarked
Life Sciences Backyard chickens are here to stay Chickens have been a mainstay in Australian backyards for generations. New research from the University of Adelaide reveals that owners see their chooks as a blend between pet and livestock as well as a trustworthy source of food. “Our research indicated that backyard chickens are seen as both companion animals and as a source of […] Written by Admin December 4, 2024December 4, 2024 Saving Bookmark this article Bookmarked
Life Sciences Feeding grazing cattle seaweed cuts methane emissions by almost 40% Seaweed is once again showing promise for making cattle farming more sustainable. A new study by researchers at the University of California, Davis, found that feeding grazing beef cattle a seaweed supplement in pellet form reduced their methane emissions by almost 40% without affecting their health or weight. The study was published today (Dec. 2) […] Written by Admin December 3, 2024December 3, 2024 Saving Bookmark this article Bookmarked
Life Sciences Structural link for initiation of protein synthesis in bacteria Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has been a visual mystery: scientists previously did not know how the ribosome attaches to and […] Written by Admin December 2, 2024December 2, 2024 Saving Bookmark this article Bookmarked
A proteome-wide yeast degron collection for the dynamic study of protein function Genome-wide collections of yeast strains, known as libraries, revolutionized the way systematic studies are carried out. Specifically, libraries that involve a cellular perturbation, such as the deletion collection, have facilitated key biological discoveries. However, short-term rewiring and long-term accumulation of suppressor mutations often obscure the functional consequences of such perturbations. We present the AID library […] Written by Admin December 19, 2024December 19, 2024 Saving Bookmark this article Bookmarked
Columbia Climate School Hosts Ninth Annual Sustainability Careers Reception – State of the Planet Practitioners who attended the 2024 Sustainability Careers Reception. (*See below for names and affiliations) Last month, the Columbia Climate School hosted its ninth annual Sustainability Careers Reception at the Columbia Club in Midtown Manhattan. Thirty-three sustainability professionals and 88 Columbia students from varying backgrounds and degree pursuits gathered to discuss the ever-pressing challenges and real-world […] Written by Guest December 19, 2024December 19, 2024 Saving Bookmark this article Bookmarked
A proteome-wide yeast degron collection for the dynamic study of protein function Genome-wide collections of yeast strains, known as libraries, revolutionized the way systematic studies are carried out. Specifically, libraries that involve a cellular perturbation, such as the deletion collection, have facilitated key biological discoveries. However, short-term rewiring and long-term accumulation of suppressor mutations often obscure the functional consequences of such perturbations. We present the AID library […] Written by Admin December 19, 2024December 19, 2024 Saving Bookmark this article Bookmarked
Columbia Climate School Hosts Ninth Annual Sustainability Careers Reception – State of the Planet Practitioners who attended the 2024 Sustainability Careers Reception. (*See below for names and affiliations) Last month, the Columbia Climate School hosted its ninth annual Sustainability Careers Reception at the Columbia Club in Midtown Manhattan. Thirty-three sustainability professionals and 88 Columbia students from varying backgrounds and degree pursuits gathered to discuss the ever-pressing challenges and real-world […] Written by Guest December 19, 2024December 19, 2024 Saving Bookmark this article Bookmarked
Conserving high-elevation grasslands in Peru is key to protect Andean bears Andean bears carefully select the best foraging locations and plants to maximize nutrition and avoid livestock, according to a study publishing December 18, 2024, in the open-access journal PLOS ONE by Nicholas Pilfold at the San Diego Zoo Wildlife Alliance in California, U.S., and colleagues. Andean bears, also known as ‘spectacled bears’ because of the […] Written by Admin December 19, 2024December 19, 2024 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked