Life Sciences How madagascar’s lizards became the island’s last hope for reforestation After the island of Madagascar drifted away from India 88 million years ago, isolating it from all other landmasses, its flora and fauna evolved in seclusion. As these transformed into plants and animals completely unique to their island, Madagascar became a biodiversity hotspot unlike anywhere else on Earth. An important facet of this biodiversity is […] Written by Admin June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Life Sciences What a dinosaur ate 100 million years ago—Preserved in a fossilized time capsule Plant fossils found in the abdomen of a sauropod support the long-standing hypothesis that these dinosaurs were herbivores, finds a study published on June 9 in the Cell Press journal Current Biology. The dinosaur, which was alive an estimated 94 to 101 million years ago, ate a variety of plants and relied almost entirely on […] Written by Admin June 10, 2025June 10, 2025 Saving Bookmark this article Bookmarked
Life Sciences Take Care When Paying Volume-Based Compensation to Sales Agents to Avoid Anti-Kickback Statute Violations – Duane Morris Life Sciences Law By Frederick R. Ball, Coleen W. Hill and Victoria (Tori) Hawekotte Pharmaceutical companies sometimes compensate sales agents per volume sold. The Fifth and Seventh Circuits have indicated that a company may structure such arrangements without running afoul of the Anti-Kickback Statute (AKS). However, such arrangements carry risk of violating the AKS and should […] Written by Duane Morris June 9, 2025June 9, 2025 Saving Bookmark this article Bookmarked
Life Sciences Satellite tracking of 12,000 marine animals reveals ocean giants are in trouble A sweeping new study is helping pinpoint where whales, sharks, turtles, and other ocean giants need the most protection and where current efforts fall short. Led by Ana Sequeira of Australian National University and supported by the United Nations, the research synthesized data from 12,000 satellite-tracked animals across more than 100 species. It reveals how […] Written by Admin June 8, 2025June 8, 2025 Saving Bookmark this article Bookmarked
Life Sciences Extreme weather is wiping out amphibians—Here’s where it’s worst The fire salamander native to Europe is one of many species that depend on sufficient moisture. Credit: Daniel Rosengren/Frankfurt Zoological Society Habitat loss, diseases, pollution, and climate change are already massively affecting amphibians – frogs, salamanders, and the caecilians native to tropical regions. The new study from the Institute for Ecology, Evolution and Diversity shows […] Written by Admin June 7, 2025June 7, 2025 Saving Bookmark this article Bookmarked
Life Sciences Long shot science leads to revised age for land-animal ancestor In 1984, an amateur paleontologist in Scotland found a remarkable specimen: a nearly complete fossil of what looked to be a lizard or salamander. Rather small in size at 20 centimeters, it would turn out to be a crucial piece in the puzzle of animal evolution. This creature, called Westlothiana lizziae, is one of the […] Written by Admin June 6, 2025June 6, 2025 Saving Bookmark this article Bookmarked
Life Sciences Two plant species invent the same chemically complex and medically interesting substance The elucidation of the biosynthetic pathway of ipecacuanha alkaloids shows how two distantly related plant species could develop the same substance independently. Plants produce an enormous abundance of natural products. Many plant natural products are ancestry-specific and occur only in certain plant families, sometimes only in a single species. Interestingly, however, the same substances can […] Written by Admin June 5, 2025June 5, 2025 Saving Bookmark this article Bookmarked
Life Sciences DNA floating in the air tracks wildlife, viruses — even drugs Dublin is known as a city where you can enjoy a few pints of Guiness, get a warm welcome from the locals and hear lively traditional music drifting out of pubs and into the city air. But it’s not just music floating on the breeze. The air of Dublin also contains cannabis, poppy, even magic […] Written by Admin June 4, 2025June 4, 2025 Saving Bookmark this article Bookmarked
Life Sciences Eating an array of smaller fish could be nutrient-dense solution to overfishing To satisfy the seafood needs of billions of people, offering them access to a more biodiverse array of fish creates opportunities to mix-and-match species to obtain better nutrition from smaller portions of fish. The right combination of certain species can provide up to 60% more nutrients than if someone ate the same quantity of even […] Written by Admin June 3, 2025June 3, 2025 Saving Bookmark this article Bookmarked
Life Sciences Student discovers long-awaited mystery fungus sought by LSD’s inventor Making a discovery with the potential for innovative applications in pharmaceutical development, a West Virginia University microbiology student has found a long sought-after fungus that produces effects similar to the semisynthetic drug LSD, which is used to treat conditions like depression, post-traumatic stress disorder and addiction. Corinne Hazel, of Delaware, Ohio, an environmental microbiology major […] Written by Admin June 2, 2025June 2, 2025 Saving Bookmark this article Bookmarked
Mammals didn’t walk upright until late—here’s what fossils reveal For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […] Written by Admin June 30, 2025June 30, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Mammals didn’t walk upright until late—here’s what fossils reveal For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […] Written by Admin June 30, 2025June 30, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked