Life Sciences Unlocking the secrets of bat immunity Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease outcomes these viruses cause in humans, bats generally do not show obvious signs of viral illness following infection. An international research team […] Written by Admin May 21, 2025May 21, 2025 Saving Bookmark this article Bookmarked
Life Sciences Common diabetes drug helps chickens lay more eggs What do chickens and people with a common reproductive disorder have in common? More than one might think — and a widely-used diabetes medication might just be the surprising link. At Penn State, researchers discovered that metformin, a drug usually prescribed for type 2 diabetes and polycystic ovary syndrome (PCOS) in humans, can actually help […] Written by Admin May 20, 2025May 20, 2025 Saving Bookmark this article Bookmarked
Life Sciences Could nanoplastics in the environment turn E. coli into a bigger villain? Nanoplastics are everywhere. These fragments are so tiny they can accumulate on bacteria and be taken up by plant roots; they’re in our food, our water, and our bodies. Scientists don’t know the full extent of their impacts on our health, but new research from University of Illinois Urbana-Champaign food scientists suggests certain nanoplastics may […] Written by Admin May 19, 2025May 19, 2025 Saving Bookmark this article Bookmarked
Life Sciences Novel molecular maneuver helps malaria parasite dodge the immune system Researchers at Weill Cornell Medicine have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system, sometimes for years. It turns out that the parasite, Plasmodium falciparum, can shut down a key set of genes, rendering itself “immunologically invisible.” “This finding provides another piece of […] Written by Admin May 18, 2025May 18, 2025 Saving Bookmark this article Bookmarked
Life Sciences How antibiotic resistance to fusidic acid works In a new article published in Nature Communications, researchers from Uppsala Antibiotic Center, Uppsala University and SciLifeLab describe a fundamental mechanism of antibiotic resistance. What happens in a bacterium that is resistant to the antibiotic fusidic acid? With a stop-motion movie at the atomic level, they can show that the resistance protein FusB works nearly […] Written by Admin May 17, 2025May 17, 2025 Saving Bookmark this article Bookmarked
Life Sciences In healthy aging, carb quality counts Intakes of dietary fiber, high-quality and total carbohydrates in midlife were favorably linked to healthy aging and other positive health outcomes in older women, according to a new study by researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University and Harvard T.H. Chan School of Public Health. The […] Written by Admin May 16, 2025May 16, 2025 Saving Bookmark this article Bookmarked
Life Sciences World’s largest bat organoid platform paves the way for pandemic preparedness Did you know that more than 75% of new infectious diseases affecting humans originally come from animals? Bats, in particular, are natural hosts to some of the world’s most dangerous viruses, including those responsible for COVID-19 (SARS-CoV-2), MERS-CoV, influenza A, and hantavirus outbreaks. Yet, despite their importance, scientists have long struggled to study how these […] Written by Admin May 15, 2025May 15, 2025 Saving Bookmark this article Bookmarked
Life Sciences Genome of near-extinct northern white rhino offers hope for reviving the species The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, an international team of scientists at Scripps Research, the San Diego Zoo Wildlife Alliance, Max Planck Institute for Molecular Genetics, and other collaborators have mapped the entire genome […] Written by Admin May 14, 2025May 14, 2025 Saving Bookmark this article Bookmarked
Life Sciences A plant you’ve never heard of can do what scientists once thought impossible About 3.7 billion years ago, a string of naturally occurring amino — the same kind that astronomers have found in meteorites and just recently in a stellar nursery near the center of the Milky Way Galaxy — reacted with a naturally occurring catalyst and began the fateful process of self-assembled replication. One of the most […] Written by Admin May 13, 2025May 13, 2025 Saving Bookmark this article Bookmarked
Life Sciences From prehistoric resident to runaway pet: First tegu fossil found in the U.S. Originally from South America, the charismatic tegu made its way to the United States via the pet trade of the 1990s. After wreaking havoc in Florida’s ecosystems, the exotic lizard was classified as an invasive species. But a recent discovery from the Florida Museum of Natural History reveals the reptiles are no strangers to the […] Written by Admin May 12, 2025May 12, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked