Life Sciences Researchers map 7,000-year-old genetic mutation that protects against HIV Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose — and how it protected our ancestors from ancient diseases. What do a millennia-old human from the Black Sea region and modern HIV medicine have in common? Quite a lot, it turns out, according to […] Written by Admin May 11, 2025May 11, 2025 Saving Bookmark this article Bookmarked
Life Sciences The origins of language | ScienceDaily Chimpanzees are capable of complex communication: The human capacity for language may not be as unique as previously thought. Chimpanzees have a complex communication system that allows them to combine calls to create new meanings, similar to human language. Combining calls creatively: Chimpanzees use four ways to change meaning when combining single calls into two-call […] Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Life Sciences First fossil evidence of endangered tropical tree discovered For the first time, scientists have discovered fossil evidence of an endangered, living tropical tree species. The unprecedented find was made in Brunei, a country on the large island of Borneo, and reveals a critical piece of the ancient history of Asia’s rainforests, highlighting the urgent need for conservation in the region, according to researchers […] Written by Admin May 9, 2025May 9, 2025 Saving Bookmark this article Bookmarked
Life Sciences AI-designed DNA controls genes in healthy mammalian cells for first time A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. Researchers at the Centre for Genomic Regulation (CRG) created an AI tool which dreams up DNA regulatory sequences not seen before in nature. The model can […] Written by Admin May 8, 2025May 8, 2025 Saving Bookmark this article Bookmarked
Life Sciences Triassic fossil reveals nature’s best jaw for hunting fast fish The best jaw for hunting fast fish is long and full of sharp teeth. This makes sense to us, but it also makes sense in nature: New fossil evidence from Virginia Tech geoscientists revealed that different species of predatory fish independently evolved similar jaw structure hundreds of millions of years apart. “The same evolutionary problem […] Written by Admin May 7, 2025May 7, 2025 Saving Bookmark this article Bookmarked
Life Sciences Two new crocodile species discovered McGill University researchers, in collaboration with Mexican scientists, have discovered two previously unknown species of crocodiles, one living on the island of Cozumel and the other on the atoll of Banco Chinchorro, both off the Yucatán Peninsula. The findings challenge long-held assumptions about the American crocodile (Crocodylus acutus) and highlight the urgent need for conservation […] Written by Admin May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Life Sciences Saving the Asian ‘unicorn’ — if it still exists Is it extinct, or does it still roam somewhere deep in the misty highland forests of Vietnam and Laos? It has been nicknamed the Asian unicorn due to its almost mythical rarity, and it is the most recently discovered large land mammal, becoming known to science as late as in 1992. Even then, it was […] Written by Admin May 5, 2025May 5, 2025 Saving Bookmark this article Bookmarked
Life Sciences Traditional forest medicinal plant ghost pipe used differently today Despite a long history of traditional medicinal use in the United States, the collection, consumption and efficacy of the peculiar forest plant aptly named ghost pipe, scientific name Monotropa uniflora, remains a mystery. Now, with social media and the internet driving a resurgence in the harvest and economic trade of the parasitic species — which […] Written by Admin May 4, 2025May 4, 2025 Saving Bookmark this article Bookmarked
Life Sciences Evaluation of Biofilm Forming Potential and Antimicrobial… Pseudomonas aeruginosa and Staphylococcus aureus are prominent pathogens responsible for device-associated infections that pose a significant challenge in clinical management. The biofilm-forming ability of these bacteria is a major factor contributing to treatment failures and the recurrence of infections. This study was conducted to evaluate the biofilm production potential of these bacteria isolated from urinary […] Written by Hoceini, Amina May 3, 2025May 3, 2025 Saving Bookmark this article Bookmarked
Life Sciences Why did some ancient animals fossilize while others vanished? Why do some ancient animals become fossils while others disappear without a trace? A new study from the University of Lausanne, published in Nature Communications, reveals that part of the answer lies in the body itself. The research shows that an animal’s size and chemical makeup can play an important role in determining whether it’s […] Written by Admin May 2, 2025May 2, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked