Pharmaceuticals and Drug Development

  1. Pharmaceuticals and Drug Development

Young Vilnius University Scientist I. Mogila Received Birnstiel Award for Breakthrough in CRISPR-Cas10 Research

“I feel great. The award recognises the CRISPR-Cas10 research I conducted during my PhD studies, investigating the bacterial defence system against viruses. I would like to thank my PhD supervisor, Dr Gintautas Tamulaitis, and the Head of the VU LSC School of Doctoral Studies, Dr Daiva Baltriukiene, for their encouragement and for nominating me for […]
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  1. Pharmaceuticals and Drug Development

Applied Therapeutics Receives Complete Response Letter from U.S. FDA Regarding New Drug Application for Govorestat for Classic Galactosemia

NEW YORK, Nov. 27, 2024 (GLOBE NEWSWIRE) — Applied Therapeutics, Inc. (Nasdaq: APLT), a biopharmaceutical company dedicated to creating transformative treatments for rare disease, today announced that the U.S. Food and Drug Administration (FDA) has…
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  1. Pharmaceuticals and Drug Development

VU Researchers Publish Study on the Mechanism of CRISPR-Cas “Protein Scissors” in Molecular Cell

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, also known as DNA or gene ‘scissors’, which have revolutionized the field of genome editing, enabling scientists to […]
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  1. Pharmaceuticals and Drug Development

Pioneer Group’s life sciences campuses host biggest Ada Lovelace Day event to date

The event was the seventh annual Ada Lovelace Day celebration run by Pioneer in collaboration with educational charity Ignite! and the biggest to date. The two-day event showcased the real-world impact of women in science through interactive workshops held at MediCity Nottingham, Kent Science Park, Wilton Centre, Hexagon Tower, BioCity Glasgow, BioCity Nottingham, Edinburgh Technopole, […]
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Scientists uncover new way viruses fight back against bacteria

Is fake meat good to eat? Processed plant-based meat alternatives linked to depression risk in vegetarians

There is mounting evidence suggesting that ultra processed foods (UPF) are bad for our health; but if you stick to a vegetarian diet, is that still the case? Plant-Based Meat Alternatives (PBMA) are considered to be ultra-processed foods and may be associated with similar harms. In the first study of its kind, published in Food […]
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Worlwide

Scientists uncover new way viruses fight back against bacteria

Is fake meat good to eat? Processed plant-based meat alternatives linked to depression risk in vegetarians

There is mounting evidence suggesting that ultra processed foods (UPF) are bad for our health; but if you stick to a vegetarian diet, is that still the case? Plant-Based Meat Alternatives (PBMA) are considered to be ultra-processed foods and may be associated with similar harms. In the first study of its kind, published in Food […]
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SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) exhibit differences in their inflammatory responses and pulmonary damage, yet the specific mechanisms remain unclear. Here, we discovered that the SARS-CoV-2 nucleocapsid (N) protein inhibits the activation of the nuclear factor-κB (NF-κB) pathway and downstream signal transduction by impeding the assembly […]
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