Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.db0ed217.1759485526.140831a2 Written by Admin October 3, 2025October 3, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development BRIM closes a $45.8 million rights issue early to accelerate its pipeline of regenerative peptides The fund will be used to accelerate the development of several assets within BRIM’s pipeline, including the ongoing phase 3 trial of lead asset BRM421 for dry eye disease (DED) in the US and the enrollment of the phase 2 trial of BRM424 for neurotrophic keratitis (NK). BRIM will also progress the development of BRM521 […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom September 27, 2025September 27, 2025 Saving Bookmark this article Bookmarked
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Pharmaceuticals and Drug Development Stealth Biotherapeutics Announces FDA Acceptance of Elamipretide NDA Resubmission NEEDHAM, Mass., Aug. 21, 2025 /PRNewswire/ — Stealth BioTherapeutics, a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel therapies for diseases involving mitochondrial dysfunction… Written by Admin September 15, 2025September 15, 2025 Saving Bookmark this article Bookmarked
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Pharmaceuticals and Drug Development ELRIG UK Establishes Engagement Strategy Work Group Cambridge, UK, 14 September 2023: The European Laboratory Research & Innovation Group (ELRIG) UK today announced the formation of its Engagement Strategy Work Group (ESWG). The group will provide strategic direction and guidance to help ensure the ELRIG community continues to grow and thrive. It aims to engage audiences in different ways, beyond face-to-face events, […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom September 3, 2025September 3, 2025 Saving Bookmark this article Bookmarked
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Pharmaceuticals and Drug Development PTC Therapeutics Receives Complete Response Letter for Vatiquinone NDA WARREN, N.J., Aug. 19, 2025 /PRNewswire/ — PTC Therapeutics, Inc. (NASDAQ: PTCT) announced today that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) related to the New Drug Application (NDA) for vatiquinone… Written by Admin August 22, 2025August 22, 2025 Saving Bookmark this article Bookmarked
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Pharmaceuticals and Drug Development New £30m Initiative to Address Global Threat by Accelerating the Pace of Antimicrobial Innovation Innovate UK, LifeArc, and Medicines Discovery Catapult (MDC) have joined forces to create PACE (Pathways to Antimicrobial Clinical Efficacy), a £30 million initiative supporting early-stage innovation against antimicrobial resistance (AMR) to save lives. PACE has today (19 October 2023) announced its first funding call with up to £10 million available to support innovators developing new […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom August 10, 2025August 10, 2025 Saving Bookmark this article Bookmarked
High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
The hidden harm from salmon farming In addition to parasites, pathogens, chemical residues, and other treatments can persist in cages. Fallow sites are expected to undergo complete removal of fish and nets to limit pathogen carryover. Campaigners, however, say the Aird site “continued functioning as a reservoir of disease and flesh-eating lice.” Read: The catch. Unsustainable Abigail Penny, executive director of […] Written by brendan December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
The hidden harm from salmon farming In addition to parasites, pathogens, chemical residues, and other treatments can persist in cages. Fallow sites are expected to undergo complete removal of fish and nets to limit pathogen carryover. Campaigners, however, say the Aird site “continued functioning as a reservoir of disease and flesh-eating lice.” Read: The catch. Unsustainable Abigail Penny, executive director of […] Written by brendan December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Doomed ants send a final scent to save their colony Ant societies behave like tightly integrated “superorganisms,” where thousands of individuals work together in a way that resembles the coordinated activity of cells in a body. Researchers at the Institute of Science and Technology Austria (ISTA) have found that terminally ill ant brood release a distinctive odor, similar to the way infected body cells send […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked