Pharmaceuticals and Drug Development

  1. Pharmaceuticals and Drug Development

Applied Therapeutics Receives Complete Response Letter from U.S. FDA Regarding New Drug Application for Govorestat for Classic Galactosemia

NEW YORK, Nov. 27, 2024 (GLOBE NEWSWIRE) — Applied Therapeutics, Inc. (Nasdaq: APLT), a biopharmaceutical company dedicated to creating transformative treatments for rare disease, today announced that the U.S. Food and Drug Administration (FDA) has…
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  1. Pharmaceuticals and Drug Development

VU Researchers Publish Study on the Mechanism of CRISPR-Cas “Protein Scissors” in Molecular Cell

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, also known as DNA or gene ‘scissors’, which have revolutionized the field of genome editing, enabling scientists to […]
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  1. Pharmaceuticals and Drug Development

Pioneer Group’s life sciences campuses host biggest Ada Lovelace Day event to date

The event was the seventh annual Ada Lovelace Day celebration run by Pioneer in collaboration with educational charity Ignite! and the biggest to date. The two-day event showcased the real-world impact of women in science through interactive workshops held at MediCity Nottingham, Kent Science Park, Wilton Centre, Hexagon Tower, BioCity Glasgow, BioCity Nottingham, Edinburgh Technopole, […]
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  1. Pharmaceuticals and Drug Development

Stealth BioTherapeutics Announces Positive Vote from FDA Advisory Committee Meeting Supporting Potential Approval of Elamipretide for the Treatment of Barth Syndrome

NEEDHAM, Mass., Oct. 11, 2024 /PRNewswire/ — Stealth BioTherapeutics Inc. (the “Company” or “Stealth”), a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel…
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  1. Pharmaceuticals and Drug Development

KalVista Announces FDA Acceptance of New Drug Application for Sebetralstat for Oral On-Demand Treatment of Hereditary Angioedema

CAMBRIDGE, Mass. & SALISBURY, England–(BUSINESS WIRE)–Sep. 3, 2024– KalVista Pharmaceuticals, Inc. (NASDAQ: KALV), today announced that the U.S. Food and Drug Administration (FDA) has accepted its New Drug Application (NDA) for sebetralstat…
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How AI is supercharging plant immunity to fight deadly bacteria

How AI is supercharging plant immunity to fight deadly bacteria

Scientists at the University of California, Davis, used artificial intelligence to help plants recognize a wider range of bacterial threats — which may lead to new ways to protect crops like tomatoes and potatoes from devastating diseases. The study was published in Nature Plants. Plants, like animals, have immune systems. Part of their defense toolkit […]
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Koalas on the brink: Precision DNA test offers a lifeline to Australia’s icons

Koalas on the brink: Precision DNA test offers a lifeline to Australia’s icons

A University of Queensland-led project has developed a tool to standardize genetic testing of koala populations, providing a significant boost to conservation and recovery efforts. Dr Lyndal Hulse from UQ’s School of the Environment said the standardized koala genetic marker panel provides a consistent method for researchers nationwide to capture and share koala genetic variation, […]
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How AI is supercharging plant immunity to fight deadly bacteria

How AI is supercharging plant immunity to fight deadly bacteria

Scientists at the University of California, Davis, used artificial intelligence to help plants recognize a wider range of bacterial threats — which may lead to new ways to protect crops like tomatoes and potatoes from devastating diseases. The study was published in Nature Plants. Plants, like animals, have immune systems. Part of their defense toolkit […]
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Koalas on the brink: Precision DNA test offers a lifeline to Australia’s icons

Koalas on the brink: Precision DNA test offers a lifeline to Australia’s icons

A University of Queensland-led project has developed a tool to standardize genetic testing of koala populations, providing a significant boost to conservation and recovery efforts. Dr Lyndal Hulse from UQ’s School of the Environment said the standardized koala genetic marker panel provides a consistent method for researchers nationwide to capture and share koala genetic variation, […]
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AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact

Membrane contact sites (MCSs) establish organelle interactomes in cells to enable communication and exchange of materials. Volume EM (vEM) is ideally suited for MCS analyses, but semantic segmentation of large vEM datasets remains challenging. Recent adoption of artificial intelligence (AI) for segmentation has greatly enhanced our analysis capabilities. However, we show that organelle boundaries, which […]
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