Life Sciences Study explores how traumatic brain injury (TBI) may be linked to Alzheimer’s disease Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk for developing Alzheimer’s disease later in life. Researchers led by The Ohio State University Wexner Medical Center and College of Medicine used mouse models and human post-mortem brain tissue to study the molecular underpinnings that may increase the […] Written by Admin October 17, 2024October 17, 2024 Saving Bookmark this article Bookmarked
Life Sciences Researchers are closing in on a mouse model for late-onset Alzheimer’s Mice don’t get Alzheimer’s — and while that’s good news for mice, it’s a big problem for biomedical researchers seeking to understand the disease and test new treatments. Now, researchers at The Jackson Laboratory are working to create the first strain of mice that’s genetically susceptible to late-onset Alzheimer’s, with potentially transformative implications for dementia […] Written by Admin July 25, 2024July 25, 2024 Saving Bookmark this article Bookmarked
Life Sciences Scientists discover links between Alzheimer’s disease and gut microbiota Researchers have discovered the link between the gut microbiota and Alzheimer’s disease. For the first time, researchers have found that Alzheimer’s symptoms can be transferred to a healthy young organism via the gut microbiota, confirming its role in the disease. The research was led by Professor Yvonne Nolan, APC Microbiome Ireland, a world leading SFI […] Written by Admin October 19, 2023October 19, 2023 Saving Bookmark this article Bookmarked
MYO18B promotes lysosomal exocytosis by facilitating focal adhesion maturation Many cancer cells exhibit increased amounts of paucimannose glycans, which are truncated N-glycan structures rarely found in mammals. Paucimannosidic proteins are proposedly generated within lysosomes and exposed on the cell surface through a yet uncertain mechanism. In this study, we revealed that paucimannosidic proteins are produced by lysosomal glycosidases and secreted via lysosomal exocytosis. Interestingly, […] Written by Admin January 6, 2025January 6, 2025 Saving Bookmark this article Bookmarked
Climate School Expands Faculty – State of the Planet The Columbia Climate School’s faculty will expand beginning on January 1, 2025. “With the addition of these new faculty, along with the incoming Climate School dean Alexis Abramson, who will be a professor of climate, the school’s faculty will increase to 29 in the new year,” said interim dean Jeffrey Shaman. The following faculty will join the Climate School […] Written by Columbia Climate School January 6, 2025January 6, 2025 Saving Bookmark this article Bookmarked
MYO18B promotes lysosomal exocytosis by facilitating focal adhesion maturation Many cancer cells exhibit increased amounts of paucimannose glycans, which are truncated N-glycan structures rarely found in mammals. Paucimannosidic proteins are proposedly generated within lysosomes and exposed on the cell surface through a yet uncertain mechanism. In this study, we revealed that paucimannosidic proteins are produced by lysosomal glycosidases and secreted via lysosomal exocytosis. Interestingly, […] Written by Admin January 6, 2025January 6, 2025 Saving Bookmark this article Bookmarked
Climate School Expands Faculty – State of the Planet The Columbia Climate School’s faculty will expand beginning on January 1, 2025. “With the addition of these new faculty, along with the incoming Climate School dean Alexis Abramson, who will be a professor of climate, the school’s faculty will increase to 29 in the new year,” said interim dean Jeffrey Shaman. The following faculty will join the Climate School […] Written by Columbia Climate School January 6, 2025January 6, 2025 Saving Bookmark this article Bookmarked
Pollinators, pollen and varieties determine fruit quality Pollination by animals contributes to a third of global food production, but little research has been done into the extent to which the identity of pollinators, pollen and crop varieties influence fruit quality when it comes to the nutritional, sensory and commercial value of crops. Pollinators influence the quality of crops through their movement patterns […] Written by Admin January 6, 2025January 6, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked