Life Sciences Study explores how traumatic brain injury (TBI) may be linked to Alzheimer’s disease Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk for developing Alzheimer’s disease later in life. Researchers led by The Ohio State University Wexner Medical Center and College of Medicine used mouse models and human post-mortem brain tissue to study the molecular underpinnings that may increase the […] Written by Admin October 17, 2024October 17, 2024 Saving Bookmark this article Bookmarked
Life Sciences Researchers are closing in on a mouse model for late-onset Alzheimer’s Mice don’t get Alzheimer’s — and while that’s good news for mice, it’s a big problem for biomedical researchers seeking to understand the disease and test new treatments. Now, researchers at The Jackson Laboratory are working to create the first strain of mice that’s genetically susceptible to late-onset Alzheimer’s, with potentially transformative implications for dementia […] Written by Admin July 25, 2024July 25, 2024 Saving Bookmark this article Bookmarked
Life Sciences Scientists discover links between Alzheimer’s disease and gut microbiota Researchers have discovered the link between the gut microbiota and Alzheimer’s disease. For the first time, researchers have found that Alzheimer’s symptoms can be transferred to a healthy young organism via the gut microbiota, confirming its role in the disease. The research was led by Professor Yvonne Nolan, APC Microbiome Ireland, a world leading SFI […] Written by Admin October 19, 2023October 19, 2023 Saving Bookmark this article Bookmarked
Scientists recreate mouse from gene older than animal life Published in Nature Communications, an international team of researchers has achieved an unprecedented milestone: the creation of mouse stem cells capable of generating a fully developed mouse using genetic tools from a unicellular organism, with which we share a common ancestor that predates animals. This breakthrough reshapes our understanding of the genetic origins of stem […] Written by Admin November 19, 2024November 19, 2024 Saving Bookmark this article Bookmarked
VU Researchers Publish Study on the Mechanism of CRISPR-Cas “Protein Scissors” in Molecular Cell CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, also known as DNA or gene ‘scissors’, which have revolutionized the field of genome editing, enabling scientists to […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom November 19, 2024November 19, 2024 Saving Bookmark this article Bookmarked
Scientists recreate mouse from gene older than animal life Published in Nature Communications, an international team of researchers has achieved an unprecedented milestone: the creation of mouse stem cells capable of generating a fully developed mouse using genetic tools from a unicellular organism, with which we share a common ancestor that predates animals. This breakthrough reshapes our understanding of the genetic origins of stem […] Written by Admin November 19, 2024November 19, 2024 Saving Bookmark this article Bookmarked
VU Researchers Publish Study on the Mechanism of CRISPR-Cas “Protein Scissors” in Molecular Cell CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, also known as DNA or gene ‘scissors’, which have revolutionized the field of genome editing, enabling scientists to […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom November 19, 2024November 19, 2024 Saving Bookmark this article Bookmarked
Visualizing ER-phagy and ER architecture in vivo ER-phagy is an evolutionarily conserved mechanism crucial for maintaining cellular homeostasis. However, significant gaps persist in our understanding of how ER-phagy and the ER network vary across cell subtypes, tissues, and organs. Furthermore, the pathophysiological relevance of ER-phagy remains poorly elucidated. Addressing these questions requires developing quantifiable methods to visualize ER-phagy and ER architecture in […] Written by Admin November 19, 2024November 19, 2024 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked