Life Sciences Hijacking the command center of the cell: Nuclear parasites in deep-sea mussels Most animals live in intimate relationships with bacteria. Some of these bacteria live inside the cells of their hosts, but only very few are able to live inside cell organelles (structures inside the cell, like organs in the body). One group of bacteria have figured out how to colonize the nuclei of their hosts, a […] Written by Admin September 7, 2024September 7, 2024 Saving Bookmark this article Bookmarked
A silent ocean pandemic is wiping out sea urchins worldwide Sea urchins play a crucial role in the ocean, acting as ecosystem engineers much like large grazers on land. As they feed on seaweed and seagrass, they trim back algae and help protect slow-growing species such as corals and certain calcifying algae. In turn, sea urchins are an important food source for many marine mammals, […] Written by Admin January 6, 2026January 6, 2026 Saving Bookmark this article Bookmarked
The traffic controller: GARLH4 dictates neuroligin synapse-type preference Neuroligin isoforms are commonly thought to intrinsically specify synapse identity. In this issue, Yamasaki et al. (https://doi.org/10.1083/jcb.202507190) show that the auxiliary protein GARLH4 (LHFPL4) instead dictates neuroligin preference via competitive hierarchy, enabling dynamic reassignment between excitatory and inhibitory postsynaptic domains. Written by Admin January 5, 2026January 5, 2026 Saving Bookmark this article Bookmarked
A silent ocean pandemic is wiping out sea urchins worldwide Sea urchins play a crucial role in the ocean, acting as ecosystem engineers much like large grazers on land. As they feed on seaweed and seagrass, they trim back algae and help protect slow-growing species such as corals and certain calcifying algae. In turn, sea urchins are an important food source for many marine mammals, […] Written by Admin January 6, 2026January 6, 2026 Saving Bookmark this article Bookmarked
The traffic controller: GARLH4 dictates neuroligin synapse-type preference Neuroligin isoforms are commonly thought to intrinsically specify synapse identity. In this issue, Yamasaki et al. (https://doi.org/10.1083/jcb.202507190) show that the auxiliary protein GARLH4 (LHFPL4) instead dictates neuroligin preference via competitive hierarchy, enabling dynamic reassignment between excitatory and inhibitory postsynaptic domains. Written by Admin January 5, 2026January 5, 2026 Saving Bookmark this article Bookmarked
Kshamenk has died Kshamenk, the last captive orca in Argentina, has died. His death has been attributed by Mundo Marino to cardiorespiratory arrest, with reference to age-related decline. With it, the possibility of any future intervention—relocation, rehabilitation, sanctuary—has closed. READ: His name is Kshamenk What remains is not a question about how he died, but about how he lived, […] Written by brendan January 5, 2026January 5, 2026 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked
