Life Sciences Protein labeling of tens of millions of densely packed cells in organ-scale tissues A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility. Using the technology, the team was able to richly label whole rodent brains and other large tissue samples in a single day. In their new study in Nature […] Written by Admin January 26, 2025January 26, 2025 Saving Bookmark this article Bookmarked
The origins of language | ScienceDaily Chimpanzees are capable of complex communication: The human capacity for language may not be as unique as previously thought. Chimpanzees have a complex communication system that allows them to combine calls to create new meanings, similar to human language. Combining calls creatively: Chimpanzees use four ways to change meaning when combining single calls into two-call […] Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia In this issue, Jaffray and colleagues (https://doi.org/10.1083/jcb.202407133) detail the molecular machinery required to degrade the oncogene PML in response to arsenic treatment. Different posttranslational modifiers team up: ubiquitin, SUMO1, and -2/3, linked by the SUMO-targeted ubiquitin ligases TOPORS and RNF4. Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
The origins of language | ScienceDaily Chimpanzees are capable of complex communication: The human capacity for language may not be as unique as previously thought. Chimpanzees have a complex communication system that allows them to combine calls to create new meanings, similar to human language. Combining calls creatively: Chimpanzees use four ways to change meaning when combining single calls into two-call […] Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia In this issue, Jaffray and colleagues (https://doi.org/10.1083/jcb.202407133) detail the molecular machinery required to degrade the oncogene PML in response to arsenic treatment. Different posttranslational modifiers team up: ubiquitin, SUMO1, and -2/3, linked by the SUMO-targeted ubiquitin ligases TOPORS and RNF4. Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Chimps go wild on boozy fruit Wild chimpanzees have been pictured eating and sharing fruit containing alcohol for the first time. Researchers set up cameras in Guinea-Bissau’s Cantanhez National Park and recorded footage of chimps sharing fermented African breadfruit. The scientists said the findings raised questions about whether and why chimps deliberately seek out alcohol. Ethanolic And they likened it to […] Written by brendan May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked
