Life Sciences Programming cells: Revolutionizing genetic circuits with cutting-edge RNA tools Professor Jongmin Kim’s research team at POSTECH developed a new technology that improves the precision and integration density of synthetic genetic circuits. The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the ‘Synthetic Translational Coupling Element […] Written by Admin December 23, 2024December 23, 2024 Saving Bookmark this article Bookmarked
FDA Issues Draft Guidance Q&A on Developing Potential Cellular and Gene Therapy Products – Duane Morris Life Sciences Law In November 2024, the U.S. Food and Drug Administration (FDA) issued draft Guidance responding to frequently asked questions about developing cellular and gene therapy (CGT) products. This draft Guidance supplements existing finalized and draft Guidance on CGT products. Read the full Alert on the Duane Morris LLP Website. Written by Duane Morris January 28, 2025January 28, 2025 Saving Bookmark this article Bookmarked
FAM43A coordinates mtDNA replication and mitochondrial biogenesis in response to mtDNA depletion Mitochondrial retrograde signaling (MRS) pathways relay the functional status of mitochondria to elicit homeostatic or adaptive changes in nuclear gene expression. Budding yeast have “intergenomic signaling” pathways that sense the amount of mitochondrial DNA (mtDNA) independently of oxidative phosphorylation (OXPHOS), the primary function of genes encoded by mtDNA. However, MRS pathways that sense the amount […] Written by Admin January 28, 2025January 28, 2025 Saving Bookmark this article Bookmarked
FDA Issues Draft Guidance Q&A on Developing Potential Cellular and Gene Therapy Products – Duane Morris Life Sciences Law In November 2024, the U.S. Food and Drug Administration (FDA) issued draft Guidance responding to frequently asked questions about developing cellular and gene therapy (CGT) products. This draft Guidance supplements existing finalized and draft Guidance on CGT products. Read the full Alert on the Duane Morris LLP Website. Written by Duane Morris January 28, 2025January 28, 2025 Saving Bookmark this article Bookmarked
FAM43A coordinates mtDNA replication and mitochondrial biogenesis in response to mtDNA depletion Mitochondrial retrograde signaling (MRS) pathways relay the functional status of mitochondria to elicit homeostatic or adaptive changes in nuclear gene expression. Budding yeast have “intergenomic signaling” pathways that sense the amount of mitochondrial DNA (mtDNA) independently of oxidative phosphorylation (OXPHOS), the primary function of genes encoded by mtDNA. However, MRS pathways that sense the amount […] Written by Admin January 28, 2025January 28, 2025 Saving Bookmark this article Bookmarked
Honoring Iceland’s Changing Glacial Landscape – State of the Planet In May 2023, artists Jim Schantz and Peter Bremers traveled to Iceland’s Vatnajökull— the second largest glacier in Europe. Witnessing the colossal ice formations up-close, as well as the markers of climate change they carry, inspired the two artists to collaborate on “Homage to the Glacier,” a recent exhibition at the Berkshire Museum in Pittsfield, […] Written by Guest January 28, 2025January 28, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked