Life Sciences In silico Structural and Functional Characterization of an… Actinoalloteichus hoggarensis is a rare bacterial species that was isolated from the Algerian Saharan desert and is known for producing biologically active compounds. Despite its potential, little is understood about the enzymes it produces, including endoglucanases. These cellulase enzymes break down cellulose, the primary structural component of plant cell walls that provides strength and rigidity. […] Written by Bakli, Mahfoud April 21, 2025April 21, 2025 Saving Bookmark this article Bookmarked
Researchers map 7,000-year-old genetic mutation that protects against HIV Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose — and how it protected our ancestors from ancient diseases. What do a millennia-old human from the Black Sea region and modern HIV medicine have in common? Quite a lot, it turns out, according to […] Written by Admin May 11, 2025May 11, 2025 Saving Bookmark this article Bookmarked
The origins of language | ScienceDaily Chimpanzees are capable of complex communication: The human capacity for language may not be as unique as previously thought. Chimpanzees have a complex communication system that allows them to combine calls to create new meanings, similar to human language. Combining calls creatively: Chimpanzees use four ways to change meaning when combining single calls into two-call […] Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Researchers map 7,000-year-old genetic mutation that protects against HIV Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose — and how it protected our ancestors from ancient diseases. What do a millennia-old human from the Black Sea region and modern HIV medicine have in common? Quite a lot, it turns out, according to […] Written by Admin May 11, 2025May 11, 2025 Saving Bookmark this article Bookmarked
The origins of language | ScienceDaily Chimpanzees are capable of complex communication: The human capacity for language may not be as unique as previously thought. Chimpanzees have a complex communication system that allows them to combine calls to create new meanings, similar to human language. Combining calls creatively: Chimpanzees use four ways to change meaning when combining single calls into two-call […] Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia In this issue, Jaffray and colleagues (https://doi.org/10.1083/jcb.202407133) detail the molecular machinery required to degrade the oncogene PML in response to arsenic treatment. Different posttranslational modifiers team up: ubiquitin, SUMO1, and -2/3, linked by the SUMO-targeted ubiquitin ligases TOPORS and RNF4. Written by Admin May 10, 2025May 10, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked