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BioNtech reports Car-T/mRNA booster study results at ESMO
  1. Biotechnology

BioNtech reports Car-T/mRNA booster study results at ESMO

BioNtech SE has reported preliminary Phase I/II results with BNT211-01 (NEO-PTC-01) and CarVAC at ESMO conference in Madrid Testing different dose levels of its adoptive cell therapy BNT.221-01, a combination of Claudin 6 (CLDN6)-targeted Car-T cells (derived from NEO-PTC-01, initially developed by tody’s BioNTech subsidiary Neon Therapeutics) and the mRNA-based Car-T  booster CarVac (CAR-T cell […]
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Antiverse and GlobalBio Inc. extend collaboration
  1. Biotechnology

Antiverse and GlobalBio Inc. extend collaboration

Antiverse Ltd and GlobalBio Inc. have extend their cancer antibody partnership to progress two PD-1 modulators to preclinial development AI specialist Antiverse Ltd (Cardiff, UK) and antobody engeeniering expert GlobalBio, Inc. (New York, USA) will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy. The initial collaboration successfully resulted in the generation […]
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SpliceBio has made up a US $216m alliance with Spark Therapeutics
  1. Biotechnology

SpliceBio has made up a US $216m alliance with Spark Therapeutics

SpliceBio has licenced its intein technlogy to Roche’s gene therapy subsidiary Spark Therapeutics to develop a gene therapy targeting an undisclosed inherited retinal disease. Under a globally exclusive licence option agreement with Roche AG, SpliceBio secures an upfront payment, opt-in and milestone payments up to $216m plus royalties in exchange to its recombinant split […]
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Scientists uncover new way viruses fight back against bacteria

Microbes in mouth reflect lifestyle choices

Lifestyle can shape the composition of beneficial bacteria and other microorganisms within the mouth, according to a new study led by Penn State biologists. The international team revealed how the “oral microbiome” differs over a range of subsistence strategies — from nomadic hunter gatherers to farmers to industrialized groups — and found that lifestyle, as […]
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Scientists uncover new way viruses fight back against bacteria

Fossil of huge terror bird offers new information about wildlife in South America 12 million years ago

Researchers including a Johns Hopkins University evolutionary biologist report they have analyzed a fossil of an extinct giant meat-eating bird — which they say could be the largest known member of its kind — providing new information about animal life in northern South America millions of years ago. The evidence lies in the leg bone […]
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Worlwide

Scientists uncover new way viruses fight back against bacteria

Microbes in mouth reflect lifestyle choices

Lifestyle can shape the composition of beneficial bacteria and other microorganisms within the mouth, according to a new study led by Penn State biologists. The international team revealed how the “oral microbiome” differs over a range of subsistence strategies — from nomadic hunter gatherers to farmers to industrialized groups — and found that lifestyle, as […]
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Scientists uncover new way viruses fight back against bacteria

Fossil of huge terror bird offers new information about wildlife in South America 12 million years ago

Researchers including a Johns Hopkins University evolutionary biologist report they have analyzed a fossil of an extinct giant meat-eating bird — which they say could be the largest known member of its kind — providing new information about animal life in northern South America millions of years ago. The evidence lies in the leg bone […]
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Detailing organelle division and segregation in Plasmodium falciparum

The malaria-causing parasite, P. falciparum, replicates through schizogony, a tightly orchestrated process where numerous daughter parasites are formed simultaneously. Proper division and segregation of one-per-cell organelles, like the mitochondrion and apicoplast, are essential, yet remain poorly understood. We developed a new reporter parasite line that allows visualization of the mitochondrion in blood and mosquito stages. […]
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