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Cellectis and AstraZeneca in US$2.2bn deal
  1. Biotechnology

Cellectis and AstraZeneca in US$2.2bn deal

AstraZeneca plc has paid French cancer cell therapy developer Cellectis SA US$25m upfront and US$220m in equity in an US$2.2bn R&D deal for up to ten cell and gene therapies. Under the co-development agreement, that includes a US$80m equity investment and an option for a further equity investment of US$140m by AstraZeneca plc into Cellectis […]
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BioNtech reports Car-T/mRNA booster study results at ESMO
  1. Biotechnology

BioNtech reports Car-T/mRNA booster study results at ESMO

BioNtech SE has reported preliminary Phase I/II results with BNT211-01 (NEO-PTC-01) and CarVAC at ESMO conference in Madrid Testing different dose levels of its adoptive cell therapy BNT.221-01, a combination of Claudin 6 (CLDN6)-targeted Car-T cells (derived from NEO-PTC-01, initially developed by tody’s BioNTech subsidiary Neon Therapeutics) and the mRNA-based Car-T  booster CarVac (CAR-T cell […]
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Antiverse and GlobalBio Inc. extend collaboration
  1. Biotechnology

Antiverse and GlobalBio Inc. extend collaboration

Antiverse Ltd and GlobalBio Inc. have extend their cancer antibody partnership to progress two PD-1 modulators to preclinial development AI specialist Antiverse Ltd (Cardiff, UK) and antobody engeeniering expert GlobalBio, Inc. (New York, USA) will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy. The initial collaboration successfully resulted in the generation […]
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SpliceBio has made up a US $216m alliance with Spark Therapeutics
  1. Biotechnology

SpliceBio has made up a US $216m alliance with Spark Therapeutics

SpliceBio has licenced its intein technlogy to Roche’s gene therapy subsidiary Spark Therapeutics to develop a gene therapy targeting an undisclosed inherited retinal disease. Under a globally exclusive licence option agreement with Roche AG, SpliceBio secures an upfront payment, opt-in and milestone payments up to $216m plus royalties in exchange to its recombinant split […]
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A tiny ocean worm just revealed a big secret about how eyes evolve

A tiny ocean worm just revealed a big secret about how eyes evolve

A research team from the University of Vienna and the Alfred Wegener Institute in Bremerhaven has uncovered how the eyes of adult marine bristleworms continue to increase in size throughout their entire lifespan. The work shows that this constant growth is powered by a ring of neural stem cells that resembles similar structures found in […]
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Will Glacier Melt Lead to Increased Seismic Activity in Mountain Regions? – State of the Planet

A recent study from Earth and Planetary Science Letters is the first to directly link earthquakes to climate change-induced glacial melt. Scientists analyzed 15 years of seismic activity in the Grandes Jorasses—a peak that is part of the Mont Blanc massif between Italy and France—to better understand this association. This massif is one of the […]
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Worlwide

A tiny ocean worm just revealed a big secret about how eyes evolve

A tiny ocean worm just revealed a big secret about how eyes evolve

A research team from the University of Vienna and the Alfred Wegener Institute in Bremerhaven has uncovered how the eyes of adult marine bristleworms continue to increase in size throughout their entire lifespan. The work shows that this constant growth is powered by a ring of neural stem cells that resembles similar structures found in […]
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Will Glacier Melt Lead to Increased Seismic Activity in Mountain Regions? – State of the Planet

A recent study from Earth and Planetary Science Letters is the first to directly link earthquakes to climate change-induced glacial melt. Scientists analyzed 15 years of seismic activity in the Grandes Jorasses—a peak that is part of the Mont Blanc massif between Italy and France—to better understand this association. This massif is one of the […]
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