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Cellectis and AstraZeneca in US$2.2bn deal
  1. Biotechnology

Cellectis and AstraZeneca in US$2.2bn deal

AstraZeneca plc has paid French cancer cell therapy developer Cellectis SA US$25m upfront and US$220m in equity in an US$2.2bn R&D deal for up to ten cell and gene therapies. Under the co-development agreement, that includes a US$80m equity investment and an option for a further equity investment of US$140m by AstraZeneca plc into Cellectis […]
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BioNtech reports Car-T/mRNA booster study results at ESMO
  1. Biotechnology

BioNtech reports Car-T/mRNA booster study results at ESMO

BioNtech SE has reported preliminary Phase I/II results with BNT211-01 (NEO-PTC-01) and CarVAC at ESMO conference in Madrid Testing different dose levels of its adoptive cell therapy BNT.221-01, a combination of Claudin 6 (CLDN6)-targeted Car-T cells (derived from NEO-PTC-01, initially developed by tody’s BioNTech subsidiary Neon Therapeutics) and the mRNA-based Car-T  booster CarVac (CAR-T cell […]
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Antiverse and GlobalBio Inc. extend collaboration
  1. Biotechnology

Antiverse and GlobalBio Inc. extend collaboration

Antiverse Ltd and GlobalBio Inc. have extend their cancer antibody partnership to progress two PD-1 modulators to preclinial development AI specialist Antiverse Ltd (Cardiff, UK) and antobody engeeniering expert GlobalBio, Inc. (New York, USA) will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy. The initial collaboration successfully resulted in the generation […]
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SpliceBio has made up a US $216m alliance with Spark Therapeutics
  1. Biotechnology

SpliceBio has made up a US $216m alliance with Spark Therapeutics

SpliceBio has licenced its intein technlogy to Roche’s gene therapy subsidiary Spark Therapeutics to develop a gene therapy targeting an undisclosed inherited retinal disease. Under a globally exclusive licence option agreement with Roche AG, SpliceBio secures an upfront payment, opt-in and milestone payments up to $216m plus royalties in exchange to its recombinant split […]
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Disordered Interfacial Water Boosts Electrochemical C–C Coupling

In the relentless pursuit to combat climate change, the electrochemical conversion of carbon dioxide (CO₂) and carbon monoxide (CO) into value-added, energy-rich multi-carbon products has emerged as a beacon of hope. These processes promise not only to mitigate greenhouse gas emissions but also to create sustainable fuel alternatives that could revolutionize the energy landscape. However, […]
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Leveraging Next-Generation Tsunami Early Warning Systems to Save Lives – State of the Planet

Damage from the March 2011 tsunami in downtown Ofunato, Japan. Photo: U.S. Navy When an enormous 8.8 magnitude earthquake struck near Russia’s Kamchatka Peninsula, the impact reached far beyond its epicenter. In the passing hours, tsunami alerts were issued by several nations with coastlines along the Pacific Ocean’s Ring of Fire, prompting evacuations and escalating […]
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Worlwide

Disordered Interfacial Water Boosts Electrochemical C–C Coupling

In the relentless pursuit to combat climate change, the electrochemical conversion of carbon dioxide (CO₂) and carbon monoxide (CO) into value-added, energy-rich multi-carbon products has emerged as a beacon of hope. These processes promise not only to mitigate greenhouse gas emissions but also to create sustainable fuel alternatives that could revolutionize the energy landscape. However, […]
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Leveraging Next-Generation Tsunami Early Warning Systems to Save Lives – State of the Planet

Damage from the March 2011 tsunami in downtown Ofunato, Japan. Photo: U.S. Navy When an enormous 8.8 magnitude earthquake struck near Russia’s Kamchatka Peninsula, the impact reached far beyond its epicenter. In the passing hours, tsunami alerts were issued by several nations with coastlines along the Pacific Ocean’s Ring of Fire, prompting evacuations and escalating […]
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Crushing vs. Slashing: New skull scans reveal how giant dinosaurs killed

Crushing vs. Slashing: New skull scans reveal how giant dinosaurs killed

A new analysis of the bite strength of 18 species of carnivorous dinosaurs shows that while the Tyrannasaurus rex skull was optimized for quick, strong bites like a crocodile, other giant, predatory dinosaurs that walked on two legs — including spinosaurs and allosaurs — had much weaker bites and instead specialized in slashing and ripping […]
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