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Cellectis and AstraZeneca in US$2.2bn deal
  1. Biotechnology

Cellectis and AstraZeneca in US$2.2bn deal

AstraZeneca plc has paid French cancer cell therapy developer Cellectis SA US$25m upfront and US$220m in equity in an US$2.2bn R&D deal for up to ten cell and gene therapies. Under the co-development agreement, that includes a US$80m equity investment and an option for a further equity investment of US$140m by AstraZeneca plc into Cellectis […]
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BioNtech reports Car-T/mRNA booster study results at ESMO
  1. Biotechnology

BioNtech reports Car-T/mRNA booster study results at ESMO

BioNtech SE has reported preliminary Phase I/II results with BNT211-01 (NEO-PTC-01) and CarVAC at ESMO conference in Madrid Testing different dose levels of its adoptive cell therapy BNT.221-01, a combination of Claudin 6 (CLDN6)-targeted Car-T cells (derived from NEO-PTC-01, initially developed by tody’s BioNTech subsidiary Neon Therapeutics) and the mRNA-based Car-T  booster CarVac (CAR-T cell […]
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Antiverse and GlobalBio Inc. extend collaboration
  1. Biotechnology

Antiverse and GlobalBio Inc. extend collaboration

Antiverse Ltd and GlobalBio Inc. have extend their cancer antibody partnership to progress two PD-1 modulators to preclinial development AI specialist Antiverse Ltd (Cardiff, UK) and antobody engeeniering expert GlobalBio, Inc. (New York, USA) will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy. The initial collaboration successfully resulted in the generation […]
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SpliceBio has made up a US $216m alliance with Spark Therapeutics
  1. Biotechnology

SpliceBio has made up a US $216m alliance with Spark Therapeutics

SpliceBio has licenced its intein technlogy to Roche’s gene therapy subsidiary Spark Therapeutics to develop a gene therapy targeting an undisclosed inherited retinal disease. Under a globally exclusive licence option agreement with Roche AG, SpliceBio secures an upfront payment, opt-in and milestone payments up to $216m plus royalties in exchange to its recombinant split […]
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Scientists recreate life’s first step: Linking amino acids to RNA

Scientists recreate life’s first step: Linking amino acids to RNA

Chemists at UCL have shown how two of biology’s most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of life four billion years ago. Amino acids are the building blocks of proteins, the “workhorses” of life essential to nearly every living process. But proteins cannot replicate or […]
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Scientists recreate life’s first step: Linking amino acids to RNA

Scientists recreate life’s first step: Linking amino acids to RNA

Chemists at UCL have shown how two of biology’s most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of life four billion years ago. Amino acids are the building blocks of proteins, the “workhorses” of life essential to nearly every living process. But proteins cannot replicate or […]
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