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Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA — that molecular blueprint for life — over 70 years ago. Today, scientists are still uncovering new ways to read it. In 2010, Jianxin Ma, a professor of agronomy, and his collaborators built the first reference genome for soybeans on the widely studied […]
Separase regulates multiple aspects of the metaphase-to-anaphase transition. Separase cleaves cohesin to allow chromosome segregation and localizes to vesicles to promote exocytosis. The anaphase-promoting complex/cyclosome (APC/C) activates separase by ubiquitinating its inhibitory chaperone, securin, triggering its degradation. How this pathway controls the exocytic function of separase is unknown. During meiosis I, securin is degraded over […]

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Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA — that molecular blueprint for life — over 70 years ago. Today, scientists are still uncovering new ways to read it. In 2010, Jianxin Ma, a professor of agronomy, and his collaborators built the first reference genome for soybeans on the widely studied […]
Separase regulates multiple aspects of the metaphase-to-anaphase transition. Separase cleaves cohesin to allow chromosome segregation and localizes to vesicles to promote exocytosis. The anaphase-promoting complex/cyclosome (APC/C) activates separase by ubiquitinating its inhibitory chaperone, securin, triggering its degradation. How this pathway controls the exocytic function of separase is unknown. During meiosis I, securin is degraded over […]
Columbia’s Sabin Center for Climate Change Law focuses on four program areas: cross-cutting issues and initiatives, energy law, environmental and land use law, and international and foreign law. As the number of legal efforts involving each of these categories continues to grow, the center has positioned itself as a resource hub for tracking and analyzing […]

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