Life Sciences A user manual for yeast’s genetic switches When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. A Kobe University team found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production. It’s said that DNA is the blueprint […] Written by Admin December 28, 2024December 28, 2024 Saving Bookmark this article Bookmarked
Depemokimab Applications Accepted for Review by the US FDA for Asthma with Type 2 Inflammation and for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) London, UK — 03 March 2025 — GSK plc (LSE/NYSE: GSK) today announced the US Food and Drug Administration (FDA) has accepted for review the Biologics License Application for the use of depemokimab in two indications. The proposed indications are… Written by Admin March 7, 2025March 7, 2025 Saving Bookmark this article Bookmarked
Ca 2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors Membrane contact sites (MCS) between the plasma membrane (PM) and endoplasmic reticulum (ER) regulate Ca2+ influx. However, the mechanisms by which cells modulate ER–PM MCS density are not understood, and the role of Ca2+, if any, in regulating these is unknown. We report that in Drosophila photoreceptors, MCS density is regulated by the Ca2+ channels, […] Written by Admin March 6, 2025March 6, 2025 Saving Bookmark this article Bookmarked
Depemokimab Applications Accepted for Review by the US FDA for Asthma with Type 2 Inflammation and for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) London, UK — 03 March 2025 — GSK plc (LSE/NYSE: GSK) today announced the US Food and Drug Administration (FDA) has accepted for review the Biologics License Application for the use of depemokimab in two indications. The proposed indications are… Written by Admin March 7, 2025March 7, 2025 Saving Bookmark this article Bookmarked
Ca 2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors Membrane contact sites (MCS) between the plasma membrane (PM) and endoplasmic reticulum (ER) regulate Ca2+ influx. However, the mechanisms by which cells modulate ER–PM MCS density are not understood, and the role of Ca2+, if any, in regulating these is unknown. We report that in Drosophila photoreceptors, MCS density is regulated by the Ca2+ channels, […] Written by Admin March 6, 2025March 6, 2025 Saving Bookmark this article Bookmarked
Irish flax in resilient food systems It’s not just linnets who are flocking to the fields once more. Neighbours, family, retired growers, and textile makers pass each other regularly on the narrow lane up to Mallon Farm. Community Having previously found farming a lonely business, the interest and support from others have been highlights for Helen. As well as company, these […] Written by brendan March 6, 2025March 6, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked
