Biotechnology Tetraspecific B/NK cell better than T cell engagers The therapeutic landscape for relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) is evolving toward targeted T-cell based immunotherapies, including CD19-targeted CAR-T and CD3xCD20 T-cell engaging (TCE) bispecificantibodies. Yet, there remains an unmet medical need for patients who are refractory to, or ineligible for these treatments. Leveraging natural killer NK cells emerges as a promising […] Written by Thomas Gabrielczyk November 16, 2024November 16, 2024 Saving Bookmark this article Bookmarked
UK biotech defies the odds, raising £3.5B in 2024 Newsletter Signup – Under Article / In Page “*” indicates required fields The past year has been one of ups and downs for the biotech and healthcare sectors in the U.K. A report by the UK BioIndustry Association (BIA) revealed how investments played a part in research and development (R&D) in the country. Equity financing […] Written by Roohi Mariam Peter February 1, 2025February 1, 2025 Saving Bookmark this article Bookmarked
Sphingolipid metabolism orchestrates establishment of the hair follicle stem cell compartment Sphingolipids serve as building blocks of membranes to ensure subcellular compartmentalization and facilitate intercellular communication. How cell type–specific lipid compositions are achieved and what is their functional significance in tissue morphogenesis and maintenance has remained unclear. Here, we identify a stem cell–specific role for ceramide synthase 4 (CerS4) in orchestrating fate decisions in skin epidermis. […] Written by Admin January 31, 2025January 31, 2025 Saving Bookmark this article Bookmarked
UK biotech defies the odds, raising £3.5B in 2024 Newsletter Signup – Under Article / In Page “*” indicates required fields The past year has been one of ups and downs for the biotech and healthcare sectors in the U.K. A report by the UK BioIndustry Association (BIA) revealed how investments played a part in research and development (R&D) in the country. Equity financing […] Written by Roohi Mariam Peter February 1, 2025February 1, 2025 Saving Bookmark this article Bookmarked
Sphingolipid metabolism orchestrates establishment of the hair follicle stem cell compartment Sphingolipids serve as building blocks of membranes to ensure subcellular compartmentalization and facilitate intercellular communication. How cell type–specific lipid compositions are achieved and what is their functional significance in tissue morphogenesis and maintenance has remained unclear. Here, we identify a stem cell–specific role for ceramide synthase 4 (CerS4) in orchestrating fate decisions in skin epidermis. […] Written by Admin January 31, 2025January 31, 2025 Saving Bookmark this article Bookmarked
A Climate Change Adaptation Expert on How To Reduce Fire Risk – State of the Planet The Palisades Fire in Los Angeles. Photo: CAL FIRE_Official In light of the recent Los Angeles fires, a 2023 Columbia Climate School and Headwaters Economics report on wildfire mitigation strategies provides valuable insight into what’s needed to reduce fire risk and how it might be done. According to the report, wildfires have always occurred naturally […] Written by Renée Cho January 31, 2025January 31, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked
