technology

BioNtech reports Car-T/mRNA booster study results at ESMO
  1. Biotechnology

BioNtech reports Car-T/mRNA booster study results at ESMO

BioNtech SE has reported preliminary Phase I/II results with BNT211-01 (NEO-PTC-01) and CarVAC at ESMO conference in Madrid Testing different dose levels of its adoptive cell therapy BNT.221-01, a combination of Claudin 6 (CLDN6)-targeted Car-T cells (derived from NEO-PTC-01, initially developed by tody’s BioNTech subsidiary Neon Therapeutics) and the mRNA-based Car-T  booster CarVac (CAR-T cell […]
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Antiverse and GlobalBio Inc. extend collaboration
  1. Biotechnology

Antiverse and GlobalBio Inc. extend collaboration

Antiverse Ltd and GlobalBio Inc. have extend their cancer antibody partnership to progress two PD-1 modulators to preclinial development AI specialist Antiverse Ltd (Cardiff, UK) and antobody engeeniering expert GlobalBio, Inc. (New York, USA) will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy. The initial collaboration successfully resulted in the generation […]
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SpliceBio has made up a US $216m alliance with Spark Therapeutics
  1. Biotechnology

SpliceBio has made up a US $216m alliance with Spark Therapeutics

SpliceBio has licenced its intein technlogy to Roche’s gene therapy subsidiary Spark Therapeutics to develop a gene therapy targeting an undisclosed inherited retinal disease. Under a globally exclusive licence option agreement with Roche AG, SpliceBio secures an upfront payment, opt-in and milestone payments up to $216m plus royalties in exchange to its recombinant split […]
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High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation

Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […]
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The hidden harm from salmon farming

In addition to parasites, pathogens, chemical residues, and other treatments can persist in cages. Fallow sites are expected to undergo complete removal of fish and nets to limit pathogen carryover. Campaigners, however, say the Aird site “continued functioning as a reservoir of disease and flesh-eating lice.” Read: The catch. Unsustainable Abigail Penny, executive director of […]
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Worlwide

High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation

Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […]
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The hidden harm from salmon farming

In addition to parasites, pathogens, chemical residues, and other treatments can persist in cages. Fallow sites are expected to undergo complete removal of fish and nets to limit pathogen carryover. Campaigners, however, say the Aird site “continued functioning as a reservoir of disease and flesh-eating lice.” Read: The catch. Unsustainable Abigail Penny, executive director of […]
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Doomed ants send a final scent to save their colony

Doomed ants send a final scent to save their colony

Ant societies behave like tightly integrated “superorganisms,” where thousands of individuals work together in a way that resembles the coordinated activity of cells in a body. Researchers at the Institute of Science and Technology Austria (ISTA) have found that terminally ill ant brood release a distinctive odor, similar to the way infected body cells send […]
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