Biotechnology BioNtech reports Car-T/mRNA booster study results at ESMO BioNtech SE has reported preliminary Phase I/II results with BNT211-01 (NEO-PTC-01) and CarVAC at ESMO conference in Madrid Testing different dose levels of its adoptive cell therapy BNT.221-01, a combination of Claudin 6 (CLDN6)-targeted Car-T cells (derived from NEO-PTC-01, initially developed by tody’s BioNTech subsidiary Neon Therapeutics) and the mRNA-based Car-T booster CarVac (CAR-T cell […] Written by BIOCOM AG October 27, 2023October 27, 2023 Saving Bookmark this article Bookmarked
Biotechnology Antiverse and GlobalBio Inc. extend collaboration Antiverse Ltd and GlobalBio Inc. have extend their cancer antibody partnership to progress two PD-1 modulators to preclinial development AI specialist Antiverse Ltd (Cardiff, UK) and antobody engeeniering expert GlobalBio, Inc. (New York, USA) will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy. The initial collaboration successfully resulted in the generation […] Written by BIOCOM AG October 21, 2023October 21, 2023 Saving Bookmark this article Bookmarked
Biotechnology SpliceBio has made up a US $216m alliance with Spark Therapeutics SpliceBio has licenced its intein technlogy to Roche’s gene therapy subsidiary Spark Therapeutics to develop a gene therapy targeting an undisclosed inherited retinal disease. Under a globally exclusive licence option agreement with Roche AG, SpliceBio secures an upfront payment, opt-in and milestone payments up to $216m plus royalties in exchange to its recombinant split […] Written by BIOCOM AG October 18, 2023October 18, 2023 Saving Bookmark this article Bookmarked
Microbes in mouth reflect lifestyle choices Lifestyle can shape the composition of beneficial bacteria and other microorganisms within the mouth, according to a new study led by Penn State biologists. The international team revealed how the “oral microbiome” differs over a range of subsistence strategies — from nomadic hunter gatherers to farmers to industrialized groups — and found that lifestyle, as […] Written by Admin November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Fossil of huge terror bird offers new information about wildlife in South America 12 million years ago Researchers including a Johns Hopkins University evolutionary biologist report they have analyzed a fossil of an extinct giant meat-eating bird — which they say could be the largest known member of its kind — providing new information about animal life in northern South America millions of years ago. The evidence lies in the leg bone […] Written by Admin November 5, 2024November 5, 2024 Saving Bookmark this article Bookmarked
Microbes in mouth reflect lifestyle choices Lifestyle can shape the composition of beneficial bacteria and other microorganisms within the mouth, according to a new study led by Penn State biologists. The international team revealed how the “oral microbiome” differs over a range of subsistence strategies — from nomadic hunter gatherers to farmers to industrialized groups — and found that lifestyle, as […] Written by Admin November 6, 2024November 6, 2024 Saving Bookmark this article Bookmarked
Fossil of huge terror bird offers new information about wildlife in South America 12 million years ago Researchers including a Johns Hopkins University evolutionary biologist report they have analyzed a fossil of an extinct giant meat-eating bird — which they say could be the largest known member of its kind — providing new information about animal life in northern South America millions of years ago. The evidence lies in the leg bone […] Written by Admin November 5, 2024November 5, 2024 Saving Bookmark this article Bookmarked
Detailing organelle division and segregation in Plasmodium falciparum The malaria-causing parasite, P. falciparum, replicates through schizogony, a tightly orchestrated process where numerous daughter parasites are formed simultaneously. Proper division and segregation of one-per-cell organelles, like the mitochondrion and apicoplast, are essential, yet remain poorly understood. We developed a new reporter parasite line that allows visualization of the mitochondrion in blood and mosquito stages. […] Written by Admin November 4, 2024November 4, 2024 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked