Life Sciences Viral ‘backbone’ underlies variation in rotavirus vaccine effectiveness Researchers have shown that differences in the entire rotavirus genome — not just its two surface proteins — affect how well vaccines work, helping to explain why some strains are more likely to infect vaccinated individuals. The study, published today as a Reviewed Preprint in eLife, is described by the editors as an important paper. […] Written by Admin April 8, 2025April 8, 2025 Saving Bookmark this article Bookmarked
Hornet-eating frog shows remarkable venom resistance A frog with an unexpectedly strong resistance to venom has been identified, and it routinely eats hornets despite the insects’ dangerous stingers. Researchers believe this species may become a useful model organism for exploring how animals develop tolerance to venom. For many people, even glimpsing a hornet’s stinger is enough to cause alarm. Yet certain […] Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked
High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Hornet-eating frog shows remarkable venom resistance A frog with an unexpectedly strong resistance to venom has been identified, and it routinely eats hornets despite the insects’ dangerous stingers. Researchers believe this species may become a useful model organism for exploring how animals develop tolerance to venom. For many people, even glimpsing a hornet’s stinger is enough to cause alarm. Yet certain […] Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked
High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
The hidden harm from salmon farming In addition to parasites, pathogens, chemical residues, and other treatments can persist in cages. Fallow sites are expected to undergo complete removal of fish and nets to limit pathogen carryover. Campaigners, however, say the Aird site “continued functioning as a reservoir of disease and flesh-eating lice.” Read: The catch. Unsustainable Abigail Penny, executive director of […] Written by brendan December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked