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What began in the labs of the University of Queensland has now set the stage for one of Europe’s largest biotech acquisitions of the year. Sanofi has announced it will acquire UK-based vaccine developer Vicebio for $1.15 billion upfront, with an additional $450 million tied to clinical milestones—underscoring a major commitment to next-generation respiratory vaccines. […]
Excess centrosomes cause defects in mitosis, cell-signaling, and cell migration, and therefore their assembly is tightly regulated. The divergent Polo kinase, PLK4, controls centriole duplication at the heart of centrosome assembly, and elevated PLK4 levels promote centrosome amplification (CA), a founding event of tumorigenesis. Here, we investigate the transcriptional consequences of elevated PLK4 and find […]

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What began in the labs of the University of Queensland has now set the stage for one of Europe’s largest biotech acquisitions of the year. Sanofi has announced it will acquire UK-based vaccine developer Vicebio for $1.15 billion upfront, with an additional $450 million tied to clinical milestones—underscoring a major commitment to next-generation respiratory vaccines. […]
Excess centrosomes cause defects in mitosis, cell-signaling, and cell migration, and therefore their assembly is tightly regulated. The divergent Polo kinase, PLK4, controls centriole duplication at the heart of centrosome assembly, and elevated PLK4 levels promote centrosome amplification (CA), a founding event of tumorigenesis. Here, we investigate the transcriptional consequences of elevated PLK4 and find […]

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