Biology Engineering Breast Cancer Cells for Tumor Vaccines In the rapidly evolving landscape of cancer immunotherapy, a groundbreaking study has emerged from the laboratories of Martí-Díaz et al., poised to redefine therapeutic strategies for breast cancer. Published in the prestigious journal BMC Cancer, this research delves into the sophisticated engineering of phagocytic signals on breast cancer cells ex vivo, proposing a novel whole […] Written by Bioengineer July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked Biotechnology 5 biotech companies making waves in Wales in 2025 Newsletter Signup – Under Article / In Page “*” indicates required fields Famous for its rugged coastline and scenic mountains, Wales is also home to a thriving life science industry. Supported by science parks, med-tech companies, and universities, the country has opened up avenues for a budding biotech sector, particularly for the development of startups. […] Written by Roohi Mariam Peter July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked Environmental Science Highlights From MR2025 – State of the Planet In mid-June, over 400 academics, policymakers and practitioners attended MR2025: Mobility, Adaptation, and Wellbeing in a Changing Climate, hosted by the Columbia Climate School in partnership with the Global Centre for Climate Mobility and the Tamer Institute for Social Enterprise and Climate Change. Since its inception in 2019, the conference has convened every two years […] Written by Guest July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked Life Sciences Scientists reprogram ant behavior using brain molecules From the bright lights of cities that don’t sleep — where people hustle and bustle through the night to keep subways, servers, and supply chains alive — to the whisper-dark understory of tropical forests where ants hum in syncopated lines, the planet’s most intricate societies hinge on round-the-clock cooperation and finely tuned roles. Within Atta […] Written by Admin July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked Life Sciences Mammals didn’t walk upright until late—here’s what fossils reveal For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […] Written by Admin June 30, 2025June 30, 2025 Saving Bookmark this article Bookmarked Biology A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked Environmental Science ‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked Life Sciences Skull study shows Chicago’s rodents are rapidly evolving In general, evolution is a long, slow process of tiny changes passed down over generations, resulting in new adaptations and even new species over thousands or millions of years. But when living things are faced with dramatic shifts in the world around them, they sometimes rapidly adapt to better survive. Scientists recently found an example […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked Biotechnology EU Commissioner Várhelyi revives Biotech Act for 2025 In a panel discussion at Medicines for Europe Annual Conference, EU Health Commissioner Olivér Várhelyi made a surprise announcement that the Commission will adopt the EU Biotech Act by the end of this year, citing growing “global challenges”. According to the EU Commission’s work programme, the legislation was initially scheduled for adoption in Q3 2025, […] Written by Thomas Gabrielczyk June 28, 2025June 28, 2025 Saving Bookmark this article Bookmarked Life Sciences These 545-million-year-old fossil trails just rewrote the story of evolution The Cambrian explosion was an extraordinary phenomenon in the evolution of life on the planet that led to the emergence of many animal phyla and the diversification of species. During this period, some 530 million years ago, most of the basic body plans of organisms that have survived to the present day emerged. However, this […] Written by Admin June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked Biology Consortium Seeks to Launch Major Carbon Removal Initiatives Experts in the field of carbon capture and climate solutions are coming together for a pivotal meeting in Exeter, aimed at spearheading the development of a new carbon economy. The New Carbon Economy Consortium (NCEC), a key player in the global effort to manage carbon emissions, will host its annual meeting at the University of […] Written by Bioengineer June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Biology Engineering Breast Cancer Cells for Tumor Vaccines In the rapidly evolving landscape of cancer immunotherapy, a groundbreaking study has emerged from the laboratories of Martí-Díaz et al., poised to redefine therapeutic strategies for breast cancer. Published in the prestigious journal BMC Cancer, this research delves into the sophisticated engineering of phagocytic signals on breast cancer cells ex vivo, proposing a novel whole […] Written by Bioengineer July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked
Biotechnology 5 biotech companies making waves in Wales in 2025 Newsletter Signup – Under Article / In Page “*” indicates required fields Famous for its rugged coastline and scenic mountains, Wales is also home to a thriving life science industry. Supported by science parks, med-tech companies, and universities, the country has opened up avenues for a budding biotech sector, particularly for the development of startups. […] Written by Roohi Mariam Peter July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked
Environmental Science Highlights From MR2025 – State of the Planet In mid-June, over 400 academics, policymakers and practitioners attended MR2025: Mobility, Adaptation, and Wellbeing in a Changing Climate, hosted by the Columbia Climate School in partnership with the Global Centre for Climate Mobility and the Tamer Institute for Social Enterprise and Climate Change. Since its inception in 2019, the conference has convened every two years […] Written by Guest July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked
Life Sciences Scientists reprogram ant behavior using brain molecules From the bright lights of cities that don’t sleep — where people hustle and bustle through the night to keep subways, servers, and supply chains alive — to the whisper-dark understory of tropical forests where ants hum in syncopated lines, the planet’s most intricate societies hinge on round-the-clock cooperation and finely tuned roles. Within Atta […] Written by Admin July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked
Life Sciences Mammals didn’t walk upright until late—here’s what fossils reveal For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […] Written by Admin June 30, 2025June 30, 2025 Saving Bookmark this article Bookmarked
Biology A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Environmental Science ‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Life Sciences Skull study shows Chicago’s rodents are rapidly evolving In general, evolution is a long, slow process of tiny changes passed down over generations, resulting in new adaptations and even new species over thousands or millions of years. But when living things are faced with dramatic shifts in the world around them, they sometimes rapidly adapt to better survive. Scientists recently found an example […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Biotechnology EU Commissioner Várhelyi revives Biotech Act for 2025 In a panel discussion at Medicines for Europe Annual Conference, EU Health Commissioner Olivér Várhelyi made a surprise announcement that the Commission will adopt the EU Biotech Act by the end of this year, citing growing “global challenges”. According to the EU Commission’s work programme, the legislation was initially scheduled for adoption in Q3 2025, […] Written by Thomas Gabrielczyk June 28, 2025June 28, 2025 Saving Bookmark this article Bookmarked
Life Sciences These 545-million-year-old fossil trails just rewrote the story of evolution The Cambrian explosion was an extraordinary phenomenon in the evolution of life on the planet that led to the emergence of many animal phyla and the diversification of species. During this period, some 530 million years ago, most of the basic body plans of organisms that have survived to the present day emerged. However, this […] Written by Admin June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Biology Consortium Seeks to Launch Major Carbon Removal Initiatives Experts in the field of carbon capture and climate solutions are coming together for a pivotal meeting in Exeter, aimed at spearheading the development of a new carbon economy. The New Carbon Economy Consortium (NCEC), a key player in the global effort to manage carbon emissions, will host its annual meeting at the University of […] Written by Bioengineer June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked