Biology Directed stochasticity: Building biomolecular condensates in the right place Controlling biomolecular condensate formation within the nucleus is critical for genome function. In this issue, Xu et al. (https://doi.org/10.1083/jcb.202401036) report that KPNA3 promotes histone locus body formation and expression of replication-dependent histone genes by both importing NPAT into the nucleus and preventing NPAT condensation from improperly occurring in the cytoplasm. Written by Admin December 26, 2024December 26, 2024 Saving Bookmark this article Bookmarked
Environmental Science Reflecting on COP29 and the Need for Radical Collaboration – State of the Planet The author, left, and filmmaker Sumit Rezwan Shahriar, at COP29 My journey from New York City to Baku, Azerbaijan, host of this year’s UN climate change conference (COP29), took me over seven thousand miles of earth and sea. I arrived in Baku at night, where colorful, flame-shaped towers define the landscape of this city. Once […] Written by Guest December 26, 2024December 26, 2024 Saving Bookmark this article Bookmarked
Biotechnology Merry Christmas and a Happy New Year European Biotechnology wishes its readers a Merry Christmas and a Happy New Year! We are taking a short winter break and will be back in January 2025 to provide you with the latest news, background reports, personalia and – in cooperation with our new partner, the Society for Laboratory Automation & Screening (SLAS) – updates […] Written by Thomas Gabrielczyk December 26, 2024December 26, 2024 Saving Bookmark this article Bookmarked
Life Sciences Fly vs. wasp: Stealing a defense move helps thwart a predator In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition. But sometimes, as in the corporate world, outright theft can be a quicker way to achieve dominance. University of California, Berkeley biologists have shown that several species of […] Written by Admin December 26, 2024December 26, 2024 Saving Bookmark this article Bookmarked
Life Sciences Pollinators most vulnerable to rising global temperatures are flies, study shows Despite their reputation as buzzing nuisances, flies serve a critical role as some of the Earth’s most prolific pollinators — and new research led by Penn State scientists suggests they are increasingly at risk due to rising global temperatures. In a study recently published in the Journal of Melittology, an international team of researchers looked […] Written by Admin December 25, 2024December 25, 2024 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development U.S. Food and Drug Administration Issues Complete Response Letter for the Glepaglutide New Drug Application for the Treatment of Short Bowel Syndrome Copenhagen, Denmark, December 19, 2024 – Zealand Pharma A/S (Nasdaq: ZEAL) (“Zealand”) (CVR-no. 20045078), a biotechnology company focused on the discovery and development of innovative peptide-based medicines, today announced that… Written by Admin December 25, 2024December 25, 2024 Saving Bookmark this article Bookmarked
Biology Functionally conserved inner mitochondrial membrane proteins CCDC51 and Mdm33 demarcate a subset of fission events While extensive work has examined the mechanisms of mitochondrial fission, it remains unclear whether internal mitochondrial proteins in metazoans play a direct role in the process. Previously, the yeast inner membrane protein Mdm33 was shown to be required for normal mitochondrial morphology and has been hypothesized to be involved in mitochondrial fission. However, it is […] Written by Admin December 25, 2024December 25, 2024 Saving Bookmark this article Bookmarked
Environmental Science China syndrome? Donald Trump has, of course, threatened a far broader trade war against China, claiming he would impose 100 per cent tariffs on Chinese products, but, as we’ve suggested before, this looks more like the opening round in a negotiating position than a firm commitment. Certainly his senior advisors and others close to him, but also more […] Written by brendan December 25, 2024December 25, 2024 Saving Bookmark this article Bookmarked
Life Sciences Growing safer spuds: Removing toxins from potatoes Scientists have discovered a way to remove toxic compounds from potatoes, making them safer to eat and easier to store. The breakthrough could cut food waste and enhance crop farming in space and other extreme environments. Potato plants naturally produce chemicals that protect them from insects. The chemicals, called steroidal glycoalkaloids, or SGAs, are found […] Written by Admin December 24, 2024December 24, 2024 Saving Bookmark this article Bookmarked
Life Sciences Programming cells: Revolutionizing genetic circuits with cutting-edge RNA tools Professor Jongmin Kim’s research team at POSTECH developed a new technology that improves the precision and integration density of synthetic genetic circuits. The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the ‘Synthetic Translational Coupling Element […] Written by Admin December 23, 2024December 23, 2024 Saving Bookmark this article Bookmarked
Biotechnology Ionis gets a milestone approval; Another top FDA official to step down The clearance of Tryngolza gives Ionis its first wholly-owned, marketed medicine. Elsewhere, Robert Temple became the latest FDA leader to leave the agency, and two biotechs cut research deals. Written by BioPharma Dive staff December 23, 2024December 23, 2024 Saving Bookmark this article Bookmarked
Environmental Science Columbia Climate School Delegates Reflect on COP29 – State of the Planet Last month, more than 50,000 people from 200 countries gathered for the 29th U.N. Climate Change Conference of the Parties (COP29) in Baku, Azerbaijan. For two weeks, global leaders, academics, scientists, public citizens, activists and nonprofit organizations from around the world came together to address the growing challenges and potential solutions to climate change. […] Written by Columbia Climate School December 23, 2024December 23, 2024 Saving Bookmark this article Bookmarked