Biology

  1. Biology

Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends

Centrioles are microtubule-based organelles required for the formation of centrosomes and cilia. Centriolar microtubules, unlike their cytosolic counterparts, are stable and grow very slowly, but the underlying mechanisms are poorly understood. Here, we reconstituted in vitro the interplay between the proteins that cap distal centriole ends and control their elongation: CP110, CEP97, and CPAP/SAS-4. We […]
Written by
  1. Biology

Pregnancy May Heighten Mental Health Risks for Individuals with MS

Pregnant People with Multiple Sclerosis Are at Increased Risk for Mental Illness Recent studies have raised alarm bells about the mental health implications faced by pregnant individuals diagnosed with multiple sclerosis (MS). A comprehensive study, published in the esteemed journal Neurology, emphasizes the fact that expectant parents with MS are significantly more susceptible to mental […]
Written by
  1. Biology

The KNL-1/Knl1 outer kinetochore protein caught regulating F-actin

Kinetochores are multiprotein complexes that link chromosomes to microtubules and are essential for chromosome segregation during cell divisions. In this issue, Alves Domingos et al. (https://doi.org/10.1083/jcb.202311147) show that the conserved KNL-1/Knl1 protein of the Knl1/Mis12/Ndc80 (KMN) outer kinetochore complex postmitotically regulates F-actin to shape somatosensory dendrites.
Written by
  1. Biology

Harnessing Ion-Controlled Spin Wave Interference

In a groundbreaking advancement that pushes the boundaries of artificial intelligence technology, a collaborative research endeavor led by the National Institute for Materials Science (NIMS) and the Japan Fine Ceramics Center (JFCC) has unveiled a pioneering AI device featuring an iono-magnonic reservoir. This device distinctly exemplifies a significant upgrade in the existing physical reservoir computing […]
Written by
  1. Biology

Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle

TPX2 is an elongated molecule containing multiple α-helical repeats. It stabilizes microtubules (MTs), promotes MT nucleation, and is essential for spindle assembly. However, the molecular basis of how TPX2 performs these functions remains elusive. Here, we systematically characterized the MT-binding activities of all TPX2 modules individually and in combinations and investigated their respective contributions both […]
Written by
  1. Biology

Machine Learning Surpasses Traditional Statistical Approaches in Tackling

Researchers from the National Institute of Health Data Science at Peking University have brought forth a groundbreaking systematic review that evaluates strategies for dealing with missing data in electronic health records (EHRs). This study, published in the esteemed journal Health Data Science, represents a significant move toward understanding and utilizing modern machine learning methods in […]
Written by
  1. Biology

Quantitative imaging of loop extruders rebuilding interphase genome architecture after mitosis

How cells establish the interphase genome organization after mitosis is incompletely understood. Using quantitative and super-resolution microscopy, we show that the transition from a Condensin to a Cohesin-based genome organization occurs dynamically over 2 h. While a significant fraction of Condensins remains chromatin-bound until early G1, Cohesin-STAG1 and its boundary factor CTCF are rapidly imported […]
Written by
  1. Biology

Scientists Develop Bacteria-Repellent Surfaces That Promote Cell Growth

image:  The team have shown that their nanostructured surfaces resist the growth of bacteria, but enable the culturing of cells. view more  Credit: Tokyo Metropolitan University Tokyo, Japan – Researchers from Tokyo Metropolitan University have created nanostructured alumina surfaces which are strongly antibacterial but can be used to culture cells. They found that anodic porous […]
Written by
  1. Biology

Global Research Alliance Aims to Create Enhanced Dietary Supplement for

In a groundbreaking initiative addressing one of the most pressing challenges in maternal and child health, researchers from Kenya, Norway, and Denmark have come together to create and test an advanced dietary supplement specifically aimed at pregnant women. This project, termed ‘Mother’s Micronutrient Supplement for Pregnancy and Lactation’ (MoMS), seeks to combat the detrimental effects […]
Written by

Good Reads

Six Exposure Science Principles Advancing Healthy Environments

Six Exposure Science Principles Advancing Healthy Environments

In the evolving landscape of environmental health, understanding the intricate ways in which humans interact with their surroundings is paramount. Exposure science, a discipline that discerns how individuals come into contact with environmental agents, stands at the forefront of this endeavor. A recent seminal publication by E.A. Cohen Hubal delineates six foundational principles of exposure […]
Written by
The fatal mutation that lets cancer outsmart the human immune system

The fatal mutation that lets cancer outsmart the human immune system

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates. This insight could lead to more powerful cancer treatments. The study was published in Nature Communications. It revealed a tiny genetic difference […]
Written by

Worlwide

Six Exposure Science Principles Advancing Healthy Environments

Six Exposure Science Principles Advancing Healthy Environments

In the evolving landscape of environmental health, understanding the intricate ways in which humans interact with their surroundings is paramount. Exposure science, a discipline that discerns how individuals come into contact with environmental agents, stands at the forefront of this endeavor. A recent seminal publication by E.A. Cohen Hubal delineates six foundational principles of exposure […]
Written by
The fatal mutation that lets cancer outsmart the human immune system

The fatal mutation that lets cancer outsmart the human immune system

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates. This insight could lead to more powerful cancer treatments. The study was published in Nature Communications. It revealed a tiny genetic difference […]
Written by

Creating Your Unique Round Stamps Online: Reduce Expenses and Time for Your Business with Our Personalized Stamp Solution

Guidelines for Designing Round Stamps Online: Maximize Time and Savings for Your Firm with Our Unique Stamp Creator Advantages of Utilizing an Online Stamp Maker? With the advent of online stamp creation tools, making stamps is now more accessible than ever. Whether you need a stamp for your business or home use, these tools offer […]
Written by

Trending

Login

Welcome to Life Science News!
"Explore the Latest Discoveries and Breakthroughs in Life Science with Life Science News!"
Read Smart, Save Time
Pick all the topics you are interested in to fill your homepage with stories you'll love.
Join our community
Registration is closed.