Biology

  1. Biology

Global Research Alliance Aims to Create Enhanced Dietary Supplement for

In a groundbreaking initiative addressing one of the most pressing challenges in maternal and child health, researchers from Kenya, Norway, and Denmark have come together to create and test an advanced dietary supplement specifically aimed at pregnant women. This project, termed ‘Mother’s Micronutrient Supplement for Pregnancy and Lactation’ (MoMS), seeks to combat the detrimental effects […]
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  1. Biology

MYO18B promotes lysosomal exocytosis by facilitating focal adhesion maturation

Many cancer cells exhibit increased amounts of paucimannose glycans, which are truncated N-glycan structures rarely found in mammals. Paucimannosidic proteins are proposedly generated within lysosomes and exposed on the cell surface through a yet uncertain mechanism. In this study, we revealed that paucimannosidic proteins are produced by lysosomal glycosidases and secreted via lysosomal exocytosis. Interestingly, […]
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  1. Biology

Updated Protocols for Managing Blood Cancers During Pregnancy

A groundbreaking set of guidelines has emerged to navigate the complexities of diagnosing and managing serious blood cancers during pregnancy. The prevalence of blood cancers, such as acute leukemia and aggressive lymphomas, although rare, is on the rise, affecting approximately 12.5 pregnancies per 100,000. This increasing incidence can be attributed to several factors, including the […]
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  1. Biology

ATG9A facilitates the closure of mammalian autophagosomes

Canonical autophagy captures within specialized double-membrane organelles, termed autophagosomes, an array of cytoplasmic components destined for lysosomal degradation. An autophagosome is completed when the growing phagophore undergoes ESCRT-dependent membrane closure, a prerequisite for its subsequent fusion with endolysosomal organelles and degradation of the sequestered cargo. ATG9A, a key integral membrane protein of the autophagy pathway, […]
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  1. Biology

Promoting Bone Regeneration and Adhesion Using Safe Visible Light

In a remarkable advancement in the field of bone regeneration, a dedicated team of researchers from POSTECH has unveiled a pioneering injectable adhesive hydrogel. Spearheaded by Professor Hyung Joon Cha from the Department of Chemical Engineering and the Graduate School of Convergence Science and Technology, this innovative hydrogel technology is engineered to facilitate effective bone […]
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  1. Biology

An interkinetic envelope surrounds chromosomes between meiosis I and II in C. elegans oocytes

At the end of cell division, the nuclear envelope reassembles around the decondensing chromosomes. Female meiosis culminates in two consecutive cell divisions of the oocyte, meiosis I and II, which are separated by a brief transition phase known as interkinesis. Due to the absence of chromosome decondensation and the suppression of genome replication during interkinesis, […]
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  1. Biology

Directed stochasticity: Building biomolecular condensates in the right place

Controlling biomolecular condensate formation within the nucleus is critical for genome function. In this issue, Xu et al. (https://doi.org/10.1083/jcb.202401036) report that KPNA3 promotes histone locus body formation and expression of replication-dependent histone genes by both importing NPAT into the nucleus and preventing NPAT condensation from improperly occurring in the cytoplasm.
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  1. Biology

Functionally conserved inner mitochondrial membrane proteins CCDC51 and Mdm33 demarcate a subset of fission events

While extensive work has examined the mechanisms of mitochondrial fission, it remains unclear whether internal mitochondrial proteins in metazoans play a direct role in the process. Previously, the yeast inner membrane protein Mdm33 was shown to be required for normal mitochondrial morphology and has been hypothesized to be involved in mitochondrial fission. However, it is […]
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Robotic Probe Rapidly Assesses Essential Properties of Novel Materials

In the quest to conquer the limitations of semiconductor materials and their application in solar technologies, a pioneering research team at the Massachusetts Institute of Technology (MIT) has developed an innovative autonomous robotic system. This advancement comes at a crucial time when the demand for efficient energy sources continues to rise. Researchers face significant bottlenecks […]
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Robotic Probe Rapidly Assesses Essential Properties of Novel Materials

In the quest to conquer the limitations of semiconductor materials and their application in solar technologies, a pioneering research team at the Massachusetts Institute of Technology (MIT) has developed an innovative autonomous robotic system. This advancement comes at a crucial time when the demand for efficient energy sources continues to rise. Researchers face significant bottlenecks […]
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600-million-year-old body blueprint found in sea anemones

600-million-year-old body blueprint found in sea anemones

A new study from the University of Vienna reveals that sea anemones use a molecular mechanism known from bilaterian animals to form their back-to-belly body axis. This mechanism (“BMP shuttling”) enables cells to organize themselves during development by interpreting signaling gradients. The findings, published in Science Advances, suggest that this system evolved much earlier than […]
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