Biology

  1. Biology

Appendix Cancer Rates Quadruple Among Older Millennials, New Study Reveals

A groundbreaking new epidemiological study has unveiled an unexpected surge in the incidence of appendiceal adenocarcinoma (AA), a rare form of appendix cancer, in recent American birth cohorts. Employing robust population-based cancer registry data from the National Cancer Institute’s SEER (Surveillance, Epidemiology, and End Results) Program, researchers conducted a comprehensive birth cohort analysis spanning several […]
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  1. Biology

EGFR Stops α-Synuclein Clumps via DNAJB1

In a groundbreaking advance in the battle against Parkinson’s disease, researchers have unveiled a novel molecular pathway through which the epidermal growth factor receptor (EGFR) acts to mitigate one of the disease’s most destructive features: the aggregation of α-synuclein proteins in neuronal cells. This discovery shines new light on the intricate molecular dance that governs […]
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  1. Biology

Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity

Stereocilia are rod-like mechanosensory projections consisting of unidirectionally oriented actin filaments that extend into the inner ear hair cell cytoskeleton, forming dense rootlets. Taperin (TPRN) localizes to the narrowed-down base of stereocilia, where they pivot in response to sound and gravity. We show that TPRN–deficient mice have progressive deafness characterized by gradual asynchronous retraction and […]
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  1. Biology

Remote Detection of Dizziness and Balance Disorders: AI’s New Role in

Artificial intelligence (AI) continues to revolutionize various fields, and healthcare is no exception. This transformative technology is increasingly making significant inroads in medical diagnostics, particularly in the interpretation of complex medical images. This approach helps clinicians better assess disease severity, formulate treatment plans, and monitor patient progress over time. Despite the rapid advancements in AI, […]
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  1. Biology

Deep Learning Enhances Polygenic Score Accuracy

In recent years, the field of genomics has witnessed remarkable advancements driven by the integration of artificial intelligence, particularly deep learning, with traditional genetic analyses. Among the most promising applications is the enhancement of polygenic scores, which estimate an individual’s susceptibility to various diseases by aggregating the effects of numerous genetic variants. A groundbreaking study […]
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  1. Biology

Ecdysone regulates phagocytic cell fate of epithelial cells in developing Drosophila eggs

Acquisition of nonprofessional phagocytic cell fate plays an important role in sculpting functional metazoan organs and maintaining overall tissue homeostasis. Though physiologically highly relevant, how the normal epithelial cells acquire phagocytic fate is still mostly unclear. We have employed the Drosophila ovary model to demonstrate that the classical ecdysone signaling in the somatic epithelial follicle […]
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  1. Biology

Unlocking the Complete Power of Multiferroic Materials for Next-Generation

In a remarkable advancement for the realm of magnetic memory technologies, researchers at the Institute of Science Tokyo have unveiled a groundbreaking discovery regarding the behavior of multiferroic materials. Led by Assistant Professor Kei Shigematsu and Specially Appointed Associate Professor Hena Das, this innovative study challenges long-standing assumptions about the mechanisms of magnetization in such […]
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  1. Biology

Pex30-dependent membrane contact sites maintain ER lipid homeostasis

In eukaryotic cells, communication between organelles and the coordination of their activities depend on membrane contact sites (MCS). How MCS are regulated under the dynamic cellular environment remains poorly understood. Here, we investigate how Pex30, a membrane protein localized to the endoplasmic reticulum (ER), regulates multiple MCS in budding yeast. We show that Pex30 is […]
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  1. Biology

Advances in Radiotherapy for Advanced Lung Cancer

In a groundbreaking meta-analysis published in BMC Cancer, researchers have shed new light on the evolving radiotherapy paradigms for treating locally advanced non-small cell lung cancer (LA-NSCLC), emphasizing innovations that could dramatically alter clinical outcomes. The study meticulously compares high-dose-rate (HDR) brachytherapy, stereotactic body radiotherapy (SBRT), and hypofractionated proton therapy—three cutting-edge modalities within the domain […]
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Good Reads

EU Commissioner Várhelyi revives Biotech Act for 2025

EU Commissioner Várhelyi revives Biotech Act for 2025

In a panel discussion at Medicines for Europe Annual Conference, EU Health Commissioner Olivér Várhelyi made a surprise announcement that the Commission will adopt the EU Biotech Act by the end of this year, citing growing “global challenges”. According to the EU Commission’s work programme, the legislation was initially scheduled for adoption in Q3 2025, […]
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EU Commissioner Várhelyi revives Biotech Act for 2025

EU Commissioner Várhelyi revives Biotech Act for 2025

In a panel discussion at Medicines for Europe Annual Conference, EU Health Commissioner Olivér Várhelyi made a surprise announcement that the Commission will adopt the EU Biotech Act by the end of this year, citing growing “global challenges”. According to the EU Commission’s work programme, the legislation was initially scheduled for adoption in Q3 2025, […]
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