Biology

  1. Biology

Anillin links up with RhoA to break the symmetry of cytokinetic ring closure

During animal cell cytokinesis, active RhoA assembles actomyosin-based contractile rings that tend to close asymmetrically. Through imaging C. elegans zygotes, Lebedev et al. (https://doi.org/10.1083/jcb.202405182) reveal that the scaffold protein, anillin, promotes asymmetric ring closure by locally sequestering RhoA from its canonical effectors and thereby limiting actomyosin contractility.
Written by
  1. Biology

Extended Reality Boccia Demonstrates Promising Rehabilitation Benefits

In recent years, the integration of extended reality (XR) technologies into therapeutic and rehabilitation contexts has opened new horizons for enhancing physical and cognitive health, particularly in older adults. A pioneering research group from Osaka Metropolitan University has taken a bold step forward by developing an XR version of boccia, a precision ball sport traditionally […]
Written by
  1. Biology

CDK4/6 Inhibitors Boost First-Line Breast Cancer Therapy

In an ambitious stride toward optimizing treatment for hormone receptor-positive (HR+)/HER2-negative advanced breast cancer, a recent comprehensive network meta-analysis has brought fresh insights into the comparative efficacy and safety of the four widely used CDK4/6 inhibitors combined with aromatase inhibitors (AI). Published in the upcoming 2025 volume of BMC Cancer, this pioneering study meticulously synthesizes […]
Written by
  1. Biology

Rewrite Longitudinal profiling of low-abundance strains in microbiomes with

The ability to detect and quantify microbiota over time from shotgun metagenomic data has a plethora of clinical, basic science and public health applications. Given these applications, and the observation that pathogens and other taxa of interest can reside at low relative abundance, there is a critical need for algorithms that accurately profile low-abundance microbial […]
Written by
  1. Biology

MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids

KRAS, a small GTPase involved in cell proliferation and differentiation, frequently gains activating mutations in human cancers. For KRAS to function, it must bind the plasma membrane (PM) via interactions between its membrane anchor and phosphatidylserine (PtdSer). Therefore, depleting PM PtdSer abrogates KRAS PM binding and activity. From a genome-wide siRNA screen to identify genes […]
Written by
  1. Biology

Rising Anal Cancer Rates Most Pronounced Among Older White and Hispanic

In recent years, the landscape of anal cancer incidence in the United States has revealed surprising and concerning trends, with new research uncovering a notable rise among older women, particularly within white and Hispanic populations. This finding challenges longstanding assumptions about the demographics traditionally considered at highest risk for this rare but serious malignancy, prompting […]
Written by
  1. Biology

A cortical pool of LIN-5 (NuMA) controls cytokinetic furrow formation and cytokinesis completion

In animal cells, cleavage furrow formation is controlled by localized activation of the GTPase RhoA at the equatorial membrane using cues transmitted from the spindle. Here, we explore the function of LIN-5, a well-studied protein known for its role in aster separation and spindle positioning in cleavage furrow formation. We show that the cortical pool […]
Written by
  1. Biology

Lanthanide–Nickel Complexes with Ligand-Free Ni2− Anion

In a groundbreaking development at the crossroads of inorganic chemistry and materials science, researchers have unveiled a novel class of lanthanide–nickel molecular intermetallic complexes that push the boundaries of traditional transition metal chemistry. Central to this discovery is the stabilization of a notoriously elusive species: a ligand-free nickel anion bearing a formal negative oxidation state […]
Written by
  1. Biology

A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome

Basement membranes (BMs) are specialized extracellular matrix (ECM) structures essential for organ morphogenesis, architecture, and function. BM composition and properties vary between tissues, developmental stages, and disease states, and there is only a rudimentary understanding of BM dynamics. Here, we introduce a versatile mouse model carrying a multifunctional dual-color fluorescence tagged allele with knockout potential […]
Written by

Good Reads

Unlocking the Complete Power of Multiferroic Materials for Next-Generation

In a remarkable advancement for the realm of magnetic memory technologies, researchers at the Institute of Science Tokyo have unveiled a groundbreaking discovery regarding the behavior of multiferroic materials. Led by Assistant Professor Kei Shigematsu and Specially Appointed Associate Professor Hena Das, this innovative study challenges long-standing assumptions about the mechanisms of magnetization in such […]
Written by

Gen Z Leads the Call for Conservation With TreeTalks – State of the Planet

An old dense spruce forest in Holma, Sweden. Credit: W.carter, CC0, via Wikimedia Commons Last month, Amanda Biscoe and Pamela Treviño hosted TreeTalks, a film screening and panel discussion focused on rainforest conservation and the role of young people in shaping its future. Through their work as co-directors of Gen Z for the Trees, a […]
Written by

Worlwide

Unlocking the Complete Power of Multiferroic Materials for Next-Generation

In a remarkable advancement for the realm of magnetic memory technologies, researchers at the Institute of Science Tokyo have unveiled a groundbreaking discovery regarding the behavior of multiferroic materials. Led by Assistant Professor Kei Shigematsu and Specially Appointed Associate Professor Hena Das, this innovative study challenges long-standing assumptions about the mechanisms of magnetization in such […]
Written by

Gen Z Leads the Call for Conservation With TreeTalks – State of the Planet

An old dense spruce forest in Holma, Sweden. Credit: W.carter, CC0, via Wikimedia Commons Last month, Amanda Biscoe and Pamela Treviño hosted TreeTalks, a film screening and panel discussion focused on rainforest conservation and the role of young people in shaping its future. Through their work as co-directors of Gen Z for the Trees, a […]
Written by
Scientists uncover new way viruses fight back against bacteria

Leprosy existed in America long before arrival of Europeans

Long considered a disease brought to the Americas by European colonizers, leprosy may actually have a much older history on the American continent. Scientists from the Institut Pasteur, the CNRS, and the University of Colorado (USA), in collaboration with various institutions in America and Europe, reveal that a recently identified second species of bacteria responsible […]
Written by

Trending

Login

Welcome to Life Science News!
"Explore the Latest Discoveries and Breakthroughs in Life Science with Life Science News!"
Read Smart, Save Time
Pick all the topics you are interested in to fill your homepage with stories you'll love.
Join our community
Registration is closed.