Biology

  1. Biology

Body-Resonance Enables High-Speed Wearable Wireless Links

In a remarkable leap forward for wearable technology and wireless communication, researchers have introduced a groundbreaking concept known as “body-resonance” that may revolutionize how wearable devices communicate at high speeds. Published in the prestigious journal Communications Engineering, this novel mechanism leverages the human body as a transmission medium, functioning akin to a sophisticated transmission line. […]
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  1. Biology

Exploring Uveitis: Proteomics of Eye Fluids

In the rapidly advancing field of ocular research, the analysis of aqueous and vitreous humor has emerged as a crucial area of study, particularly in understanding the complex mechanisms underlying uveitis. Uveitis, an inflammatory condition affecting the uveal tract of the eye, remains a significant cause of visual impairment worldwide. Recent insights from proteomics analysis […]
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  1. Biology

Perinuclear non-centrosomal microtubules direct nuclei dispersion during epithelial morphogenesis

As cells contract and reshape to enable tissue morphogenesis, their own internal structures can constrain these behaviors. In the Drosophila germband, the uncrowding of nuclei away from an initially common plane is required for efficient cell intercalation and extension. Here, we find that a centrosomally derived microtubule network transitions into non-centrosomal arrays that are deeply […]
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  1. Biology

Targeting Aerobic Glycolysis to Combat Bladder Cancer Resistance

Research in the field of cancer biology has consistently revealed critical insights into the mechanisms underpinning tumor progression and drug resistance. Recent studies have illuminated the role of aerobic glycolysis, a process where cancer cells preferentially convert glucose to lactate, in the development of drug resistance in various malignancies. A groundbreaking investigation conducted by Weng, […]
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  1. Biology

Independent nuclear and organellar mechanisms determine apicoplast fate in malaria parasites

The apicoplast organelle of the malaria parasite, Plasmodium falciparum, is essential for parasite replication, though its cell cycle regulation remains poorly understood. We developed a dynamic live-imaging platform with analytical capabilities to track subcellular structures throughout the parasite’s 48-h intraerythrocytic life cycle. Our analysis revealed four distinct morphological stages in apicoplast development that correlate with […]
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  1. Biology

Transparent Solar Cells with UV-Blocking Fluorene Dyes

Recent advancements in solar cell technology have opened up new frontiers in the pursuit of sustainable and efficient energy solutions. One of the most compelling developments in this realm is the emergence of highly transparent dye-sensitized solar cells (DSSCs). Researchers have been delving into the intricacies of these solar cells that not only promise greater […]
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  1. Biology

Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Receptor tyrosine kinases (RTKs) are important cargo in endocytic trafficking, yet their role in endosomal sorting and maturation of multivesicular bodies remains unclear. Here, we show that the ErbB3 (HER3) receptor sorts internalized Integrin β1 and the transferrin receptor, for endocytic recycling, in a manner that does not require ligand-induced ErbB3 signaling in breast epithelial […]
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  1. Biology

Boosting Cancer Immunotherapy by Targeting DNA Repair

In the relentless pursuit of more effective cancer treatments, a burgeoning field of research has been focusing on an intricate cellular process known as the DNA damage response (DDR). Recent advances have illuminated how manipulating DDR pathways can substantially enhance the effectiveness of cancer immunotherapy, a revolutionary treatment modality that harnesses the body’s immune system […]
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  1. Biology

High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation

Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […]
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Good Reads

The poison frog that fooled scientists for decades

The poison frog that fooled scientists for decades

Scientists at the University of Kansas Biodiversity Institute and Natural History Museum recently uncovered a mistake that dates back decades involving a poison frog specimen from Peru. The frog had been incorrectly identified and designated as a holotype, which is the single preserved specimen used to officially define a species. While modern taxonomy may also […]
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The poison frog that fooled scientists for decades

The poison frog that fooled scientists for decades

Scientists at the University of Kansas Biodiversity Institute and Natural History Museum recently uncovered a mistake that dates back decades involving a poison frog specimen from Peru. The frog had been incorrectly identified and designated as a holotype, which is the single preserved specimen used to officially define a species. While modern taxonomy may also […]
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The traffic controller: GARLH4 dictates neuroligin synapse-type preference

Neuroligin isoforms are commonly thought to intrinsically specify synapse identity. In this issue, Yamasaki et al. (https://doi.org/10.1083/jcb.202507190) show that the auxiliary protein GARLH4 (LHFPL4) instead dictates neuroligin preference via competitive hierarchy, enabling dynamic reassignment between excitatory and inhibitory postsynaptic domains.
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