Biology

  1. Biology

LLP1 is a pyrophosphatase involved in homeostasis/quality control of dolichol-linked oligosaccharide

Dolichol-linked oligosaccharide (DLO) is the precursor for asparagine (N)-linked protein glycosylation. DLO synthesis can be impaired by genetic and environmental factors, leading to the accumulation of various immature DLO intermediates that are subsequently cleaved into phosphorylated oligosaccharides (POSs). Despite the fact that its activity has been known since the 1970s, the identity of the enzyme […]
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  1. Biology

Genomic Study Uncovers Resilience of Coral-Killing Sponge

In the vast and intricate ecosystems of coral reefs, a hidden danger lurks, posing threats not just to the colorful corals themselves but to entire marine environments. Recent research spearheaded by Liu, PY., Chiu, WC., Lim, S.L., and their collaborators has shed light on the mysterious and pervasive sponge known as Terpios hoshinota. This sponge, […]
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  1. Biology

Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging

Clathrin-mediated endocytosis (CME) is a critical cellular process that regulates nutrient uptake, membrane composition, and signaling. Although replicative aging affects many cellular functions, its impact on CME remains largely unknown. We show that in budding yeast, older cells have slower assembly of early and coat CME modules, resulting in longer endocytic turnover and reduced Mup1 […]
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  1. Biology

Genome-wide Study Links REM Sleep Disorder, Parkinson’s

In a groundbreaking genetic study published in the latest issue of npj Parkinson’s Disease, researchers have unveiled new insights into the complex relationship between REM sleep behavior disorder (RBD) and Parkinson’s disease (PD). This seminal work, conducted through a comprehensive genome-wide association study (GWAS), elucidates critical genetic underpinnings that could redefine our understanding of the […]
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  1. Biology

Key Drivers of Corporate Governance in Burundi’s Cooperatives

Corporate governance has become a widely discussed topic across various sectors, demonstrating a significant impact on organizational effectiveness and operational transparency. In recent years, the agricultural sector, particularly cooperatives, has not been an exception to these discussions. A notable study conducted by researchers Nasangwe, Okello, and Gathungu delves into the nuances of corporate governance practices […]
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  1. Biology

Lung Ultrasound and Heart Index Predict Preterm Infant Outcomes

In a pioneering exploration into neonatal respiratory care, researchers have probed the intricate relationship between lung ultrasound imaging and cardiac function in preterm infants grappling with respiratory failure. This cutting-edge investigation opens a promising window into how bedside ultrasound metrics might serve as vital indicators of cardiopulmonary interactions, potentially revolutionizing clinical monitoring and therapeutic strategies […]
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  1. Biology

The purification of biomolecular condensates: Bottlenecks and strategies

Biomolecular condensates are large assemblies of proteins and nucleic acids that form distinct compartments inside the cell without being surrounded by a membrane. They form through multivalent interactions, are not stereospecifically defined, and can scale with component addition. By concentrating specific biomolecules at specific times and cellular locations, condensates play key roles in many processes, […]
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  1. Biology

Impact of Electrode Material on Radish Germination

In a groundbreaking study that sheds light on the intersection of plasma physics and agricultural science, researchers Kawano et al. have delved deep into the unique effects of discharge electrode materials on the germination of radish sprouts when utilizing cavitation bubble plasma-treated water. This cutting-edge research, published in the journal Discover Plants, addresses an intriguing […]
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