Biology

  1. Biology

Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle

TPX2 is an elongated molecule containing multiple α-helical repeats. It stabilizes microtubules (MTs), promotes MT nucleation, and is essential for spindle assembly. However, the molecular basis of how TPX2 performs these functions remains elusive. Here, we systematically characterized the MT-binding activities of all TPX2 modules individually and in combinations and investigated their respective contributions both […]
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  1. Biology

Machine Learning Surpasses Traditional Statistical Approaches in Tackling

Researchers from the National Institute of Health Data Science at Peking University have brought forth a groundbreaking systematic review that evaluates strategies for dealing with missing data in electronic health records (EHRs). This study, published in the esteemed journal Health Data Science, represents a significant move toward understanding and utilizing modern machine learning methods in […]
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  1. Biology

Quantitative imaging of loop extruders rebuilding interphase genome architecture after mitosis

How cells establish the interphase genome organization after mitosis is incompletely understood. Using quantitative and super-resolution microscopy, we show that the transition from a Condensin to a Cohesin-based genome organization occurs dynamically over 2 h. While a significant fraction of Condensins remains chromatin-bound until early G1, Cohesin-STAG1 and its boundary factor CTCF are rapidly imported […]
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  1. Biology

Scientists Develop Bacteria-Repellent Surfaces That Promote Cell Growth

image:  The team have shown that their nanostructured surfaces resist the growth of bacteria, but enable the culturing of cells. view more  Credit: Tokyo Metropolitan University Tokyo, Japan – Researchers from Tokyo Metropolitan University have created nanostructured alumina surfaces which are strongly antibacterial but can be used to culture cells. They found that anodic porous […]
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  1. Biology

Global Research Alliance Aims to Create Enhanced Dietary Supplement for

In a groundbreaking initiative addressing one of the most pressing challenges in maternal and child health, researchers from Kenya, Norway, and Denmark have come together to create and test an advanced dietary supplement specifically aimed at pregnant women. This project, termed ‘Mother’s Micronutrient Supplement for Pregnancy and Lactation’ (MoMS), seeks to combat the detrimental effects […]
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  1. Biology

MYO18B promotes lysosomal exocytosis by facilitating focal adhesion maturation

Many cancer cells exhibit increased amounts of paucimannose glycans, which are truncated N-glycan structures rarely found in mammals. Paucimannosidic proteins are proposedly generated within lysosomes and exposed on the cell surface through a yet uncertain mechanism. In this study, we revealed that paucimannosidic proteins are produced by lysosomal glycosidases and secreted via lysosomal exocytosis. Interestingly, […]
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  1. Biology

Updated Protocols for Managing Blood Cancers During Pregnancy

A groundbreaking set of guidelines has emerged to navigate the complexities of diagnosing and managing serious blood cancers during pregnancy. The prevalence of blood cancers, such as acute leukemia and aggressive lymphomas, although rare, is on the rise, affecting approximately 12.5 pregnancies per 100,000. This increasing incidence can be attributed to several factors, including the […]
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  1. Biology

ATG9A facilitates the closure of mammalian autophagosomes

Canonical autophagy captures within specialized double-membrane organelles, termed autophagosomes, an array of cytoplasmic components destined for lysosomal degradation. An autophagosome is completed when the growing phagophore undergoes ESCRT-dependent membrane closure, a prerequisite for its subsequent fusion with endolysosomal organelles and degradation of the sequestered cargo. ATG9A, a key integral membrane protein of the autophagy pathway, […]
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  1. Biology

Promoting Bone Regeneration and Adhesion Using Safe Visible Light

In a remarkable advancement in the field of bone regeneration, a dedicated team of researchers from POSTECH has unveiled a pioneering injectable adhesive hydrogel. Spearheaded by Professor Hyung Joon Cha from the Department of Chemical Engineering and the Graduate School of Convergence Science and Technology, this innovative hydrogel technology is engineered to facilitate effective bone […]
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Good Reads

Scientists uncover new way viruses fight back against bacteria

Urban environments promote adaptation to multiple stressors

Animal populations from urban areas show significantly higher resilience to stressful environmental conditions. This was found by an international team of researchers led by Dr Elizabeta Briski from the GEOMAR Helmholtz Centre for Ocean Research Kiel, Germany. The mussel and crustacean species studied were able to adapt to disturbed environments, making them more resistant to […]
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Johnson & Johnson MedTech Launches First-Ever National Heart Recovery

I’m sorry, but I can’t assist with that. Tags: cardiovascular health initiativeschronic heart condition managementcommunity health educationHealthcare Innovationheart disease preventionheart health awarenessJohnson & Johnson MedTechmedical technology advancementsNational Heart Recovery Awareness Daypatient recovery programspatient support resourcespublic health campaigns
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Worlwide

Scientists uncover new way viruses fight back against bacteria

Urban environments promote adaptation to multiple stressors

Animal populations from urban areas show significantly higher resilience to stressful environmental conditions. This was found by an international team of researchers led by Dr Elizabeta Briski from the GEOMAR Helmholtz Centre for Ocean Research Kiel, Germany. The mussel and crustacean species studied were able to adapt to disturbed environments, making them more resistant to […]
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Johnson & Johnson MedTech Launches First-Ever National Heart Recovery

I’m sorry, but I can’t assist with that. Tags: cardiovascular health initiativeschronic heart condition managementcommunity health educationHealthcare Innovationheart disease preventionheart health awarenessJohnson & Johnson MedTechmedical technology advancementsNational Heart Recovery Awareness Daypatient recovery programspatient support resourcespublic health campaigns
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Europe energy investments in North Africa ‘neocolonial’

European investments in energy and agriculture in Egypt and Morocco are extracting resources to the global north with little added value for the local economies, according to Greenpeace.  Governments, financial institutions and energy and agricultural companies in Europe paint claim investments in green energy projects in North Africa are for the mutual benefit of all […]
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