Biology

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Blueprint Reveals Pathway for Expanding Australia’s Bioeconomy

Australia stands at the precipice of a major economic transformation, brought to light by a newly released report from Queensland University of Technology (QUT). This thorough investigation emphasizes the urgency for Australia to develop a cohesive national bioeconomy strategy that could harness its rich biological resources. The authors of the report—researchers Madeline Smith, Dr. Jerome […]
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Visualizing nuclear pore complex plasticity with pan-expansion microscopy

The exploration of cell-type and environmentally responsive nuclear pore complex (NPC) plasticity requires new, accessible tools. Using pan-expansion microscopy (pan-ExM), NPCs were identified by machine learning–facilitated segmentation. They exhibited a large range of diameters with a bias for dilated NPCs at the basal nuclear surface in clusters suggestive of local islands of nuclear envelope tension. […]
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Rewrite Repurposing the memory-promoting meclofenoxate hydrochloride as a

Zhang, H., Fan, C., Li, L. et al. Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis.npj Parkinsons Dis. 11, 167 (2025). bu içeriği en az 2500 kelime olacak şekilde ve alt başlıklar ve madde içermiyecek şekilde ünlü bir science magazine için İngilizce olarak yeniden yaz. Teknik açıklamalar içersin […]
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Appendix Cancer Rates Quadruple Among Older Millennials, New Study Reveals

A groundbreaking new epidemiological study has unveiled an unexpected surge in the incidence of appendiceal adenocarcinoma (AA), a rare form of appendix cancer, in recent American birth cohorts. Employing robust population-based cancer registry data from the National Cancer Institute’s SEER (Surveillance, Epidemiology, and End Results) Program, researchers conducted a comprehensive birth cohort analysis spanning several […]
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EGFR Stops α-Synuclein Clumps via DNAJB1

In a groundbreaking advance in the battle against Parkinson’s disease, researchers have unveiled a novel molecular pathway through which the epidermal growth factor receptor (EGFR) acts to mitigate one of the disease’s most destructive features: the aggregation of α-synuclein proteins in neuronal cells. This discovery shines new light on the intricate molecular dance that governs […]
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Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity

Stereocilia are rod-like mechanosensory projections consisting of unidirectionally oriented actin filaments that extend into the inner ear hair cell cytoskeleton, forming dense rootlets. Taperin (TPRN) localizes to the narrowed-down base of stereocilia, where they pivot in response to sound and gravity. We show that TPRN–deficient mice have progressive deafness characterized by gradual asynchronous retraction and […]
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Remote Detection of Dizziness and Balance Disorders: AI’s New Role in

Artificial intelligence (AI) continues to revolutionize various fields, and healthcare is no exception. This transformative technology is increasingly making significant inroads in medical diagnostics, particularly in the interpretation of complex medical images. This approach helps clinicians better assess disease severity, formulate treatment plans, and monitor patient progress over time. Despite the rapid advancements in AI, […]
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Deep Learning Enhances Polygenic Score Accuracy

In recent years, the field of genomics has witnessed remarkable advancements driven by the integration of artificial intelligence, particularly deep learning, with traditional genetic analyses. Among the most promising applications is the enhancement of polygenic scores, which estimate an individual’s susceptibility to various diseases by aggregating the effects of numerous genetic variants. A groundbreaking study […]
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Ecdysone regulates phagocytic cell fate of epithelial cells in developing Drosophila eggs

Acquisition of nonprofessional phagocytic cell fate plays an important role in sculpting functional metazoan organs and maintaining overall tissue homeostasis. Though physiologically highly relevant, how the normal epithelial cells acquire phagocytic fate is still mostly unclear. We have employed the Drosophila ovary model to demonstrate that the classical ecdysone signaling in the somatic epithelial follicle […]
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