Biology Genome-wide Study Links REM Sleep Disorder, Parkinson’s In a groundbreaking genetic study published in the latest issue of npj Parkinson’s Disease, researchers have unveiled new insights into the complex relationship between REM sleep behavior disorder (RBD) and Parkinson’s disease (PD). This seminal work, conducted through a comprehensive genome-wide association study (GWAS), elucidates critical genetic underpinnings that could redefine our understanding of the […] Written by Bioengineer September 25, 2025September 25, 2025 Saving Bookmark this article Bookmarked
Biology How do trypanosome IFT trains choose special tracks? Intraflagellar transport trains in Trypanosoma brucei are known to selectively associate with a subset of axonemal doublet microtubules. In this issue, Araujo Alves et al. (https://doi.org/10.1083/jcb.202501088) aim to elucidate the mechanisms underlying this selective association using high-resolution microscopy approaches. Written by Admin September 23, 2025September 23, 2025 Saving Bookmark this article Bookmarked
Biology Key Drivers of Corporate Governance in Burundi’s Cooperatives Corporate governance has become a widely discussed topic across various sectors, demonstrating a significant impact on organizational effectiveness and operational transparency. In recent years, the agricultural sector, particularly cooperatives, has not been an exception to these discussions. A notable study conducted by researchers Nasangwe, Okello, and Gathungu delves into the nuances of corporate governance practices […] Written by Bioengineer September 21, 2025September 21, 2025 Saving Bookmark this article Bookmarked
Biology ATG16L strikes again! New findings link lysosome stress and physiology Lysosome stress responses are emerging, but their connections to normal physiology are not well understood. In this issue, Duque et al. (https://doi.org/10.1083/jcb.202503166) discover that the autophagy protein ATG16L, a mediator of a stress response called CASM, also regulates normal lysosome function. Written by Admin September 20, 2025September 20, 2025 Saving Bookmark this article Bookmarked
Biology Lung Ultrasound and Heart Index Predict Preterm Infant Outcomes In a pioneering exploration into neonatal respiratory care, researchers have probed the intricate relationship between lung ultrasound imaging and cardiac function in preterm infants grappling with respiratory failure. This cutting-edge investigation opens a promising window into how bedside ultrasound metrics might serve as vital indicators of cardiopulmonary interactions, potentially revolutionizing clinical monitoring and therapeutic strategies […] Written by Bioengineer September 18, 2025September 18, 2025 Saving Bookmark this article Bookmarked
Biology The purification of biomolecular condensates: Bottlenecks and strategies Biomolecular condensates are large assemblies of proteins and nucleic acids that form distinct compartments inside the cell without being surrounded by a membrane. They form through multivalent interactions, are not stereospecifically defined, and can scale with component addition. By concentrating specific biomolecules at specific times and cellular locations, condensates play key roles in many processes, […] Written by Admin September 16, 2025September 16, 2025 Saving Bookmark this article Bookmarked
Biology Impact of Electrode Material on Radish Germination In a groundbreaking study that sheds light on the intersection of plasma physics and agricultural science, researchers Kawano et al. have delved deep into the unique effects of discharge electrode materials on the germination of radish sprouts when utilizing cavitation bubble plasma-treated water. This cutting-edge research, published in the journal Discover Plants, addresses an intriguing […] Written by Bioengineer September 14, 2025September 14, 2025 Saving Bookmark this article Bookmarked
Biology Lipid droplets: Open questions and conceptual advances around a unique organelle Once viewed as mere lipid inclusions, the past four decades have witnessed an explosion of research into lipid droplet (LD) biogenesis and function. Pioneering cell biology, biochemical, genetics, and lipidomic studies now reveal LDs as active players in lipid metabolism and cellular homeostasis. Here, we discuss some of the major findings that defined LDs as bona […] Written by Admin September 13, 2025September 13, 2025 Saving Bookmark this article Bookmarked
Biology ABCA7 Variants Alter Neuronal Mitochondria, Phosphatidylcholine In the quest to unravel the intricate ways by which genetic variations influence brain function and neurodegenerative disease, a groundbreaking study has illuminated the pivotal role of the ABCA7 gene in regulating mitochondrial health within neurons. Leveraging cutting-edge genomic and bioenergetic analyses, researchers have unveiled that loss-of-function (LoF) mutations in ABCA7 lead to profound alterations […] Written by Bioengineer September 11, 2025September 11, 2025 Saving Bookmark this article Bookmarked
Biology SEPTIN9 locally activates the RhoGEF ARHGEF18 to promote early stages of mitochondrial fission Mitochondria continually undergo fission to maintain their network and health. Nascent fission sites are marked by the ER, which facilitates actin polymerization to drive calcium flux into the mitochondrion and constrict the inner mitochondrial membrane. Septins are a major eukaryotic cytoskeleton component that forms filaments that can both directly and indirectly modulate other cytoskeleton components, […] Written by Admin September 9, 2025September 9, 2025 Saving Bookmark this article Bookmarked
Can Mayor Mamdani Turn Climate Action Into an Affordability Win for NYC? – State of the Planet Below-average temperatures and gusty winds did not deter tens of thousands of people from gathering in lower Manhattan last week to witness Zohran Mamdani take an oath to become New York City’s next mayor. Mayor Zohran Mamdani. Credit: Karamccurdy via Wikimedia Commons “Beginning today, we will govern expansively and audaciously,” Mamdani said during his inauguration speech. “We may not always succeed, but never will we be accused of lacking […] Written by Guest January 11, 2026January 11, 2026 Saving Bookmark this article Bookmarked
The biggest biotech funding rounds in December 2025 The companies Kymera Therapeutics, Immunovant, and Dyne Therapeutics bagged the biggest biotech funding rounds overall in December 2025 across private and public funding types. In this article, we break down last month’s private and public fundraising activity, looking at the largest rounds in more detail. Private biotech funding rounds in December 2025 First, let’s take […] Written by Willow Shah-Neville January 10, 2026January 10, 2026 Saving Bookmark this article Bookmarked
Can Mayor Mamdani Turn Climate Action Into an Affordability Win for NYC? – State of the Planet Below-average temperatures and gusty winds did not deter tens of thousands of people from gathering in lower Manhattan last week to witness Zohran Mamdani take an oath to become New York City’s next mayor. Mayor Zohran Mamdani. Credit: Karamccurdy via Wikimedia Commons “Beginning today, we will govern expansively and audaciously,” Mamdani said during his inauguration speech. “We may not always succeed, but never will we be accused of lacking […] Written by Guest January 11, 2026January 11, 2026 Saving Bookmark this article Bookmarked
The biggest biotech funding rounds in December 2025 The companies Kymera Therapeutics, Immunovant, and Dyne Therapeutics bagged the biggest biotech funding rounds overall in December 2025 across private and public funding types. In this article, we break down last month’s private and public fundraising activity, looking at the largest rounds in more detail. Private biotech funding rounds in December 2025 First, let’s take […] Written by Willow Shah-Neville January 10, 2026January 10, 2026 Saving Bookmark this article Bookmarked
The 4x rule: Why some people’s DNA is more unstable than others A large scale genetic analysis of more than 900,000 people has revealed that specific regions of DNA become increasingly unstable over time. These regions are made up of very short sequences that repeat again and again, and the study shows that they tend to grow longer as people age. Researchers also found that common inherited […] Written by Admin January 10, 2026January 10, 2026 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked