Biology

  1. Biology

Pilot Intervention to Support Caregivers of Schizophrenic Seniors

Recent research has highlighted a critical but frequently overlooked aspect of mental health care—the impact on family caregivers of older adults diagnosed with schizophrenia. The emotional, psychological, and physical toll on these caregivers can be substantial, as they navigate the complex dynamics of caring for loved ones with mental health issues. A study conducted by […]
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  1. Biology

Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity

ch-TOG family proteins, including the budding yeast Stu2, are essential for spindle formation and chromosome segregation. Such functions depend on an array of activities ranging from microtubule nucleation, polymerization, and depolymerization to conferring tension sensitivity to kinetochores. This functional diversity makes it challenging to dissect these various functions and understand their relative importance. Here, we […]
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  1. Biology

Circuit Links Drive and Social Contact to Mate

Neural circuits orchestrate complex behaviors by integrating diverse internal states with external environmental cues. A groundbreaking study published in Nature in 2025 by Salay, Tsao, and Anderson illuminates a previously obscure neural pathway that governs mating behavior in male mice by combining sexual drive with direct social contact, revealing the delicate neurobiological choreography underlying reproductive […]
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  1. Biology

Allocation of resources among multiple daughter cells

Cell division commonly produces two daughter cells, but there are many exceptions where large cells produce multiple daughters. Multiple fission of some green algae and bacteria; cellularization during embryogenesis of plants and insects; and growth of Ichthyosporeans, Chytrids, and Apicomplexans all provide variations on this theme. In some yeast species, a large multinucleate mother cell […]
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  1. Biology

Nomograms Enhance Prognosis in ECMO for Septic Shock

In a groundbreaking study, researchers are advancing the field of critical care medicine with the introduction of innovative nomograms designed to predict outcomes for patients undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) treatment for septic shock. Septic shock remains one of the most severe complications of infections, often leading to multiple organ failure and significant mortality […]
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  1. Biology

Submembrane liprin-α1 clusters spatially localize insulin granule fusion

Insulin granule fusion in pancreatic β cells localizes to where they contact the ECM of the islet capillaries. The mechanism(s) underpinning localization are unclear. Using glucose or high K+ stimulation or the global uncaging of Ca2+, we show granule fusion consistently focused to the β cell–ECM interface, suggesting a specific localization mechanism. We tested for […]
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  1. Biology

Craving, Relapse, and Childhood Trauma: A Network Study

In recent years, the global consciousness regarding drug addiction and relapse has expanded considerably, spotlighting the intricate psychological and environmental factors that shape these phenomena. A groundbreaking study published in the International Journal of Mental Health and Addiction by Zhuang, Song, Jin, and colleagues offers a nuanced exploration into the complex interplay between craving, relapse, […]
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  1. Biology

Aortic Valve Guides Umbilical Artery Catheter Placement

In the fast-evolving world of neonatal intensive care, the quest for safer, more efficient methods to monitor and treat our most fragile patients is relentless. A new study published in the Journal of Perinatology sheds light on a novel ultrasound-guided technique that may revolutionize the placement of umbilical artery catheters (UAC) in neonates. This method […]
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  1. Biology

Triglyceride-Glucose and Waist Circumference: Diabetes Risk Insights

In the rapidly evolving landscape of diabetes research, recent findings shed light on the intricate interplay between various metabolic indicators and their influence on diabetes risk. One of the most compelling studies highlighting these interactions comes from a national cohort investigation led by Shan, Liu, and Gao. This pioneering research delves into the significance of […]
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  1. Biology

Identification of organelle-specific autophagy regulators from tandem CRISPR screens

Autophagy is a conserved degradative process that promotes cellular homeostasis under stress conditions. Under nutrient starvation, autophagy is nonselective, promoting indiscriminate breakdown of cytosolic components. Conversely, selective autophagy is responsible for the specific turnover of damaged organelles. We hypothesized that selective autophagy may be regulated by signaling pathways distinct from those controlling starvation-induced autophagy, thereby […]
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Good Reads

Can Mayor Mamdani Turn Climate Action Into an Affordability Win for NYC?  – State of the Planet

Below-average temperatures and gusty winds did not deter tens of thousands of people from gathering in lower Manhattan last week to witness Zohran Mamdani take an oath to become New York City’s next mayor.  Mayor Zohran Mamdani. Credit: Karamccurdy via Wikimedia Commons “Beginning today, we will govern expansively and audaciously,” Mamdani said during his inauguration speech. “We may not always succeed, but never will we be accused of lacking […]
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The biggest biotech funding rounds in November 2025

The biggest biotech funding rounds in December 2025

The companies Kymera Therapeutics, Immunovant, and Dyne Therapeutics bagged the biggest biotech funding rounds overall in December 2025 across private and public funding types. In this article, we break down last month’s private and public fundraising activity, looking at the largest rounds in more detail. Private biotech funding rounds in December 2025 First, let’s take […]
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Worlwide

Can Mayor Mamdani Turn Climate Action Into an Affordability Win for NYC?  – State of the Planet

Below-average temperatures and gusty winds did not deter tens of thousands of people from gathering in lower Manhattan last week to witness Zohran Mamdani take an oath to become New York City’s next mayor.  Mayor Zohran Mamdani. Credit: Karamccurdy via Wikimedia Commons “Beginning today, we will govern expansively and audaciously,” Mamdani said during his inauguration speech. “We may not always succeed, but never will we be accused of lacking […]
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The biggest biotech funding rounds in November 2025

The biggest biotech funding rounds in December 2025

The companies Kymera Therapeutics, Immunovant, and Dyne Therapeutics bagged the biggest biotech funding rounds overall in December 2025 across private and public funding types. In this article, we break down last month’s private and public fundraising activity, looking at the largest rounds in more detail. Private biotech funding rounds in December 2025 First, let’s take […]
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