Pharmaceuticals and Drug Development

  1. Pharmaceuticals and Drug Development

Applied Therapeutics Receives Complete Response Letter from U.S. FDA Regarding New Drug Application for Govorestat for Classic Galactosemia

NEW YORK, Nov. 27, 2024 (GLOBE NEWSWIRE) — Applied Therapeutics, Inc. (Nasdaq: APLT), a biopharmaceutical company dedicated to creating transformative treatments for rare disease, today announced that the U.S. Food and Drug Administration (FDA) has…
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  1. Pharmaceuticals and Drug Development

VU Researchers Publish Study on the Mechanism of CRISPR-Cas “Protein Scissors” in Molecular Cell

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, also known as DNA or gene ‘scissors’, which have revolutionized the field of genome editing, enabling scientists to […]
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  1. Pharmaceuticals and Drug Development

Pioneer Group’s life sciences campuses host biggest Ada Lovelace Day event to date

The event was the seventh annual Ada Lovelace Day celebration run by Pioneer in collaboration with educational charity Ignite! and the biggest to date. The two-day event showcased the real-world impact of women in science through interactive workshops held at MediCity Nottingham, Kent Science Park, Wilton Centre, Hexagon Tower, BioCity Glasgow, BioCity Nottingham, Edinburgh Technopole, […]
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  1. Pharmaceuticals and Drug Development

Stealth BioTherapeutics Announces Positive Vote from FDA Advisory Committee Meeting Supporting Potential Approval of Elamipretide for the Treatment of Barth Syndrome

NEEDHAM, Mass., Oct. 11, 2024 /PRNewswire/ — Stealth BioTherapeutics Inc. (the “Company” or “Stealth”), a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel…
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Good Reads

Hornet-eating frog shows remarkable venom resistance

Hornet-eating frog shows remarkable venom resistance

A frog with an unexpectedly strong resistance to venom has been identified, and it routinely eats hornets despite the insects’ dangerous stingers. Researchers believe this species may become a useful model organism for exploring how animals develop tolerance to venom. For many people, even glimpsing a hornet’s stinger is enough to cause alarm. Yet certain […]
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High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation

Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […]
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Worlwide

Hornet-eating frog shows remarkable venom resistance

Hornet-eating frog shows remarkable venom resistance

A frog with an unexpectedly strong resistance to venom has been identified, and it routinely eats hornets despite the insects’ dangerous stingers. Researchers believe this species may become a useful model organism for exploring how animals develop tolerance to venom. For many people, even glimpsing a hornet’s stinger is enough to cause alarm. Yet certain […]
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High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation

Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […]
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The hidden harm from salmon farming

In addition to parasites, pathogens, chemical residues, and other treatments can persist in cages. Fallow sites are expected to undergo complete removal of fish and nets to limit pathogen carryover. Campaigners, however, say the Aird site “continued functioning as a reservoir of disease and flesh-eating lice.” Read: The catch. Unsustainable Abigail Penny, executive director of […]
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