1. Biology

Dispersion-Engineered Metasurfaces: Debye Relaxation Unveiled

In the rapidly advancing domain of photonics and metamaterials, researchers continually seek novel pathways to manipulate light with precision and efficiency unachievable by conventional means. A groundbreaking study published in Light: Science & Applications by Ahmed, Qi, and Chen heralds a significant leap forward in our understanding and engineering of metasurfaces, focusing on the integration […]
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  1. Environmental Science

In Norway, Climate Goals Clash With Indigenous Herders’ Rights – State of the Planet

A recent climate initiative by the Norwegian government is facing opposition from the Saami Indigenous people, whose territories are directly affected. The proposed 54-kilometer power line would be built by the state-owned energy company Equinor in the northernmost portion of the country, well above the Arctic Circle. The Saami believe their rights to cultural preservation […]
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From cursed tomb fungus to cancer cure: Aspergillus flavus yields potent new drug
  1. Life Sciences

From cursed tomb fungus to cancer cure: Aspergillus flavus yields potent new drug

Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient tombs, the researchers modified the chemicals and tested them against leukemia cells. The result? A promising cancer-killing compound that rivals FDA-approved […]
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  1. Pharmaceuticals and Drug Development

UK antibiotic subscription model key to supporting antibiotic investment

For the world to meet the health challenge posed by increasing antimicrobial resistance (AMR), new ways must be found to overcome the market failure that holds back the development of new antibiotics.  Critical to this is greater understanding of the factors needed to persuade investors to support research and development (R&D) efforts. The latest report […]
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Frozen in time: Transparent worms keep genes in sync for 20 million years
  1. Life Sciences

Frozen in time: Transparent worms keep genes in sync for 20 million years

Two species of worms have retained remarkably similar patterns in the way they switch their genes on and off despite having split from a common ancestor 20 million years ago, a new study finds. The findings appear in the June 19 issue of the journal Science. “It was just remarkable, with this evolutionary distance, that […]
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  1. Biology

ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the Fanconi anemia pathway

The Fanconi anemia (FA) DNA repair pathway is required for the repair of DNA interstrand cross-links (ICLs). ICLs are caused by genotoxins, such as chemotherapeutic agents or reactive aldehydes. Inappropriately repaired ICLs contribute to hematopoietic stem cell (HSC) failure and tumorigenesis. While endogenous acetaldehyde and formaldehyde are known to induce HSC failure and leukemia in […]
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  1. Environmental Science

After the ‘Last Generation’

Soul-searching Second, the idea that repression of the movement would act as a ‘backfiring tool’, stirring public sympathy proved overly optimistic. “If they lock us up, there will be an outcry,” some activists claimed. Repression and court cases did not trigger mass support. Instead, the crackdowns dampened the movement’s momentum. Third, the rise of the […]
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Monster salamander with powerful jaws unearthed in Tennessee fossil find
  1. Life Sciences

Monster salamander with powerful jaws unearthed in Tennessee fossil find

A giant, strong-jawed salamander once tunneled through ancient Tennessee soil. And thanks to a fossil unearthed near East Tennessee State University, scientists now better understand how it helped shape Appalachian amphibian diversity. The giant plethodontid salamander now joins the remarkable roster of fossils from the Gray Fossil Site & Museum. The findings appeared in the […]
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AI Diagnoses Vocal Cord Paralysis Severity
  1. Biotechnology

AI Diagnoses Vocal Cord Paralysis Severity

In a groundbreaking advancement at the crossroads of artificial intelligence and clinical otolaryngology, researchers have unveiled an innovative platform that automatically assesses the severity of unilateral vocal cord paralysis (UVCP) using state-of-the-art deep learning techniques. This pioneering research leverages Mel-spectrograms—a sophisticated audio representation technique—paired with convolutional neural networks (CNN) to dissect subtle vocal characteristics, offering […]
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Good Reads

Scientists reprogram ant behavior using brain molecules

Scientists reprogram ant behavior using brain molecules

From the bright lights of cities that don’t sleep — where people hustle and bustle through the night to keep subways, servers, and supply chains alive — to the whisper-dark understory of tropical forests where ants hum in syncopated lines, the planet’s most intricate societies hinge on round-the-clock cooperation and finely tuned roles. Within Atta […]
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Mammals didn't walk upright until late—here's what fossils reveal

Mammals didn’t walk upright until late—here’s what fossils reveal

For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […]
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Worlwide

Scientists reprogram ant behavior using brain molecules

Scientists reprogram ant behavior using brain molecules

From the bright lights of cities that don’t sleep — where people hustle and bustle through the night to keep subways, servers, and supply chains alive — to the whisper-dark understory of tropical forests where ants hum in syncopated lines, the planet’s most intricate societies hinge on round-the-clock cooperation and finely tuned roles. Within Atta […]
Written by
Mammals didn't walk upright until late—here's what fossils reveal

Mammals didn’t walk upright until late—here’s what fossils reveal

For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […]
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A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores

Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […]
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