Biology A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells HaloTag technology represents a versatile tool for studying proteins. Fluorescent HaloTag ligands employed in sequential labeling led to the discovery of distinct protein variants for histones, cohesins, and MCM complexes. However, an efficient biochemical approach to separate these distinct protein variants to study their biological functions is missing. Principally, being a gap in technology, the […] Written by Admin July 17, 2025July 17, 2025 Saving Bookmark this article Bookmarked
Environmental Science Climate threatens ‘cascade of tipping points’ “The good news is that we know what to do to avert this – not least restoring nature and transitioning energy and food systems. But the time to act is now. Later is already too late. “Governments and businesses must rapidly align their policies and financial flows to limit global warming and halt the destruction […] Written by brendan July 17, 2025July 17, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development The Current issue of “The view from here” is concerned with Ophthalmology Sensory disorders are perhaps some of the most feared afflictions for individuals and of those, ocular conditions are potentially the most debilitating. Moreover, in many respects the physical structure of eyes makes the difficult job of drug discovery even more challenging as a result of the osmotic barrier represented by the physicochemical composition of the […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom July 17, 2025July 17, 2025 Saving Bookmark this article Bookmarked
Life Sciences The secret motor protein that slams leaf pores shut—and saves crops With intensifying global warming and climate change, drought has become a major threat to global agriculture, impacting crop yields and food security. To survive such adverse events, plants have evolved several strategies. One such strategy to counteract water scarcity is ‘stomatal closure,’ where stomata — the tiny pores on leaf surfaces responsible for gaseous exchange […] Written by Admin July 17, 2025July 17, 2025 Saving Bookmark this article Bookmarked
Life Sciences North america’s oldest pterosaur unearthed in Arizona’s Triassic time capsule A Smithsonian-led team of researchers have discovered North America’s oldest known pterosaur, the winged reptiles that lived alongside dinosaurs and were the first vertebrates to evolve powered flight. In a paper published on July 7 in Proceedings of the National Academy of Sciences, researchers led by paleontologist Ben Kligman, a Peter Buck Postdoctoral Fellow at […] Written by Admin July 16, 2025July 16, 2025 Saving Bookmark this article Bookmarked
Biology Flowering Plant Gene Regulation: Recruitment, Rewiring, Conservation In the sprawling and intricately wired world of plant genetics, transcription factors (TFs) have emerged as central conductors orchestrating gene expression. These proteins bind to discrete regions of DNA, known as transcription factor binding sites (TFBSs), modulating when and where genes become active. This process underpins every aspect of plant life, from cellular identity and […] Written by Bioengineer July 15, 2025July 15, 2025 Saving Bookmark this article Bookmarked
Environmental Science A Disaster Expert Explains Why the Texas Floods Were So Devastating – State of the Planet Flooding of the Guadalupe River near Kerrville, Texas, on June 5, 2025. Photo: U.S. Coast Guard As the past few weeks have shown, flash floods can develop very quickly in both rural and urban areas, with mild to catastrophic impacts. That’s part of why flash floods are so critical to study, according to Andrew Kruczkiewicz, […] Written by Adrienne Day July 15, 2025July 15, 2025 Saving Bookmark this article Bookmarked
Life Sciences Why monkeys—and humans—can’t look away from social conflict Have you ever wondered what kind of video content would most grab the attention of monkeys? A new study of long-tailed macaques suggests the monkeys seem to like some of the same kind of content that humans do: videos featuring aggression and individuals they know. “Humans and macaques are both social animals who have a […] Written by Admin July 15, 2025July 15, 2025 Saving Bookmark this article Bookmarked
Biotechnology The 59 top biotech books of all time Newsletter Signup – Under Article / In Page “*” indicates required fields It’s summertime and what’s better than to curl up in bed, or under a shady tree, or by the pool, and read a good book? We have curated a list of some of the best biotech books that are bound to get you […] Written by Roohi Mariam Peter July 14, 2025July 14, 2025 Saving Bookmark this article Bookmarked
Biology Nonmuscle myosin II regulates presynaptic actin and neuronal mechanobiology in Drosophila Neuromuscular junctions (NMJs) are evolutionarily ancient, specialized contacts between neurons and muscles. They experience lifelong strain, yet the mechanism preserving their integrity under mechanical load remains unclear. Here, we identify a novel actomyosin structure at Drosophila larval NMJs, consisting of a long-lived, low-turnover presynaptic actin core that colocalizes with nonmuscle myosin II (NMII) and becomes […] Written by Admin July 14, 2025July 14, 2025 Saving Bookmark this article Bookmarked
Environmental Science Afterwoke: from identity to unity The book tour for Minority Rule generated the kind of buzz most authors could only dream of. Ash Sarkar’s searing debut illustrates how culture wars keep most of the UK’s population divided. Buy: Minority Rule: Adventures in the Culture War by Ash Sarkar. A prominent left-wing journalist, writer, lecturer and political commentator, Sarkar made headlines […] Written by brendan July 14, 2025July 14, 2025 Saving Bookmark this article Bookmarked
Life Sciences This tiny rice plant could feed the first lunar colony The future of sustained space habitation depends on our ability to grow fresh food away from Earth. The revolutionary new collaborative Moon-Rice project is using cutting-edge experimental biology to create an ideal future food crop that can be grown in future deep-space outposts, as well as in extreme environments back on Earth. Modern space exploration […] Written by Admin July 14, 2025July 14, 2025 Saving Bookmark this article Bookmarked
