Admin's articles Pharmaceuticals and Drug Development Unicycive Therapeutics Announces Receipt of Complete Response Letter for Oxylanthanum Carbonate for the Treatment of Hyperphosphatemia in Patients with Chronic Kidney Disease on Dialysis LOS ALTOS, Calif., June 30, 2025 (GLOBE NEWSWIRE) — Unicycive Therapeutics, Inc. (“Unicycive” or the “Company”) (Nasdaq: UNCY), a clinical-stage biotechnology company developing therapies for patients with kidney disease… Written by Admin July 5, 2025July 5, 2025 Saving Bookmark this article Bookmarked Life Sciences 600-million-year-old body blueprint found in sea anemones A new study from the University of Vienna reveals that sea anemones use a molecular mechanism known from bilaterian animals to form their back-to-belly body axis. This mechanism (“BMP shuttling”) enables cells to organize themselves during development by interpreting signaling gradients. The findings, published in Science Advances, suggest that this system evolved much earlier than […] Written by Admin July 5, 2025July 5, 2025 Saving Bookmark this article Bookmarked Life Sciences The fatal mutation that lets cancer outsmart the human immune system New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates. This insight could lead to more powerful cancer treatments. The study was published in Nature Communications. It revealed a tiny genetic difference […] Written by Admin July 4, 2025July 4, 2025 Saving Bookmark this article Bookmarked Biology Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway The transition from meiotic divisions in the oocyte to embryonic mitoses is a critical step in animal development. Despite negligible changes to cell size and shape, following fertilization the small, barrel-shaped meiotic spindle is replaced by a large zygotic spindle that nucleates abundant astral microtubules at spindle poles. To probe underlying mechanisms, we applied a […] Written by Admin July 3, 2025July 3, 2025 Saving Bookmark this article Bookmarked Life Sciences The pandemic pet boom was real. The happiness boost wasn’t A new study challenges the belief in a universal “pet effect” on human well-being. Using data collected during COVID-19 lockdowns, researchers found no significant change in respondents’ well-being when they acquired or lost a pet in their household. The findings suggest that, even during a time of extreme isolation, human-animal bonds may not be as […] Written by Admin July 3, 2025July 3, 2025 Saving Bookmark this article Bookmarked Life Sciences Mining the deep could mute the songs of sperm whales Deep-sea mining in a remote part of the Pacific Ocean could harm ocean life including whales and dolphins, new research shows. The Clarion Clipperton Zone (CCZ) of the Eastern Pacific is a vast area of deep ocean and seamounts. A Canadian firm – The Metals Company – is planning to explore parts of the CCZ […] Written by Admin July 2, 2025July 2, 2025 Saving Bookmark this article Bookmarked Life Sciences Scientists reprogram ant behavior using brain molecules From the bright lights of cities that don’t sleep — where people hustle and bustle through the night to keep subways, servers, and supply chains alive — to the whisper-dark understory of tropical forests where ants hum in syncopated lines, the planet’s most intricate societies hinge on round-the-clock cooperation and finely tuned roles. Within Atta […] Written by Admin July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked Life Sciences Mammals didn’t walk upright until late—here’s what fossils reveal For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […] Written by Admin June 30, 2025June 30, 2025 Saving Bookmark this article Bookmarked Biology A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked Life Sciences Skull study shows Chicago’s rodents are rapidly evolving In general, evolution is a long, slow process of tiny changes passed down over generations, resulting in new adaptations and even new species over thousands or millions of years. But when living things are faced with dramatic shifts in the world around them, they sometimes rapidly adapt to better survive. Scientists recently found an example […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked Life Sciences These 545-million-year-old fossil trails just rewrote the story of evolution The Cambrian explosion was an extraordinary phenomenon in the evolution of life on the planet that led to the emergence of many animal phyla and the diversification of species. During this period, some 530 million years ago, most of the basic body plans of organisms that have survived to the present day emerged. However, this […] Written by Admin June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked Loading Load more
Pharmaceuticals and Drug Development Unicycive Therapeutics Announces Receipt of Complete Response Letter for Oxylanthanum Carbonate for the Treatment of Hyperphosphatemia in Patients with Chronic Kidney Disease on Dialysis LOS ALTOS, Calif., June 30, 2025 (GLOBE NEWSWIRE) — Unicycive Therapeutics, Inc. (“Unicycive” or the “Company”) (Nasdaq: UNCY), a clinical-stage biotechnology company developing therapies for patients with kidney disease… Written by Admin July 5, 2025July 5, 2025 Saving Bookmark this article Bookmarked
Life Sciences 600-million-year-old body blueprint found in sea anemones A new study from the University of Vienna reveals that sea anemones use a molecular mechanism known from bilaterian animals to form their back-to-belly body axis. This mechanism (“BMP shuttling”) enables cells to organize themselves during development by interpreting signaling gradients. The findings, published in Science Advances, suggest that this system evolved much earlier than […] Written by Admin July 5, 2025July 5, 2025 Saving Bookmark this article Bookmarked
Life Sciences The fatal mutation that lets cancer outsmart the human immune system New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates. This insight could lead to more powerful cancer treatments. The study was published in Nature Communications. It revealed a tiny genetic difference […] Written by Admin July 4, 2025July 4, 2025 Saving Bookmark this article Bookmarked
Biology Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway The transition from meiotic divisions in the oocyte to embryonic mitoses is a critical step in animal development. Despite negligible changes to cell size and shape, following fertilization the small, barrel-shaped meiotic spindle is replaced by a large zygotic spindle that nucleates abundant astral microtubules at spindle poles. To probe underlying mechanisms, we applied a […] Written by Admin July 3, 2025July 3, 2025 Saving Bookmark this article Bookmarked
Life Sciences The pandemic pet boom was real. The happiness boost wasn’t A new study challenges the belief in a universal “pet effect” on human well-being. Using data collected during COVID-19 lockdowns, researchers found no significant change in respondents’ well-being when they acquired or lost a pet in their household. The findings suggest that, even during a time of extreme isolation, human-animal bonds may not be as […] Written by Admin July 3, 2025July 3, 2025 Saving Bookmark this article Bookmarked
Life Sciences Mining the deep could mute the songs of sperm whales Deep-sea mining in a remote part of the Pacific Ocean could harm ocean life including whales and dolphins, new research shows. The Clarion Clipperton Zone (CCZ) of the Eastern Pacific is a vast area of deep ocean and seamounts. A Canadian firm – The Metals Company – is planning to explore parts of the CCZ […] Written by Admin July 2, 2025July 2, 2025 Saving Bookmark this article Bookmarked
Life Sciences Scientists reprogram ant behavior using brain molecules From the bright lights of cities that don’t sleep — where people hustle and bustle through the night to keep subways, servers, and supply chains alive — to the whisper-dark understory of tropical forests where ants hum in syncopated lines, the planet’s most intricate societies hinge on round-the-clock cooperation and finely tuned roles. Within Atta […] Written by Admin July 1, 2025July 1, 2025 Saving Bookmark this article Bookmarked
Life Sciences Mammals didn’t walk upright until late—here’s what fossils reveal For over a century, scientists have puzzled over a fundamental mystery in our evolutionary history: how did mammals go from sprawling like lizards to striding like cats and dogs? This transition — from a sprawled stance (like a lizard) to an upright (parasagittal) posture — marked a pivotal moment in mammal evolution. While the earliest […] Written by Admin June 30, 2025June 30, 2025 Saving Bookmark this article Bookmarked
Biology A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Life Sciences Skull study shows Chicago’s rodents are rapidly evolving In general, evolution is a long, slow process of tiny changes passed down over generations, resulting in new adaptations and even new species over thousands or millions of years. But when living things are faced with dramatic shifts in the world around them, they sometimes rapidly adapt to better survive. Scientists recently found an example […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Life Sciences These 545-million-year-old fossil trails just rewrote the story of evolution The Cambrian explosion was an extraordinary phenomenon in the evolution of life on the planet that led to the emergence of many animal phyla and the diversification of species. During this period, some 530 million years ago, most of the basic body plans of organisms that have survived to the present day emerged. However, this […] Written by Admin June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
