Biology Rewrite Repurposing the memory-promoting meclofenoxate hydrochloride as a Zhang, H., Fan, C., Li, L. et al. Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis.npj Parkinsons Dis. 11, 167 (2025). bu içeriği en az 2500 kelime olacak şekilde ve alt başlıklar ve madde içermiyecek şekilde ünlü bir science magazine için İngilizce olarak yeniden yaz. Teknik açıklamalar içersin […] Written by Bioengineer June 13, 2025June 13, 2025 Saving Bookmark this article Bookmarked
Environmental Science Building Mobility, Resilience and Connection in a Changing Climate – State of the Planet What does mobility look like in the face of climate change? How can we build more just and climate-resilient communities? When should areas opt for adaptation in place over managed retreat? These are just some of the questions to expect at this year’s MR2025 (formerly known as Managed Retreat) conference. Hosted by the Columbia Climate […] Written by Olga Rukovets June 13, 2025June 13, 2025 Saving Bookmark this article Bookmarked
Life Sciences Why past mass extinctions didn’t break ecosystems—But this one might Two major environmental shifts have triggered global transformations in large herbivore communities. A new study with researchers from the University of Gothenburg show how these ecosystems remained remarkably resilient despite extinction and upheaval. From mastodons to ancient rhinos and giant deer, large herbivores have been shaping Earth’s landscapes for millions of years. A new study, […] Written by Admin June 12, 2025June 12, 2025 Saving Bookmark this article Bookmarked
Life Sciences How madagascar’s lizards became the island’s last hope for reforestation After the island of Madagascar drifted away from India 88 million years ago, isolating it from all other landmasses, its flora and fauna evolved in seclusion. As these transformed into plants and animals completely unique to their island, Madagascar became a biodiversity hotspot unlike anywhere else on Earth. An important facet of this biodiversity is […] Written by Admin June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Biology Mitotic genome folding Mitotic genome folding, or mitotic chromosome assembly, is essential for the faithful segregation of genetic information into daughter cells. While this process was once thought to be highly complex, requiring a myriad of protein components, recent studies have begun to revise this conventional view. An emerging view is that the core reaction of mitotic genome […] Written by Admin June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Environmental Science Will green flood defences work? The results were mixed. While vegetation slightly reduced water depth and flow speed in some scenarios, it had little to no impact on the overall extent or timing of flooding. As sea levels rose, even these modest benefits faded. In essence, the study revealed that while nature can slow the floodwaters, it may not stop […] Written by brendan June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Biotechnology Scorpion, fresh off Lilly deal, spins out startup Antares Five months after selling a cancer drug to Lilly for up to $2.5 billion, Scorpion has debuted a successor company led by its former management team to chase “previously inaccessible” drug targets. Written by Ben Fidler June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Tenpoint Therapeutics Ltd. Announces FDA Acceptance of New Drug Application for Brimochol PF for the Treatment of Presbyopia LONDON, United Kingdom and SEATTLE, Wash., June 03, 2025 – Tenpoint Therapeutics, Ltd. (“Tenpoint”), a global, clinical-stage biotechnology company focused on developing groundbreaking treatments to rejuvenate vision in the aging… Written by Admin June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Life Sciences What a dinosaur ate 100 million years ago—Preserved in a fossilized time capsule Plant fossils found in the abdomen of a sauropod support the long-standing hypothesis that these dinosaurs were herbivores, finds a study published on June 9 in the Cell Press journal Current Biology. The dinosaur, which was alive an estimated 94 to 101 million years ago, ate a variety of plants and relied almost entirely on […] Written by Admin June 10, 2025June 10, 2025 Saving Bookmark this article Bookmarked
Life Sciences Take Care When Paying Volume-Based Compensation to Sales Agents to Avoid Anti-Kickback Statute Violations – Duane Morris Life Sciences Law By Frederick R. Ball, Coleen W. Hill and Victoria (Tori) Hawekotte Pharmaceutical companies sometimes compensate sales agents per volume sold. The Fifth and Seventh Circuits have indicated that a company may structure such arrangements without running afoul of the Anti-Kickback Statute (AKS). However, such arrangements carry risk of violating the AKS and should […] Written by Duane Morris June 9, 2025June 9, 2025 Saving Bookmark this article Bookmarked
Will green flood defences work? The results were mixed. While vegetation slightly reduced water depth and flow speed in some scenarios, it had little to no impact on the overall extent or timing of flooding. As sea levels rose, even these modest benefits faded. In essence, the study revealed that while nature can slow the floodwaters, it may not stop […] Written by brendan June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Scorpion, fresh off Lilly deal, spins out startup Antares Five months after selling a cancer drug to Lilly for up to $2.5 billion, Scorpion has debuted a successor company led by its former management team to chase “previously inaccessible” drug targets. Written by Ben Fidler June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Will green flood defences work? The results were mixed. While vegetation slightly reduced water depth and flow speed in some scenarios, it had little to no impact on the overall extent or timing of flooding. As sea levels rose, even these modest benefits faded. In essence, the study revealed that while nature can slow the floodwaters, it may not stop […] Written by brendan June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Scorpion, fresh off Lilly deal, spins out startup Antares Five months after selling a cancer drug to Lilly for up to $2.5 billion, Scorpion has debuted a successor company led by its former management team to chase “previously inaccessible” drug targets. Written by Ben Fidler June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Tenpoint Therapeutics Ltd. Announces FDA Acceptance of New Drug Application for Brimochol PF for the Treatment of Presbyopia LONDON, United Kingdom and SEATTLE, Wash., June 03, 2025 – Tenpoint Therapeutics, Ltd. (“Tenpoint”), a global, clinical-stage biotechnology company focused on developing groundbreaking treatments to rejuvenate vision in the aging… Written by Admin June 11, 2025June 11, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked