Life Sciences The 4x rule: Why some people’s DNA is more unstable than others A large scale genetic analysis of more than 900,000 people has revealed that specific regions of DNA become increasingly unstable over time. These regions are made up of very short sequences that repeat again and again, and the study shows that they tend to grow longer as people age. Researchers also found that common inherited […] Written by Admin January 10, 2026January 10, 2026 Saving Bookmark this article Bookmarked
Biology Mitochondrial presequences harbor variable strengths to maintain organellar function Hundreds of mitochondrial proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphiphilic helices, presequences lack a consensus motif and thus likely promote protein import into mitochondria with variable efficiencies. Indeed, the concept of presequence strength underlies biological models such as stress sensing, yet a quantitative analysis of […] Written by Admin January 9, 2026January 9, 2026 Saving Bookmark this article Bookmarked
Environmental Science Labour’s ‘deeply alarming’ attack on protest rights British authorities have severely restricted the right to protest in contravention of their international human rights obligations, creating an environment in which peaceful dissent is increasingly treated as a criminal act, Human Rights Watch said in its latest report. ‘Silencing the Streets’: The Right to Protest Under Attack in the UK documents that the UK’s […] Written by brendan January 9, 2026January 9, 2026 Saving Bookmark this article Bookmarked
Life Sciences Ancient skeletons reveal viruses embedded in human DNA Scientists have, for the first time, rebuilt ancient genomes of Human betaherpesvirus 6A and 6B (HHV-6A/B) using DNA from archaeological human remains that are more than 2,000 years old. The research, led by teams at the University of Vienna and the University of Tartu (Estonia) and published in Science Advances, shows that these viruses have […] Written by Admin January 9, 2026January 9, 2026 Saving Bookmark this article Bookmarked
Life Sciences FDA Launches the TEMPO Pilot for Digital Health Devices to Improve Patient Access to Technologies – Duane Morris Life Sciences Law By Vicki G. Norton, Ph.d., Frederick R. Ball and Victoria (Tori) Hawekotte The U.S. Food and Drug Administration has announced the Technology-Enabled Meaningful Patient Outcomes (TEMPO) for Digital Health Devices Pilot, through which FDA would exercise enforcement discretion over participant manufacturers’ digital health devices to improve patient access to digital health […] Written by Duane Morris January 8, 2026January 8, 2026 Saving Bookmark this article Bookmarked
Biotechnology Basilea pens collab with US biotech to develop new antifungal Basilea Pharmaceutica is continuing its quest to develop much-needed new antifungal drugs by penning a deal with Prokaryotics worth at least $48 million. Written by Admin January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Biology New Arabidopsis BIK1 Alleles Confirm Immunity Role In a groundbreaking study poised to redefine our understanding of plant immunity, researchers have unveiled novel insights into the pivotal roles of the receptor-like cytoplasmic kinases BIK1 and PBL1 in Arabidopsis. These kinases, previously studied primarily through single transfer DNA (T-DNA) insertional mutant alleles, are reaffirmed as central players in the plant’s pattern-triggered immunity (PTI) […] Written by Bioengineer January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Environmental Science Climate Action Costs More in the Global South. Here’s Why. – State of the Planet Clean energy technologies have become more affordable around the world. Yet for many countries in the Global South, the cost of transitioning to a low-carbon economy remains disproportionately high. But not because the equipment is more expensive: in fact, solar and wind components are often imported at comparable prices around the world, as global manufacturing scale and […] Written by Guest January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Corcept Receives Complete Response Letter for Relacorilant as a Treatment for Patients with Hypercortisolism REDWOOD CITY, Calif.–(BUSINESS WIRE)–Dec. 31, 2025– Corcept Therapeutics Incorporated (NASDAQ: CORT), a commercial-stage company engaged in the discovery and development of medications to treat severe endocrinologic, oncologic, metabolic and… Written by Admin January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Life Sciences The poison frog that fooled scientists for decades Scientists at the University of Kansas Biodiversity Institute and Natural History Museum recently uncovered a mistake that dates back decades involving a poison frog specimen from Peru. The frog had been incorrectly identified and designated as a holotype, which is the single preserved specimen used to officially define a species. While modern taxonomy may also […] Written by Admin January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Basilea pens collab with US biotech to develop new antifungal Basilea Pharmaceutica is continuing its quest to develop much-needed new antifungal drugs by penning a deal with Prokaryotics worth at least $48 million. Written by Admin January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
New Arabidopsis BIK1 Alleles Confirm Immunity Role In a groundbreaking study poised to redefine our understanding of plant immunity, researchers have unveiled novel insights into the pivotal roles of the receptor-like cytoplasmic kinases BIK1 and PBL1 in Arabidopsis. These kinases, previously studied primarily through single transfer DNA (T-DNA) insertional mutant alleles, are reaffirmed as central players in the plant’s pattern-triggered immunity (PTI) […] Written by Bioengineer January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Basilea pens collab with US biotech to develop new antifungal Basilea Pharmaceutica is continuing its quest to develop much-needed new antifungal drugs by penning a deal with Prokaryotics worth at least $48 million. Written by Admin January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
New Arabidopsis BIK1 Alleles Confirm Immunity Role In a groundbreaking study poised to redefine our understanding of plant immunity, researchers have unveiled novel insights into the pivotal roles of the receptor-like cytoplasmic kinases BIK1 and PBL1 in Arabidopsis. These kinases, previously studied primarily through single transfer DNA (T-DNA) insertional mutant alleles, are reaffirmed as central players in the plant’s pattern-triggered immunity (PTI) […] Written by Bioengineer January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Climate Action Costs More in the Global South. Here’s Why. – State of the Planet Clean energy technologies have become more affordable around the world. Yet for many countries in the Global South, the cost of transitioning to a low-carbon economy remains disproportionately high. But not because the equipment is more expensive: in fact, solar and wind components are often imported at comparable prices around the world, as global manufacturing scale and […] Written by Guest January 7, 2026January 7, 2026 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked