1. Biology
The Fanconi anemia (FA) DNA repair pathway is required for the repair of DNA interstrand cross-links (ICLs). ICLs are caused by genotoxins, such as chemotherapeutic agents or reactive aldehydes. Inappropriately repaired ICLs contribute to hematopoietic stem cell (HSC) failure and tumorigenesis. While endogenous acetaldehyde and formaldehyde are known to induce HSC failure and leukemia in […]
  1. Environmental Science
Soul-searching Second, the idea that repression of the movement would act as a ‘backfiring tool’, stirring public sympathy proved overly optimistic. “If they lock us up, there will be an outcry,” some activists claimed. Repression and court cases did not trigger mass support. Instead, the crackdowns dampened the movement’s momentum. Third, the rise of the […]
  1. Life Sciences
A giant, strong-jawed salamander once tunneled through ancient Tennessee soil. And thanks to a fossil unearthed near East Tennessee State University, scientists now better understand how it helped shape Appalachian amphibian diversity. The giant plethodontid salamander now joins the remarkable roster of fossils from the Gray Fossil Site & Museum. The findings appeared in the […]
  1. Biotechnology
In a groundbreaking advancement at the crossroads of artificial intelligence and clinical otolaryngology, researchers have unveiled an innovative platform that automatically assesses the severity of unilateral vocal cord paralysis (UVCP) using state-of-the-art deep learning techniques. This pioneering research leverages Mel-spectrograms—a sophisticated audio representation technique—paired with convolutional neural networks (CNN) to dissect subtle vocal characteristics, offering […]
  1. Life Sciences
In 1859, Darwin imagined evolution as a slow, gradual progress, with species accumulating small changes over time. But even he was surprised to find the fossil record offered no missing links: the intermediate forms which should have told this story step by step were simply not there. His explanation was as uncomfortable as it was […]
  1. Biology
In a comprehensive analysis spanning two decades, researchers have uncovered that serum uric acid (UA) concentrations and the prevalence of hyperuricemia have exhibited remarkable stability among adolescents in the United States. This longitudinal insight, meticulously documented in a recent study published in Pediatric Research, challenges prior assumptions about the possible upward trajectory of serum UA […]
  1. Environmental Science
Experts are warning that millions of people around the world aren’t being counted in census data, leaving policy makers in the dark about the populations they govern. They say a “quiet crisis” is unfolding with census data not being published due to concerns about declining response rates and the accuracy of data. In a paper […]
  1. Life Sciences
As a child, I was fascinated by reports and documentaries about field research and often wondered what it took to be there and what kind of knowledge was being produced. Later, as an ecologist, I felt the need for approaches that better connected scientific research with real-world contexts. I became especially interested in perspectives that […]
  1. Biology
In this issue, Nita et al. (https://doi.org/10.1083/jcb.202311030) show that the primary cilium regulates FGFR2 signalling through spatial compartmentalization, enabling selective downstream activation. Disruption of ciliary localization in disease-linked FGFR2 variants highlights the role of the cilium as a signalling gatekeeper in development and disease.

Good Reads

In a comprehensive analysis spanning two decades, researchers have uncovered that serum uric acid (UA) concentrations and the prevalence of hyperuricemia have exhibited remarkable stability among adolescents in the United States. This longitudinal insight, meticulously documented in a recent study published in Pediatric Research, challenges prior assumptions about the possible upward trajectory of serum UA […]
Experts are warning that millions of people around the world aren’t being counted in census data, leaving policy makers in the dark about the populations they govern. They say a “quiet crisis” is unfolding with census data not being published due to concerns about declining response rates and the accuracy of data. In a paper […]

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In a comprehensive analysis spanning two decades, researchers have uncovered that serum uric acid (UA) concentrations and the prevalence of hyperuricemia have exhibited remarkable stability among adolescents in the United States. This longitudinal insight, meticulously documented in a recent study published in Pediatric Research, challenges prior assumptions about the possible upward trajectory of serum UA […]
Experts are warning that millions of people around the world aren’t being counted in census data, leaving policy makers in the dark about the populations they govern. They say a “quiet crisis” is unfolding with census data not being published due to concerns about declining response rates and the accuracy of data. In a paper […]
As a child, I was fascinated by reports and documentaries about field research and often wondered what it took to be there and what kind of knowledge was being produced. Later, as an ecologist, I felt the need for approaches that better connected scientific research with real-world contexts. I became especially interested in perspectives that […]

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