Biology Dynamic interaction of spliceosomal snRNPs with coilin explains Cajal body characteristics The Cajal body (CB) is a conserved non-membrane nuclear structure where several steps of small nuclear RNP particle (snRNP) biogenesis take place. It has been proposed that CB formation follows a liquid–liquid phase separation model, but this hypothesis has never been rigorously tested. Here, we applied live-cell imaging to show that the key CB assembly […] Written by Admin June 26, 2025June 26, 2025 Saving Bookmark this article Bookmarked
Environmental Science The apocalypse of beauty 28 Years After will be the film of this summer. At times scary, funny and gloriously weird, it is a story about nature and our fears of it. As such, it is worth asking what the wildness is in its story which threatens to overwhelm us? The film is the third in a five-picture series. […] Written by brendan June 26, 2025June 26, 2025 Saving Bookmark this article Bookmarked
Life Sciences New viruses discovered in bats in China could be the next pandemic threat Researchers have discovered two new viruses in bats that are closely related to the deadly Nipah and Hendra viruses — pathogens that can cause severe brain inflammation and respiratory disease in humans. The viruses, as well as other new viruses, bacteria, and parasites identified from bat kidneys, were reported this week in the open-access journal […] Written by Admin June 25, 2025June 25, 2025 Saving Bookmark this article Bookmarked
Life Sciences These frozen wolf cubs ate a woolly rhino—and changed what we know about dogs New analysis of the remains of two ‘puppies’ dating back more than 14,000 years ago has shown that they are most likely wolves, and not related to domestic dogs, as previously suggested. The genetic analysis also proved that the cubs were sisters at the age of around two months, and like modern day wolves had […] Written by Admin June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
Biotechnology Lexeo to help launch spinout around RNA drugs for the heart Backed by Perceptive Xontogeny Venture Funds and venBio Partners, the new biotech will make genetic medicines that don’t rely on viral vectors. Written by Gwendolyn Wu June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
Biology Dispersion-Engineered Metasurfaces: Debye Relaxation Unveiled In the rapidly advancing domain of photonics and metamaterials, researchers continually seek novel pathways to manipulate light with precision and efficiency unachievable by conventional means. A groundbreaking study published in Light: Science & Applications by Ahmed, Qi, and Chen heralds a significant leap forward in our understanding and engineering of metasurfaces, focusing on the integration […] Written by Bioengineer June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
Environmental Science In Norway, Climate Goals Clash With Indigenous Herders’ Rights – State of the Planet A recent climate initiative by the Norwegian government is facing opposition from the Saami Indigenous people, whose territories are directly affected. The proposed 54-kilometer power line would be built by the state-owned energy company Equinor in the northernmost portion of the country, well above the Arctic Circle. The Saami believe their rights to cultural preservation […] Written by Guest June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
Life Sciences From cursed tomb fungus to cancer cure: Aspergillus flavus yields potent new drug Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient tombs, the researchers modified the chemicals and tested them against leukemia cells. The result? A promising cancer-killing compound that rivals FDA-approved […] Written by Admin June 23, 2025June 23, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development UK antibiotic subscription model key to supporting antibiotic investment For the world to meet the health challenge posed by increasing antimicrobial resistance (AMR), new ways must be found to overcome the market failure that holds back the development of new antibiotics. Critical to this is greater understanding of the factors needed to persuade investors to support research and development (R&D) efforts. The latest report […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom June 23, 2025June 23, 2025 Saving Bookmark this article Bookmarked
Life Sciences Frozen in time: Transparent worms keep genes in sync for 20 million years Two species of worms have retained remarkably similar patterns in the way they switch their genes on and off despite having split from a common ancestor 20 million years ago, a new study finds. The findings appear in the June 19 issue of the journal Science. “It was just remarkable, with this evolutionary distance, that […] Written by Admin June 22, 2025June 22, 2025 Saving Bookmark this article Bookmarked
Dispersion-Engineered Metasurfaces: Debye Relaxation Unveiled In the rapidly advancing domain of photonics and metamaterials, researchers continually seek novel pathways to manipulate light with precision and efficiency unachievable by conventional means. A groundbreaking study published in Light: Science & Applications by Ahmed, Qi, and Chen heralds a significant leap forward in our understanding and engineering of metasurfaces, focusing on the integration […] Written by Bioengineer June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
In Norway, Climate Goals Clash With Indigenous Herders’ Rights – State of the Planet A recent climate initiative by the Norwegian government is facing opposition from the Saami Indigenous people, whose territories are directly affected. The proposed 54-kilometer power line would be built by the state-owned energy company Equinor in the northernmost portion of the country, well above the Arctic Circle. The Saami believe their rights to cultural preservation […] Written by Guest June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
Dispersion-Engineered Metasurfaces: Debye Relaxation Unveiled In the rapidly advancing domain of photonics and metamaterials, researchers continually seek novel pathways to manipulate light with precision and efficiency unachievable by conventional means. A groundbreaking study published in Light: Science & Applications by Ahmed, Qi, and Chen heralds a significant leap forward in our understanding and engineering of metasurfaces, focusing on the integration […] Written by Bioengineer June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
In Norway, Climate Goals Clash With Indigenous Herders’ Rights – State of the Planet A recent climate initiative by the Norwegian government is facing opposition from the Saami Indigenous people, whose territories are directly affected. The proposed 54-kilometer power line would be built by the state-owned energy company Equinor in the northernmost portion of the country, well above the Arctic Circle. The Saami believe their rights to cultural preservation […] Written by Guest June 24, 2025June 24, 2025 Saving Bookmark this article Bookmarked
From cursed tomb fungus to cancer cure: Aspergillus flavus yields potent new drug Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient tombs, the researchers modified the chemicals and tested them against leukemia cells. The result? A promising cancer-killing compound that rivals FDA-approved […] Written by Admin June 23, 2025June 23, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked