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Biotechnology Zydus' phase 3 liver disease win tees up filing to challenge Gilead and Ipsen Zydus Therapeutics has racked up a phase 2b/3 win in primary biliary cholangitis, clearing the path to a filing to establish the company as a challenger to Gilead, Intercept Pharmaceuticals and Ipsen. Written by Admin August 30, 2025August 30, 2025 Saving Bookmark this article Bookmarked
Life Sciences Scientists discover armored “goblin monster” in prehistoric Utah A newly discovered, raccoon-sized armored monstersaurian from the Grand Staircase-Escalante National Monument in Southern Utah, United States, reveals a surprising diversity of large lizards at the pinnacle of the age of dinosaurs. Named for the goblin prince from J.R.R. Tolkien’s “The Hobbit,” the new species Bolg amondol also illuminates the sometimes-murky path that life traveled […] Written by Admin August 30, 2025August 30, 2025 Saving Bookmark this article Bookmarked
Biology Submembrane liprin-α1 clusters spatially localize insulin granule fusion Insulin granule fusion in pancreatic β cells localizes to where they contact the ECM of the islet capillaries. The mechanism(s) underpinning localization are unclear. Using glucose or high K+ stimulation or the global uncaging of Ca2+, we show granule fusion consistently focused to the β cell–ECM interface, suggesting a specific localization mechanism. We tested for […] Written by Admin August 29, 2025August 29, 2025 Saving Bookmark this article Bookmarked
Environmental Science Coal power made history The site of a decommissioned power station in Staffordshire is being transformed into new homes, a school and accessible green spaces. Rugeley Power Station joins a growing number of coal-fired power stations that have been or are in the process of being repurposed into mixed-use developments. Energy services firm Engie has been working on turning […] Written by brendan August 29, 2025August 29, 2025 Saving Bookmark this article Bookmarked
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Life Sciences Scientists recreate life’s first step: Linking amino acids to RNA Chemists at UCL have shown how two of biology’s most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of life four billion years ago. Amino acids are the building blocks of proteins, the “workhorses” of life essential to nearly every living process. But proteins cannot replicate or […] Written by Admin August 29, 2025August 29, 2025 Saving Bookmark this article Bookmarked
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