Biology A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. We show that cells modulate Stu2 kinetochore-microtubule localization by Polo-like kinase1/Cdc5-mediated phosphorylation of T866, near the […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Environmental Science ‘Crunch time’ on climate He said: “I certainly tend to be an optimistic person but if you do look at this year’s annual update, things are all moving in the wrong direction.” “They’re not only moving in the wrong direction, we’re seeing some unprecedented changes.” Reflecting on the IPCC reports, he said: “What we had hope to see by […] Written by brendan June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.1d6d3e17.1751188923.24ea6da9 Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Life Sciences Skull study shows Chicago’s rodents are rapidly evolving In general, evolution is a long, slow process of tiny changes passed down over generations, resulting in new adaptations and even new species over thousands or millions of years. But when living things are faced with dramatic shifts in the world around them, they sometimes rapidly adapt to better survive. Scientists recently found an example […] Written by Admin June 29, 2025June 29, 2025 Saving Bookmark this article Bookmarked
Biotechnology EU Commissioner Várhelyi revives Biotech Act for 2025 In a panel discussion at Medicines for Europe Annual Conference, EU Health Commissioner Olivér Várhelyi made a surprise announcement that the Commission will adopt the EU Biotech Act by the end of this year, citing growing “global challenges”. According to the EU Commission’s work programme, the legislation was initially scheduled for adoption in Q3 2025, […] Written by Thomas Gabrielczyk June 28, 2025June 28, 2025 Saving Bookmark this article Bookmarked
Life Sciences These 545-million-year-old fossil trails just rewrote the story of evolution The Cambrian explosion was an extraordinary phenomenon in the evolution of life on the planet that led to the emergence of many animal phyla and the diversification of species. During this period, some 530 million years ago, most of the basic body plans of organisms that have survived to the present day emerged. However, this […] Written by Admin June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Biology Consortium Seeks to Launch Major Carbon Removal Initiatives Experts in the field of carbon capture and climate solutions are coming together for a pivotal meeting in Exeter, aimed at spearheading the development of a new carbon economy. The New Carbon Economy Consortium (NCEC), a key player in the global effort to manage carbon emissions, will host its annual meeting at the University of […] Written by Bioengineer June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Environmental Science Columbia Climate School Students Take On Coastal Flooding at a U.N. Conference – State of the Planet Earlier this month, within a timeframe of less than 24 hours, a team of postgraduate and current students at the Columbia Climate School and the National Center for Disaster Preparedness (NCDP) worked through the night to develop and submit their entry for an international competition known as the U.N. Foresight Sprint. Part of the Global […] Written by Guest June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Life Sciences Can these endangered lizards beat the heat? Scientists test bold relocation plan Climate change and habitat loss are affecting animal populations around the world and reptiles such as South Australia’s own endangered pygmy bluetongue are susceptible to higher temperatures and declining long-term rainfall trends. Flinders University scientists are working on securing a sustainable future for the burrow-dwelling endemic skink (Tiliqua adelaidensis) by assessing their suitability to cooler […] Written by Admin June 26, 2025June 26, 2025 Saving Bookmark this article Bookmarked
Biology Dynamic interaction of spliceosomal snRNPs with coilin explains Cajal body characteristics The Cajal body (CB) is a conserved non-membrane nuclear structure where several steps of small nuclear RNP particle (snRNP) biogenesis take place. It has been proposed that CB formation follows a liquid–liquid phase separation model, but this hypothesis has never been rigorously tested. Here, we applied live-cell imaging to show that the key CB assembly […] Written by Admin June 26, 2025June 26, 2025 Saving Bookmark this article Bookmarked
These 545-million-year-old fossil trails just rewrote the story of evolution The Cambrian explosion was an extraordinary phenomenon in the evolution of life on the planet that led to the emergence of many animal phyla and the diversification of species. During this period, some 530 million years ago, most of the basic body plans of organisms that have survived to the present day emerged. However, this […] Written by Admin June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Consortium Seeks to Launch Major Carbon Removal Initiatives Experts in the field of carbon capture and climate solutions are coming together for a pivotal meeting in Exeter, aimed at spearheading the development of a new carbon economy. The New Carbon Economy Consortium (NCEC), a key player in the global effort to manage carbon emissions, will host its annual meeting at the University of […] Written by Bioengineer June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
These 545-million-year-old fossil trails just rewrote the story of evolution The Cambrian explosion was an extraordinary phenomenon in the evolution of life on the planet that led to the emergence of many animal phyla and the diversification of species. During this period, some 530 million years ago, most of the basic body plans of organisms that have survived to the present day emerged. However, this […] Written by Admin June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Consortium Seeks to Launch Major Carbon Removal Initiatives Experts in the field of carbon capture and climate solutions are coming together for a pivotal meeting in Exeter, aimed at spearheading the development of a new carbon economy. The New Carbon Economy Consortium (NCEC), a key player in the global effort to manage carbon emissions, will host its annual meeting at the University of […] Written by Bioengineer June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Columbia Climate School Students Take On Coastal Flooding at a U.N. Conference – State of the Planet Earlier this month, within a timeframe of less than 24 hours, a team of postgraduate and current students at the Columbia Climate School and the National Center for Disaster Preparedness (NCDP) worked through the night to develop and submit their entry for an international competition known as the U.N. Foresight Sprint. Part of the Global […] Written by Guest June 27, 2025June 27, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked
