Biotechnology FDA slaps hold on Denali's plans for phase 1 rare disease trial The FDA has placed a hold on Denali Therapeutics’ plans to launch a phase 1 rare disease trial, citing concerns about immune reactions to the investigational treatment recorded in preclinical mouse studies. Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked
Life Sciences Hornet-eating frog shows remarkable venom resistance A frog with an unexpectedly strong resistance to venom has been identified, and it routinely eats hornets despite the insects’ dangerous stingers. Researchers believe this species may become a useful model organism for exploring how animals develop tolerance to venom. For many people, even glimpsing a hornet’s stinger is enough to cause alarm. Yet certain […] Written by Admin December 5, 2025December 5, 2025 Saving Bookmark this article Bookmarked
Biology High-resolution mapping of the actin fusion focus reveals myosin V–dependent formin transport for aster formation Many processes such as polarized growth and secretion require specific actin networks. In fungi, cell–cell fusion requires cell wall digestion mediated by local secretion of lytic enzymes. In Schizosaccharomyces pombe, the myosin V Myo52 transports enzyme-containing secretory vesicles on the actin fusion focus, an aster-like actin network assembled by the condensate-forming formin Fus1. The fusion […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Environmental Science The hidden harm from salmon farming In addition to parasites, pathogens, chemical residues, and other treatments can persist in cages. Fallow sites are expected to undergo complete removal of fish and nets to limit pathogen carryover. Campaigners, however, say the Aird site “continued functioning as a reservoir of disease and flesh-eating lice.” Read: The catch. Unsustainable Abigail Penny, executive director of […] Written by brendan December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Life Sciences Doomed ants send a final scent to save their colony Ant societies behave like tightly integrated “superorganisms,” where thousands of individuals work together in a way that resembles the coordinated activity of cells in a body. Researchers at the Institute of Science and Technology Austria (ISTA) have found that terminally ill ant brood release a distinctive odor, similar to the way infected body cells send […] Written by Admin December 4, 2025December 4, 2025 Saving Bookmark this article Bookmarked
Life Sciences A tiny ocean worm just revealed a big secret about how eyes evolve A research team from the University of Vienna and the Alfred Wegener Institute in Bremerhaven has uncovered how the eyes of adult marine bristleworms continue to increase in size throughout their entire lifespan. The work shows that this constant growth is powered by a ring of neural stem cells that resembles similar structures found in […] Written by Admin December 3, 2025December 3, 2025 Saving Bookmark this article Bookmarked
Environmental Science Will Glacier Melt Lead to Increased Seismic Activity in Mountain Regions? – State of the Planet A recent study from Earth and Planetary Science Letters is the first to directly link earthquakes to climate change-induced glacial melt. Scientists analyzed 15 years of seismic activity in the Grandes Jorasses—a peak that is part of the Mont Blanc massif between Italy and France—to better understand this association. This massif is one of the […] Written by Guest December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.b0ed217.1764670323.277f7c81 Written by Admin December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked
Life Sciences Aligning Capital with Compliance and IP Value – Duane Morris Life Sciences Law By Driscoll R. Urgate, P.A. Financing and exit transactions in the life sciences industry differ fundamentally from those in traditional technology or manufacturing sectors. Scientific risk, regulatory oversight, and intellectual property rights intersect at every stage of a company’s growth, from seed capital through commercialization and acquisition. Investors and acquirers do […] Written by Duane Morris December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked
Biotechnology Angelini Ventures and EIB launch joint start-up financing As part of the TechEU initiative, the EIB and Angelini will co-invest €150m in high-potential biotechnology, medical technology, and digital health start-ups. Announced today at a press conference at Angelini Ventures’ headquarters in Rome, the initiative forms part of TechEU, the EIB Group’s investment programme to strengthen Europe’s innovation ecosystem and technological leadership. Through TechEU, […] Written by Thomas Gabrielczyk December 1, 2025December 1, 2025 Saving Bookmark this article Bookmarked
A tiny ocean worm just revealed a big secret about how eyes evolve A research team from the University of Vienna and the Alfred Wegener Institute in Bremerhaven has uncovered how the eyes of adult marine bristleworms continue to increase in size throughout their entire lifespan. The work shows that this constant growth is powered by a ring of neural stem cells that resembles similar structures found in […] Written by Admin December 3, 2025December 3, 2025 Saving Bookmark this article Bookmarked
Will Glacier Melt Lead to Increased Seismic Activity in Mountain Regions? – State of the Planet A recent study from Earth and Planetary Science Letters is the first to directly link earthquakes to climate change-induced glacial melt. Scientists analyzed 15 years of seismic activity in the Grandes Jorasses—a peak that is part of the Mont Blanc massif between Italy and France—to better understand this association. This massif is one of the […] Written by Guest December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked
A tiny ocean worm just revealed a big secret about how eyes evolve A research team from the University of Vienna and the Alfred Wegener Institute in Bremerhaven has uncovered how the eyes of adult marine bristleworms continue to increase in size throughout their entire lifespan. The work shows that this constant growth is powered by a ring of neural stem cells that resembles similar structures found in […] Written by Admin December 3, 2025December 3, 2025 Saving Bookmark this article Bookmarked
Will Glacier Melt Lead to Increased Seismic Activity in Mountain Regions? – State of the Planet A recent study from Earth and Planetary Science Letters is the first to directly link earthquakes to climate change-induced glacial melt. Scientists analyzed 15 years of seismic activity in the Grandes Jorasses—a peak that is part of the Mont Blanc massif between Italy and France—to better understand this association. This massif is one of the […] Written by Guest December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked
Access Denied Access Denied You don’t have permission to access ” on this server. Reference #18.b0ed217.1764670323.277f7c81 Written by Admin December 2, 2025December 2, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked