1. Clinical

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  1. Clinical

Unlocking the Potential of Clinical Trials for Improved Patient Outcomes

Clinical trials play a crucial role in enhancing patient outcomes and driving advancements in medical research. By unlocking the potential of clinical trials, we can gather important data, develop innovative therapies, and improve the overall quality of patient care. Clinical trials are essential in evaluating the safety and effectiveness of new treatments, drugs, and procedures. […]
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Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

A large international study of migraine reveals new biological pathways for treatment

REYKJAVIK, Iceland , Oct. 26, 2023. A large international study led by deCODE Genetics on the genetics of migraine provides novel insights into the biology of migraine enabling detection of rare variants protecting against migraine, opening an avenue for potential development of novel drug targets. In a study published today in Nature Genetics a group […]
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Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

Kisqali NATALEE analysis reinforces consistent reduction in risk of recurrence across key subgroups of patients with early breast cancer

Basel, October 20, 2023. Novartis will present late-breaking results from a prespecified exploratory subgroup analysis of invasive disease-free survival (iDFS) from the pivotal Phase III NATALEE trial at the European Society for Medical Oncology (ESMO) Congress 2023. After 27.7 months of follow-up, the iDFS benefit with Kisqal (ribociclib) plus endocrine therapy (ET) was consistent across […]
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Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

Datopotamab Deruxtecan Improved Progression-Free Survival vs. Chemotherapy in Patients with Previously Treated Non-Small Cell Lung Cancer in TROPION-Lung01 Phase III Trial

TROPION-Lung05 resultsInitial results from the TROPION-Lung05 Phase II trial showed datopotamab deruxtecan demonstrated encouraging antitumour activity in patients with heavily pretreated locally advanced or metastatic NSCLC with actionable genomic alterations including those with EGFR mutations and anaplastic lymphoma kinase (ALK) rearrangements. These data were presented at the ESMO 2023 Congress on Saturday, 21 October (1314MO). […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Rose important oil: A secure pesticide for natural agriculture

Vegetation-derived important oils (EOs) discover functions in varied industries, resembling detergents, cosmetics, pharmacology, and meals components. Furthermore, EOs have an distinctive security profile, and their quite a few bioactivities significantly profit human well being. Past these advantages, EOs have additionally been discovered to illicit insect-repellent responses by inducing neurotoxic results. Terpenoids are considerable in plant […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Large herbivores such as elephants, bison and moose contribute to tree diversity

Using global satellite data, a research team has mapped the tree cover of the world’s protected areas. The study shows that regions with abundant large herbivores in many settings have a more variable tree cover, which is expected to benefit biodiversity overall. Maintaining species-rich and resilient ecosystems is key to preserving biodiversity and mitigating climate […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Combined effects of plastic pollution and seawater flooding amplify threats to coastal plant species

Two of the planet’s more pressing environmental stressors have the potential to alter the growth and reproductive output of plants found right along the world’s coastlines, a new study suggests. The research, published in the journal Environmental Pollution, is one of the first to examine the combined effects of seawater flooding and microplastic pollution on […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

New viruses that might trigger epidemics on the horizon

Out of the blue they seem and — just like the SARS-CoV-2 coronavirus — can set off main epidemics: Viruses that no person had on their radar. They aren’t actually new, however they’ve modified genetically. Particularly, the trade of genetic materials between completely different virus species can result in the sudden emergence of threatening pathogens […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Multiple evolutionary trajectories in aquatic crocodiles

In the geological past, several groups of crocodiles evolved towards a morphology adapted to marine life. However, the extent of these adaptations and their evolutionary trajectories remained unknown. An exhaustive study of their morphology by a scientific team from the Evolution & Diversity Dynamics Lab (EDDyLab) at the University of Liège has now shed light […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Built-in dataset allows genes-to-ecosystems analysis

A primary-ever dataset bridging molecular details about the poplar tree microbiome to ecosystem-level processes has been launched by a workforce of Division of Vitality scientists led by Oak Ridge Nationwide Laboratory. The mission goals to tell analysis concerning how pure methods perform, their vulnerability to a altering local weather, and finally how crops may be […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Fish adjust reproduction in response to predators

Some species of fish can evolve their egg-laying habits in response to predators in the area in order to survive, according to new research from The University of Texas at Arlington. It has long been observed that organisms modify their traits, including reproductive patterns, in response to changes in their environment. This type of evolutionary […]
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  1. Biology

Two-in-one mapping of temperature and flow around microscale convective

Tokyo, Japan – Researchers from Tokyo Metropolitan University have devised a way to measure both the temperature and velocity profiles of fluid in a convective plume at millimeter length scales in 3D. They combined near-infrared absorption imaging and image processing to separate the motion of tracer particles from snapshots of how light is absorbed, producing […]
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  1. Biology

Samples from bottled water, tap water and household-treated tap water in

Samples from bottled water, tap water and household-treated tap water in San Francisco Bay Area indicate that all sources may have potential health risks, largely from trihalomethanes. Credit: SimpleLab, Inc. Redistribution permitted with credit given to the creator, SimpleLab, Inc. Samples from bottled water, tap water and household-treated tap water in San Francisco Bay Area […]
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  1. Biology

Fern becomes first in suborder to be classed as “independent

Tokyo, Japan – Researchers from Tokyo Metropolitan University have discovered that the fern Hymenasplenium murakami-hatanakae can become independent gametophytes i.e. live for long periods without a spore-producing sporophyte. They collected specimens from Izu-Oshima Island, Japan, and used DNA analysis to show that this Aspleniineae fern, a suborder encompassing thirty percent of ferns on the planet, […]
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  1. Nonclinical

From Bedside to Boardroom: Thriving in Nonclinical Leadership Roles

Title: From Bedside to Boardroom: Thriving in Nonclinical Leadership Roles Introduction: Transitioning from a clinical role to a nonclinical leadership position can be an exciting and rewarding career move for healthcare professionals. With their unique skill set and intimate understanding of the healthcare industry, these individuals bring a fresh perspective and valuable insights to the […]
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Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Pharmaceuticals and Drug Development

FDA Approves Arcutis’ Zoryve (roflumilast) Cream 0.15% for the Treatment of Atopic Dermatitis in Adults and Children Down to 6 Years of Age

WESTLAKE VILLAGE, Calif., July 09, 2024 (GLOBE NEWSWIRE) — Arcutis Biotherapeutics, Inc. (Nasdaq: ARQT), a commercial-stage biopharmaceutical company focused on developing meaningful innovations in immuno-dermatology, today announced the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application (sNDA) for Zoryve (roflumilast) cream, 0.15%, for the treatment of mild to moderate atopic […]
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One-Day Induction of XR Buprenorphine Feasible for Fentanyl Use in OUD
  1. Pharmaceuticals and Drug Development

One-Day Induction of XR Buprenorphine Feasible for Fentanyl Use in OUD

Medically reviewed by Drugs.com. By Elana Gotkine HealthDay Reporter WEDNESDAY, Nov. 8, 2023 — For individuals with opioid use disorder (OUD) using fentanyl, a one-day induction of extended‐release buprenorphine is a feasible treatment approach, according to a study published online Nov. 8 in the American Journal on Addiction. John J. Mariani, M.D., from the New […]
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