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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Healthy eating in midlife linked to overall healthy aging

Maintaining a healthy diet rich in plant-based foods, with low to moderate intake of healthy animal-based foods and lower intake of ultra-processed foods, was linked to a higher likelihood of healthy aging — defined as reaching age 70 free of major chronic diseases and with cognitive, physical, and mental health maintained, according to a new […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Tracing the evolution of ferns’ surprisingly sweet defense strategy

Plants and the animals that eat them have evolved together in fascinating ways, creating a dynamic interplay of survival strategies. Many plants have developed physical and chemical defenses to fend off herbivores. A well-known strategy in flowering plants is to produce nectar to attract “ant bodyguards.” Recent research explores the evolution of this same defense […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Cancer cells may be using lipids to hide from the immune system

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body’s defenses can swoop in, destroying rogue cells before they can do much damage. Lying at the heart of this early warning system are lipids, […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Rethinking the dodo | ScienceDaily

Researchers are setting out to challenge our misconceptions about the Dodo, one of the most well-known but poorly understood species of bird. In a paper published today [16 August 2024] in the Zoological Journal of the Linnean Society researchers from the University of Southampton, Natural History Museum (NHM) and Oxford University Museum of Natural History […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Warmth stress from ocean warming harms octopus imaginative and prescient

Whereas local weather change has led to a rise within the abundance of octopuses, warmth stress from projected ocean warming may impair their imaginative and prescient and affect the survivability of the species. “We discovered a number of proteins essential for imaginative and prescient that have been affected by thermal stress,” says Dr Qiaz Hua, […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

The rhythm led by plants is crucial for symbiosis with nutrient-providing bacteria

Legumes thrive in low-nitrogen environments by partnering with rhizobia, soil bacteria that convert atmospheric nitrogen into ammonium, a usable form for the plants. These beneficial bacteria are housed in root nodules formed on legume roots. However, the uncontrolled formation of numerous root nodules can impede root function. To prevent this, legumes need to regulate the […]
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Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Humpbacks are among animals who manufacture and wield tools

In a study published today in Royal Society Open Science, researchers at the Marine Mammal Research Program (MMRP) at UH Hawai’i Institute of Marine Biology (HIMB) and Alaska Whale Foundation (AWF) consider a new designation of the humpback whales they study: tool wielders. Researchers have known that humpback whales create “bubble-nets” to hunt, but they […]
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  1. Clinical

Clover Announces Positive Preliminary Phase Ⅰ Results for Bivalent RSV Vaccine Candidate SCB-1019 in Older Adults

SHANGHAI, June 18, 2024. Clover Biopharmaceuticals, Ltd. (Clover), a global commercial-stage biotechnology company committed to unleashing the power of innovative vaccines to save lives and improve health around the world, today announced positive preliminary immunogenicity and safety data in the older adult & elderly cohort from its Phase Ⅰ trial evaluating SCB-1019 – the company’s bivalent […]
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  1. Clinical

Harnessing the Power of Clinical Trials for Health and Wellness

Clinical trials play a crucial role in advancing health and wellness by harnessing the power of scientific research to develop innovative treatments, therapies, and preventive measures. These trials are carefully designed studies that evaluate the effectiveness and safety of new drugs, medical devices, diagnostic tools, or interventions. The primary goal of clinical trials is to […]
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  1. Clinical

AbbVie Announces Positive Topline Results from Phase 2 Trial Evaluating Elahere for High Folate Receptor-Alpha Expressing Platinum-Sensitive Ovarian Cancer

NORTH CHICAGO, Ill., June 6, 2024. AbbVie announced today positive topline results from the Phase 2 PICCOLO trial evaluating investigational mirvetuximab soravtansine (ELAHERE) monotherapy in heavily pre-treated patients with folate receptor-alpha (FRα) positive, platinum-sensitive ovarian cancer (PSOC). The study met its primary endpoint with an objective response rate (ORR) of 51.9% (95%CI 40.4 – 63.3%). […]
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Study Looks at Palliative Care Use in Adolescents, Young Adults With Cancer
  1. Pharmaceuticals and Drug Development

Study Looks at Palliative Care Use in Adolescents, Young Adults With Cancer

By Elana Gotkine HealthDay Reporter FRIDAY, Oct. 20, 2023 — For adolescents and young adults (AYA) with cancer, the likelihood of receiving specialty palliative care (SPC) is increased for those reporting moderate or severe symptoms, according to a study published online Oct. 20 in JAMA Network Open. Sumit Gupta, M.D., Ph.D., from The Hospital for […]
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  1. Biology

Study identifies biomarker that could predict whether colon cancer patients

MIAMI, FLORIDA (July 25, 2024) – Many people with stage II or III colon cancer receive additional, or adjuvant, chemotherapy following surgery. However, clinical trials have shown that this treatment doesn’t improve the chances of survival for every patient. A study published July 25 in Cell Reports Medicine identifies and validates a 10-gene biomarker that […]
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  1. Biology

Turning bacteria into bioplastic factories

In a world overrun by petroleum-based plastics, scientists are searching for alternatives that are more sustainable, more biodegradable and far less toxic to the environment. In a world overrun by petroleum-based plastics, scientists are searching for alternatives that are more sustainable, more biodegradable and far less toxic to the environment. Two new studies by biologists […]
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  1. Biology

RAB-10 cooperates with EHBP-1 to capture vesicular carriers during post-Golgi exocytic trafficking

Post-Golgi exocytic trafficking, fundamental for secretion and cell surface component integration, remains incompletely understood at the molecular level. Here, we investigated this process using Caenorhabditis elegans and mammalian cell models, revealing a novel exocytic carrier capturing mechanism involving the small GTPase RAB-10/Rab10 and its effector EHBP-1/EHBP1. EHBP-1, localized in recycling endosomes, selectively captures RAB-10-positive lipoprotein […]
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  1. Biology

What role did fear play in Europe’s population growth?

[Vienna, August 26 2024] – Since the end of the last Ice Age, growth of human population was far from uniform, marked instead by periods of rapid expansion followed by sharp declines. The reasons behind these fluctuations remain only partially understood. Previous research by CSH scientists Peter Turchin, Daniel Kondor, and an international team of collaborators, demonstrated […]
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  1. Biology

Stairway to the Golgi: Two paths VPS13B can go by

VPS13 proteins mediate lipid transfer across membranes. Among them, VPS13B is associated with Golgi membranes, and VPS13B mutations cause Cohen syndrome. In this issue, Ugur et al. (https://doi.org/10.1083/jcb.202311189) and Du et al. (https://doi.org/10.1083/jcb.202402083) reveal new VPS13B interactors and their functions in Golgi organization and trafficking. Admin Member since October 11, 2023 Loading + Follow Following
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  1. Biology

Structural insights into the coupling between VCP, an essential unfoldase, and a deubiquitinase

Proteostasis involves degradation and recycling of proteins from organelles, membranes, and multiprotein complexes. These processes can depend on protein extraction and unfolding by the essential mechanoenzyme valosin-containing protein (VCP) and on ubiquitin chain remodeling by ubiquitin-specific proteases known as deubiquitinases (DUBs). How the activities of VCP and DUBs are coordinated is poorly understood. Here, we […]
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