Biotechnology the power of TLR agonists Newsletter Signup – Under Article / In Page “*” indicates required fields In the vast field of immunotherapy, toll-like receptor agonists (TLR) emerged as powerful catalysts to boost the immune system. This class of drugs is designed to mimic the body’s natural defense mechanisms and target a spectrum of diseases – from cancer and infectious […] Written by Roohi Mariam Peter May 9, 2025May 9, 2025 Saving Bookmark this article Bookmarked
Life Sciences AI-designed DNA controls genes in healthy mammalian cells for first time A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. Researchers at the Centre for Genomic Regulation (CRG) created an AI tool which dreams up DNA regulatory sequences not seen before in nature. The model can […] Written by Admin May 8, 2025May 8, 2025 Saving Bookmark this article Bookmarked
Biology CDK4/6 Inhibitors Boost First-Line Breast Cancer Therapy In an ambitious stride toward optimizing treatment for hormone receptor-positive (HR+)/HER2-negative advanced breast cancer, a recent comprehensive network meta-analysis has brought fresh insights into the comparative efficacy and safety of the four widely used CDK4/6 inhibitors combined with aromatase inhibitors (AI). Published in the upcoming 2025 volume of BMC Cancer, this pioneering study meticulously synthesizes […] Written by Bioengineer May 8, 2025May 8, 2025 Saving Bookmark this article Bookmarked
Environmental Science All of the Biggest U.S. Cities Are Sinking – State of the Planet A new study of the 28 most populous U.S. cities finds that all are sinking to one degree or another. The cities include not just those on the coasts, where relative sea level is a concern, but many in the interior. Furthermore, using newly granular data, the study finds that some cities are sinking at […] Written by Kevin Krajick May 8, 2025May 8, 2025 Saving Bookmark this article Bookmarked
Life Sciences Triassic fossil reveals nature’s best jaw for hunting fast fish The best jaw for hunting fast fish is long and full of sharp teeth. This makes sense to us, but it also makes sense in nature: New fossil evidence from Virginia Tech geoscientists revealed that different species of predatory fish independently evolved similar jaw structure hundreds of millions of years apart. “The same evolutionary problem […] Written by Admin May 7, 2025May 7, 2025 Saving Bookmark this article Bookmarked
Life Sciences Two new crocodile species discovered McGill University researchers, in collaboration with Mexican scientists, have discovered two previously unknown species of crocodiles, one living on the island of Cozumel and the other on the atoll of Banco Chinchorro, both off the Yucatán Peninsula. The findings challenge long-held assumptions about the American crocodile (Crocodylus acutus) and highlight the urgent need for conservation […] Written by Admin May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Biology Rewrite Longitudinal profiling of low-abundance strains in microbiomes with The ability to detect and quantify microbiota over time from shotgun metagenomic data has a plethora of clinical, basic science and public health applications. Given these applications, and the observation that pathogens and other taxa of interest can reside at low relative abundance, there is a critical need for algorithms that accurately profile low-abundance microbial […] Written by Bioengineer May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Environmental Science Queering conservation In the way that queer theory recognises the importance of fluidity – particularly with regard to identity and sexuality as fluid and changeable phenomena, queer ecology challenges the mindset of ‘fixedness’ that upholds heterosexist notions of fixed identity, sexuality and gender roles. It challenges western science’s rigid categorisation, reductionism with its implicit heterosexist assumptions, and […] Written by brendan May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Pharmaceuticals and Drug Development How AI is Transforming Drug Discovery: Bio-IT World Europe Participants to Share Groundbreaking Advances 29-30 November in London LONDON, Nov. 6, 2023 — The life sciences profession is in the midst of a profound transformation, guided by the revolutionary force of artificial intelligence (AI), and especially predictive and generative AI models. These state-of-the-art technologies are leading the charge—expediting drug discovery and development, catalyzing innovation, and uncovering potential new therapies for cancer, heart disease, […] Written by Elsevier Ltd, The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Life Sciences Saving the Asian ‘unicorn’ — if it still exists Is it extinct, or does it still roam somewhere deep in the misty highland forests of Vietnam and Laos? It has been nicknamed the Asian unicorn due to its almost mythical rarity, and it is the most recently discovered large land mammal, becoming known to science as late as in 1992. Even then, it was […] Written by Admin May 5, 2025May 5, 2025 Saving Bookmark this article Bookmarked
Two new crocodile species discovered McGill University researchers, in collaboration with Mexican scientists, have discovered two previously unknown species of crocodiles, one living on the island of Cozumel and the other on the atoll of Banco Chinchorro, both off the Yucatán Peninsula. The findings challenge long-held assumptions about the American crocodile (Crocodylus acutus) and highlight the urgent need for conservation […] Written by Admin May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Rewrite Longitudinal profiling of low-abundance strains in microbiomes with The ability to detect and quantify microbiota over time from shotgun metagenomic data has a plethora of clinical, basic science and public health applications. Given these applications, and the observation that pathogens and other taxa of interest can reside at low relative abundance, there is a critical need for algorithms that accurately profile low-abundance microbial […] Written by Bioengineer May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Two new crocodile species discovered McGill University researchers, in collaboration with Mexican scientists, have discovered two previously unknown species of crocodiles, one living on the island of Cozumel and the other on the atoll of Banco Chinchorro, both off the Yucatán Peninsula. The findings challenge long-held assumptions about the American crocodile (Crocodylus acutus) and highlight the urgent need for conservation […] Written by Admin May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Rewrite Longitudinal profiling of low-abundance strains in microbiomes with The ability to detect and quantify microbiota over time from shotgun metagenomic data has a plethora of clinical, basic science and public health applications. Given these applications, and the observation that pathogens and other taxa of interest can reside at low relative abundance, there is a critical need for algorithms that accurately profile low-abundance microbial […] Written by Bioengineer May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Queering conservation In the way that queer theory recognises the importance of fluidity – particularly with regard to identity and sexuality as fluid and changeable phenomena, queer ecology challenges the mindset of ‘fixedness’ that upholds heterosexist notions of fixed identity, sexuality and gender roles. It challenges western science’s rigid categorisation, reductionism with its implicit heterosexist assumptions, and […] Written by brendan May 6, 2025May 6, 2025 Saving Bookmark this article Bookmarked
Understanding PMDA Validation Rules v5.0 The Pharmaceuticals and Medical Devices Agency (PMDA) in Japan has always led the charge in ensuring the safety and efficacy of drug development. Their latest update, the PMDA Validation Rules version 5.0, which took effect on April 1, 2024, marks another significant step in this mission. Let’s break down what these new rules mean and […] Written by Admin July 10, 2024July 10, 2024 Saving Bookmark this article Bookmarked
Enhance Your SEND Submissions! Join PointCross on May 29th, 2024, at 12 PM EST / 9 AM PST for a must-attend webinar: The Most Common Issues in Preparing SEND. Ideal for professionals in data submission and regulatory compliance, this webinar offers valuable insights from our seasoned experts. Why Attend? Why PointCross? With over 10 years of experience and more […] Written by Admin May 23, 2024May 23, 2024 Saving Bookmark this article Bookmarked