1. Pharmaceuticals and Drug Development

KalVista Announces FDA Acceptance of New Drug Application for Sebetralstat for Oral On-Demand Treatment of Hereditary Angioedema

Written by Posted on Less than 0 min read

CAMBRIDGE, Mass. & SALISBURY, England–(BUSINESS WIRE)–Sep. 3, 2024– KalVista Pharmaceuticals, Inc. (NASDAQ: KALV), today announced that the U.S. Food and Drug Administration (FDA) has accepted its New Drug Application (NDA) for sebetralstat…

Member since

More from Admin

Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Evolution of taste: Early sharks were able to perceive bitter substances

A research team from the University of Cologne, in collaboration with colleagues from the Leibniz Institute for Food Systems Biology in Freising, has discovered a receptor for bitter taste in twelve different cartilaginous fish (sharks and rays). The receptor belongs to the so-called taste receptors type 2 (T2R), which also make humans perceive bitter and […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

New report holder for smallest dispersers of ingested seeds: Woodlice

Even bugs as small as woodlice can disperse seeds they eat, setting a brand new report for smallest animal recorded to take action. The Kobe College discovery underscores the essential but typically ignored function that small invertebrates play in ecosystems. Many vegetation supply fruit to animals in order that in addition they eat the seeds […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Microbes in mouth reflect lifestyle choices

Lifestyle can shape the composition of beneficial bacteria and other microorganisms within the mouth, according to a new study led by Penn State biologists. The international team revealed how the “oral microbiome” differs over a range of subsistence strategies — from nomadic hunter gatherers to farmers to industrialized groups — and found that lifestyle, as […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Genes linked to deadly parasites’ spread beyond Africa identified

The findings reveal that climate change and measures to control populations of tsetse flies, which carry the disease, may drive molecular changes in the organisms that cause sleeping sickness — which can be fatal if left untreated. The parasites — known as African trypanosomes — are normally transmitted by tsetse flies in sub-Saharan Africa. However, […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

As human activities expand in Antarctica, scientists identify crucial conservation sites

A team of scientists led by the University of Colorado Boulder has identified 30 new areas critical for conserving biodiversity in the Southern Ocean surrounding Antarctica. In a study published Aug. 15 in the journal Conservation Biology, the researchers warn that without greater protection to limit human activities in these areas, native wildlife could face […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Cell’s ‘rubbish disposal’ could have one other position: Serving to neurons close to pores and skin sense the atmosphere

The standard job of the proteasome, the rubbish disposal of the cell, is to grind down proteins into smaller bits and recycle a few of these bits and components. That is nonetheless the case, for essentially the most half, however, Johns Hopkins Drugs researchers, finding out nerve cells grown within the lab and mice, say […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Antarctic ‘greening’ at dramatic rate

Vegetation cover across the Antarctic Peninsula has increased more than tenfold over the last four decades, new research shows. The Antarctic Peninsula, like many polar regions, is warming faster than the global average, with extreme heat events in Antarctica becoming more common. The new study — by the universities of Exeter and Hertfordshire, and the […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Key protein for the biosynthesis of defense steroids in solanaceous plants discovered

Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum. The new study published in Science shows that the protein is essential for the formation of these natural products from a cholesterol […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Acute sense of touch helps hummingbirds hover near a flower without bumping into it

Hummingbirds seem like a marvel of nature and engineering: a living creature that can hover near a flower with surgical precision. How do they do this? Though hummingbirds’ flight mechanics have been well studied, far less is known about how their sense of touch helps these tiny, energetic birds sip nectar from a flower without […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Generation of rat offspring from ovarian oocytes by cross-species transplantation

The idea of maturing oocytes in the ovary to produce offspring has been implemented in various ways. One such method, ovarian transplantation, is a relatively simple procedure for obtaining eggs, compared to in vitro culture of ovaries and follicles. However, it is still difficult to transplant ovaries into cellular immunodeficient mice and produce offspring from […]
Written by
  1. Clinical

Repurposed Drug Fenoprofen Exhibits Promise Towards Endometriosis-Associated Ache in Animal Mannequin

March 18, 2024 — Fenoprofen, a nonsteroidal anti-inflammatory drug (NSAID), efficiently alleviated ache and irritation in a rodent mannequin of endometriosis, in response to researchers funded by the Nationwide Institutes of Well being (NIH). They selected the drug after utilizing a pc algorithm to guage practically 1,300 current compounds for his or her skill to […]
Written by
Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

Amgen Presents New Data From Phase 2 Trial of Dazodalibep in Sjögren’s Syndrome

THOUSAND OAKS, Calif., Nov. 7, 2023. Amgen (NASDAQ:AMGN) today announced new data from its Phase 2 study evaluating dazodalibep, an investigational medicine, for the treatment of Sjögren’s. These results will be featured in presentations at the American College of Rheumatology (ACR) Convergence 2023, Nov. 10-15, in San Diego. Findings from the study demonstrate that dazodalibep […]
Written by
  1. Clinical

TCBP Announces Dosing of 6th Patient in ACHIEVE Study in Patients with Acute Myeloid Leukemia

EDINBURGH, Scotland, July 22, 2024. TC BioPharm (Holdings) PLC (“TC BioPharm” or the “Company”), a clinical stage biotechnology company developing platform allogeneic gamma-delta T cell therapies for cancer and other indications, today announced that on July 16, the sixth patient in ACHIEVE (UK) was treated. This is the first patient treated with a higher dose […]
Written by
Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

Gilead and Arcus Announce New Data Showing Encouraging Clinical Activity of Anti-TIGIT Domvanalimab-Containing Regimen as First-line Treatment for Upper GI Cancers

Preliminary data from Arm A1 of the Phase 2 EDGE-Gastric study showed promising ORR and six-month PFS results, irrespective of PD-L1 expression Domvanalimab is the only Fc-silent anti-TIGIT antibody in Phase 3 for upper GI adenocarcinomas and has the potential to be first to market for these cancers FOSTER CITY, Calif., & […]
Written by
  1. Biology

Locomotion control of cyborg insects by charge-balanced biphasic electrical

A research paper by scientists at Beijing Institute of Technology proposed a universal system for remote signal output control using infrared signals. Credit: Jieliang Zhao, School of Mechanical Engineering, Beijing Institute of Technology. A research paper by scientists at Beijing Institute of Technology proposed a universal system for remote signal output control using infrared signals. […]
Written by
  1. Biology

Revolutionary microfluidic sensors enable real-time detection of multiple

Recently, a group of researchers from Institute of Solid State Physics, the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, designed and developed advanced microfluidic sensor arrays that use fluorescent probes to simultaneously visualize and quantitatively detect multiple heavy metal ions in environmental water in real-time. Recently, a group of researchers from Institute of Solid […]
Written by
  1. Nonclinical

Pursuing a different calling: Embracing nonclinical career opportunities as a physician

Pursuing a Different Calling: Embracing Nonclinical Career Opportunities as a Physician As a physician, you have dedicated years of your life to the study and practice of medicine. You have honed your clinical skills, cared for countless patients, and made a significant impact on the lives of others. However, you may find yourself yearning for […]
Written by
Next
No Comments
Leave a comment Cancel
Comments to: KalVista Announces FDA Acceptance of New Drug Application for Sebetralstat for Oral On-Demand Treatment of Hereditary Angioedema

Login

Welcome to Life Science News!
"Explore the Latest Discoveries and Breakthroughs in Life Science with Life Science News!"
Read Smart, Save Time
Pick all the topics you are interested in to fill your homepage with stories you'll love.
Join our community
Registration is closed.