1. Pharmaceuticals and Drug Development

Stealth BioTherapeutics Announces Positive Vote from FDA Advisory Committee Meeting Supporting Potential Approval of Elamipretide for the Treatment of Barth Syndrome

Written by Posted on Less than 0 min read

NEEDHAM, Mass., Oct. 11, 2024 /PRNewswire/ — Stealth BioTherapeutics Inc. (the “Company” or “Stealth”), a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel…

Member since

More from Admin

  1. Biology

As dogs age, their owner-assessed quality of life predictably declines,

As dogs age, their owner-assessed quality of life predictably declines, with higher mortality seen at quality of life below 76% of the maximum score – though many dogs have high quality of life even when at predicted lifespan Credit: Juli Leonard for the Canine Neuroaging Program, CC-BY 4.0 ( As dogs age, their owner-assessed quality […]
Written by
  1. Biology

A proteome-wide yeast degron collection for the dynamic study of protein function

Genome-wide collections of yeast strains, known as libraries, revolutionized the way systematic studies are carried out. Specifically, libraries that involve a cellular perturbation, such as the deletion collection, have facilitated key biological discoveries. However, short-term rewiring and long-term accumulation of suppressor mutations often obscure the functional consequences of such perturbations. We present the AID library […]
Written by
  1. Biology

Collaborative research to benefit coastal flounder populations and fishers

Four faculty members from three departments in the College of Natural Resources and Environment have received $1.7 million from the National Science Foundation to fund research into the dynamics of socio-environmental factors impacting coastal fisheries. Credit: Photo by Lee Friesland for Virginia Tech. Four faculty members from three departments in the College of Natural Resources […]
Written by
  1. Biology

Distinct roles of two homologous kinesins in mammalian motile cilia

How do the two kinesin-9 members Kif6 and Kif9 function in mammalian cilia? Ou and colleagues discuss new work from Fang et al. (https://doi.org/10.1083/jcb.202312060) showing that Kif6 is an active motor while Kif9 serves as a stationary regulator, both of which are essential for cilia motility. Admin Member since October 11, 2023 Loading + Follow […]
Written by
  1. Biology

Securin regulates the spatiotemporal dynamics of separase

Separase regulates multiple aspects of the metaphase-to-anaphase transition. Separase cleaves cohesin to allow chromosome segregation and localizes to vesicles to promote exocytosis. The anaphase-promoting complex/cyclosome (APC/C) activates separase by ubiquitinating its inhibitory chaperone, securin, triggering its degradation. How this pathway controls the exocytic function of separase is unknown. During meiosis I, securin is degraded over […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Human-wildlife overlap expected to increase across more than half of land on Earth by 2070

As the human population grows, more than half of Earth’s land will experience an increasing overlap between humans and animals by 2070, according to a University of Michigan study. Greater human-wildlife overlap could lead to more conflict between people and animals, say the U-M researchers. But understanding where the overlap is likely to occur — […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Study suggests ‘biodegradable’ teabags don’t readily deteriorate in the environment and can adversely affect terrestrial species

Some teabags manufactured using plastic alternatives do not degrade in soil and have the potential to harm terrestrial species, a new study has shown. The research looked at commonly available teabags made using three different compositions of polylactic acid (PLA), which is derived from sources such as corn starch or sugar cane. The teabags were […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

New Zealand’s flightless birds are retreating to moa refuges

Researchers have found New Zealand’s endangered flightless birds are seeking refuge in the locations where six species of moa last lived before going extinct. An international team of researchers, led by scientists from the University of Adelaide, used fossils and computer modelling to make the discovery, shedding light on a mystery with important conservation benefits. […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Mapping the sex life of Malaria parasites at single cell resolution, reveals the genetics underlying Malaria transmission

Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the mosquito vector, the parasite has to differentiate to its sexual stage, referred to as the gametocyte stage. Unlike primary sex determination in […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Caste differentiation in ants | ScienceDaily

Most ants have two morphologically differentiated adult castes — queens and workers — each irreversibly specialized for either reproduction or nonreproductive altruism such as foraging, defense and care of maternal brood. Adult gynes (virgin queens) normally have higher body mass, wings and frontal eyes, as well as enlarged ovaries and a sperm storage organ. In […]
Written by
Automated Multiorgan CT Can Predict Diabetes, Other Conditions
  1. Pharmaceuticals and Drug Development

Automated Multiorgan CT Can Predict Diabetes, Other Conditions

Medically reviewed by Drugs.com. By Elana Gotkine HealthDay Reporter FRIDAY, Aug. 16, 2024 — Automated multiorgan computed tomography (CT), including visceral fat, can predict diabetes and associated cardiometabolic conditions, according to a study published online Aug. 6 in Radiology. Yoosoo Chang, M.D., Ph.D., from Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues […]
Written by
Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Pharmaceuticals and Drug Development

SpringWorks Therapeutics Completes Submission of New Drug Application to the FDA for Mirdametinib for the Treatment of Children and Adults with NF1-PN

Treatment for: Neurofibromatosis SpringWorks Therapeutics Completes Submission of New Drug Application to the FDA for Mirdametinib for the Treatment of Children and Adults with NF1-PN STAMFORD, Conn., July 01, 2024 (GLOBE NEWSWIRE) — SpringWorks Therapeutics, Inc. (Nasdaq: SWTX), a commercial-stage biopharmaceutical company focused on severe rare diseases and cancer, announced today that the Company has […]
Written by
Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

Post Hoc Analysis Showed CIMZIA Resulted in Meaningful Efficacy for RA Patients with High Levels of Rheumatoid Factor (RF)

ATLANTA, Nov. 11, 2023. CB, a global biopharmaceutical company, will present a post hoc analysis of the EXXELERATE trial examining the efficacy of CIMZIA (certolizumab pegol) and adalimumab in patients with rheumatoid arthritis (RA) with high rheumatoid factor (RF) levels. The data are being presented at the American College of Rheumatology (ACR) Convergence 2023 in […]
Written by
  1. Clinical

Niclosamide-based Metabolic Anticancer Drug’s First Clinical Trial Target are Prostate Cancer Patients Resistant to Hormone Therapy

SEOUL, South Korea, July 11, 2024. ADM Korea, a subsidiary of Hyundai Bioscience, announced on the 8th that the first clinical trial target population for its niclosamide-based oral metabolic anticancer drug will be ‘prostate cancer patients resistant to hormone therapy.’ Metabolic anticancer drugs regulate the metabolic pathways of cancer cells to induce their death. The […]
Written by
  1. Clinical

Approval for the First Dose Cohort in Phase 1a/b Clinical Trial of PMC-309 in Patients with Advanced or Metastatic Solid Tumors

DAEJEON, South Korea, July 8, 2024. PharmAbcine Inc., a clinical-stage biotech company focusing on next-generation antibody therapeutics, announced that PMC-309, VISTA-targeting immuno-oncology program, received safety approval for the first dose cohort (0.2mg/kg) in Phase 1a/b clinical trial for patients with advanced or metastatic solid tumors in Australia. The second dose cohort (0.5mg/kg) is currently ongoing. […]
Written by
Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas

OSAKA, Japan, October 18, 2023, and CAMBRIDGE, Massachusetts, October 17, 2023 — Takeda (TSE:4502/NYSE: TAK) today announced that the Phase 3 ADMIRE-CD II study, assessing the efficacy and safety of Alofisel® (darvadstrocel) for the treatment of complex Crohn’s Perianal Fistulas (CPF), did not meet its primary endpoint of combined remission at 24 weeks, based on […]
Written by
  1. Clinical

Turn Therapeutics Topical Atopic Dermatitis Candidate Significantly Inhibits Key Cytokines in Expansion Study of Flagship Formula

WESTLAKE VILLAGE, Calif., Aug. 5, 2024. Turn Therapeutics, a pharmaceutical and medical device company focused on immunology, advanced wound care, and dermatology, announced today positive data results of GX-03 in a biomarker study intended to measure its immunological inhibitory effects during eczema induction. The study evaluated the immunological inhibitory effects of the topical application of […]
Written by
Next
No Comments
Leave a comment Cancel
Comments to: Stealth BioTherapeutics Announces Positive Vote from FDA Advisory Committee Meeting Supporting Potential Approval of Elamipretide for the Treatment of Barth Syndrome

Login

Welcome to Life Science News!
"Explore the Latest Discoveries and Breakthroughs in Life Science with Life Science News!"
Read Smart, Save Time
Pick all the topics you are interested in to fill your homepage with stories you'll love.
Join our community
Registration is closed.